Laboratory Information

NamePMD View on WormBase
Allele designationuts
HeadPeter M. Douglas
InstitutionUT Southwestern Medical Center, Dallas, TX
Address UT Southwestern Medical Center
Molecular Biology Lab NA8.214
6000 Harry Hines Blvd.
Dallas 75235
United States
Gene classes

Strains contributed by this laboratory

Strain Genotype Species Description
PMD124 utsIs3. C. elegans utsIs3 [rab-11.2p::YFP::unc-54 3'UTR]. Transcriptional reporter for rab-11.2 activation. YFP expression is low at baseline and activated in the intestine by lipid depletion. Reference: Watterson A, et al. Nature. 2022 May;605(7911):736-740. doi: 10.1038/s41586-022-04729-7. PMID: 35585236.
PMD150 utsIs4. C. elegans utsIs4 [nhr-49p::nhr-49::GFP + myo-2p::mCherry]. Strain was back-crossed to N2 following transgene integration (parental strain described in Ratnappan R, et al. PLoS Genet. 2014 Dec 4;10(12):e1004829. doi: 10.1371/journal.pgen.1004829. ). Reference: Watterson A, et al. Nature. 2022 May;605(7911):736-740. doi: 10.1038/s41586-022-04729-7. PMID: 35585236.
PMD300 nhr-49(syb9651[sfGFP::NHR-49c]) I. C. elegans sfGFP tag inserted at the N-terminus of the endogenous NHR-49 gene (long isoform c). Derived by out-crossing parental strain PHX9542. Reference: Tatge L & Douglas PM. MicroPubl Biol. 2025 Aug 1. doi: 10.17912/micropub.biology.001655.
PMD320 nhr-49(syb10203[3xHA::TurboID::nhr-49c]) I. C. elegans 3xHA::TurboID tag with GGCG linker sequence inserted at the N-terminus of the endogenous NHR-49 gene (long isoform c). Derived by out-crossing parental strain PHX10203. Reference: Tatge L & Douglas PM. MicroPubl Biol. 2025 Aug 1. doi: 10.17912/micropub.biology.001655.
PMD342 nhr-49(syb5674[nhr-49::mCherry]) I. C. elegans mCherry tag inserted at the C-terminus of the endogenous NHR-49 locus. Derived by out-crossing parental strain PHX5674. Reference: Tatge L & Douglas PM. MicroPubl Biol. 2025 Aug 1. doi: 10.17912/micropub.biology.001655.
This laboratory hasn't submitted any alleles to the CGC.