Laboratory Information
| Name | PMD View on WormBase |
|---|---|
| Allele designation | uts |
| Head | Peter M. Douglas |
| Institution | UT Southwestern Medical Center, Dallas, TX |
| Address | UT Southwestern Medical Center Molecular Biology Lab NA8.214 6000 Harry Hines Blvd. Dallas 75235 United States |
| Gene classes |
Strains contributed by this laboratory
| Strain | Genotype | Species | Description |
|---|---|---|---|
| PMD124 | utsIs3. | C. elegans | utsIs3 [rab-11.2p::YFP::unc-54 3'UTR]. Transcriptional reporter for rab-11.2 activation. YFP expression is low at baseline and activated in the intestine by lipid depletion. Reference: Watterson A, et al. Nature. 2022 May;605(7911):736-740. doi: 10.1038/s41586-022-04729-7. PMID: 35585236. |
| PMD150 | utsIs4. | C. elegans | utsIs4 [nhr-49p::nhr-49::GFP + myo-2p::mCherry]. Strain was back-crossed to N2 following transgene integration (parental strain described in Ratnappan R, et al. PLoS Genet. 2014 Dec 4;10(12):e1004829. doi: 10.1371/journal.pgen.1004829. ). Reference: Watterson A, et al. Nature. 2022 May;605(7911):736-740. doi: 10.1038/s41586-022-04729-7. PMID: 35585236. |
| PMD300 | nhr-49(syb9651[sfGFP::NHR-49c]) I. | C. elegans | sfGFP tag inserted at the N-terminus of the endogenous NHR-49 gene (long isoform c). Derived by out-crossing parental strain PHX9542. Reference: Tatge L & Douglas PM. MicroPubl Biol. 2025 Aug 1. doi: 10.17912/micropub.biology.001655. |
| PMD320 | nhr-49(syb10203[3xHA::TurboID::nhr-49c]) I. | C. elegans | 3xHA::TurboID tag with GGCG linker sequence inserted at the N-terminus of the endogenous NHR-49 gene (long isoform c). Derived by out-crossing parental strain PHX10203. Reference: Tatge L & Douglas PM. MicroPubl Biol. 2025 Aug 1. doi: 10.17912/micropub.biology.001655. |
| PMD342 | nhr-49(syb5674[nhr-49::mCherry]) I. | C. elegans | mCherry tag inserted at the C-terminus of the endogenous NHR-49 locus. Derived by out-crossing parental strain PHX5674. Reference: Tatge L & Douglas PM. MicroPubl Biol. 2025 Aug 1. doi: 10.17912/micropub.biology.001655. |
This laboratory hasn't submitted any alleles to the CGC.