Laboratory Information

NameOW View on WormBase
Allele designationzg
HeadNollen, Ellen
InstitutionUniversity of Groningen, Groningen, The Netherlands
Address Antonius Deusinglaan 1
Internal zipcode FA50
Groningen 9713 AV
Netherlands
Website http://www.umcg.nl/EN/Research/HealthyAgeing/ERIBA/Pages/default.aspx
Gene classes afmd  hip  kmo  moag  tdo 

Strains contributed by this laboratory

Strain Genotype Species Description
OW1002 lir-3(tm813) II. C elegans Homozygous viable. Reference: Sin O, et al. Mol Cell. 2017 Mar 16;65(6):1096-1108.
OW13 grk-1(ok1239) X; pkIs2386 IV. C. elegans pkIs2386 [unc-54p::alpha-synnuclein::YFP + unc-119(+)].
OW15 grk-2(gk268) III; pkIs2386 IV. C. elegans pkIs2386 [unc-54p::alpha-synnuclein::YFP + unc-119(+)].
OW1601 dvIs62 X. C. elegans dvIs62 [snb-1p::hTDP-43/3' long UTR + mtl-2p::GFP] X. Temperature-sensitive. Maintain at 16 to minimize selection against transgene. [NOTE: Out-crossing has eliminated embryonic lethality seen in parental strain CL6049 when raised at 25C.] Uncoordinated from hatching; phenotype is stronger at higher temperatures. Intestinal GFP expression. Parental strain CL6049 out-crossed 6x to N2. Reference: Koopman M, et al. MicroPubl Biol. 2023 Apr 19:2023:10.17912/micropub.biology.000766. doi: 10.17912/micropub.biology.000766. eCollection 2023. PMID: 37151213.
OW1603 dvIs15. C. elegans dvIs15 [unc-54(vector) + mtl-2::GFP]. Control strain for OW1601. Phenotype apparently Wild-type. Parental strain CL2122 out-crossed 6x to N2. Reference: Koopman M, et al. MicroPubl Biol. 2023 Apr 19:2023:10.17912/micropub.biology.000766. doi: 10.17912/micropub.biology.000766. eCollection 2023. PMID: 37151213.
OW452 moag-4(tm4909) I. C elegans Homozygous viable. Reference: van Ham TJ, et al. Cell. 2010 Aug 20;142(4):601-12.
OW454 kynu-1(tm4924) X. C elegans C15H9.7. Homozygous viable. Reference: van der Goot AT, et al. Proc. Natl. Acad. Sci. U.S.A. 2012 109(37) 14912-7.
OW477 afmd-1(tm4547) IV. C elegans D2024.2. Homozygous viable. Reference: van der Goot AT, et al. Proc. Natl. Acad. Sci. U.S.A. 2012 109(37) 14912-7.
OW478 kmo-1(tm4529) V. C elegans R07B7.5. Homozygous viable. Reference: van der Goot AT, et al. Proc. Natl. Acad. Sci. U.S.A. 2012 109(37) 14912-7.
OW479 haao-1(tm4627) V. C elegans K06A4.5. Homozygous viable. Reference: van der Goot AT, et al. Proc. Natl. Acad. Sci. U.S.A. 2012 109(37) 14912-7.
OW715 tdo-2(zg216) III. C. elegans Crispr/Cas9 engineered deletion mutant removes 28 basepairs in tdo-2 coding region. Reference: Michels H, et al. Sci Rep. 2016 Dec 20;6:39199.
OW716 tdo-2(zg217) III. C elegans Crispr/Cas9 engineered deletion mutant removes 14 basepairs in tdo-2 coding region. Reference: Michels H, et al. Sci Rep. 2016 Dec 20;6:39199.
OW717 tdo-2(zg218) III. C elegans Crispr/Cas9 engineered deletion mutant removes 9 basepairs in tdo-2 coding region. Reference: Michels H, et al. Sci Rep. 2016 Dec 20;6:39199.
This laboratory hasn't submitted any alleles to the CGC.