Laboratory Information
| Name | OW View on WormBase |
|---|---|
| Allele designation | zg |
| Head | Nollen, Ellen |
| Institution | University of Groningen, Groningen, The Netherlands |
| Address | Antonius Deusinglaan 1 Internal zipcode FA50 Groningen 9713 AV Netherlands |
| Website | http://www.umcg.nl/EN/Research/HealthyAgeing/ERIBA/Pages/default.aspx |
| Gene classes | afmd hip kmo moag tdo |
Strains contributed by this laboratory
| Strain | Genotype | Species | Description |
|---|---|---|---|
| OW1002 | lir-3(tm813) II. | C elegans | Homozygous viable. Reference: Sin O, et al. Mol Cell. 2017 Mar 16;65(6):1096-1108. |
| OW13 | grk-1(ok1239) X; pkIs2386 IV. | C. elegans | pkIs2386 [unc-54p::alpha-synnuclein::YFP + unc-119(+)]. |
| OW15 | grk-2(gk268) III; pkIs2386 IV. | C. elegans | pkIs2386 [unc-54p::alpha-synnuclein::YFP + unc-119(+)]. |
| OW1601 | dvIs62 X. | C. elegans | dvIs62 [snb-1p::hTDP-43/3' long UTR + mtl-2p::GFP] X. Temperature-sensitive. Maintain at 16C to minimize selection against transgene. [NOTE: Out-crossing has eliminated embryonic lethality seen in parental strain CL6049 when raised at 25C.] Uncoordinated from hatching; phenotype is stronger at higher temperatures. Intestinal GFP expression. Parental strain CL6049 out-crossed 6x to N2. Reference: Koopman M, et al. MicroPubl Biol. 2023 Apr 19:2023:10.17912/micropub.biology.000766. doi: 10.17912/micropub.biology.000766. eCollection 2023. PMID: 37151213. |
| OW1603 | dvIs15. | C. elegans | dvIs15 [unc-54(vector) + mtl-2::GFP]. Control strain for OW1601. Phenotype apparently Wild-type. Parental strain CL2122 out-crossed 6x to N2. Reference: Koopman M, et al. MicroPubl Biol. 2023 Apr 19:2023:10.17912/micropub.biology.000766. doi: 10.17912/micropub.biology.000766. eCollection 2023. PMID: 37151213. |
| OW452 | moag-4(tm4909) I. | C elegans | Homozygous viable. Reference: van Ham TJ, et al. Cell. 2010 Aug 20;142(4):601-12. |
| OW454 | kynu-1(tm4924) X. | C elegans | C15H9.7. Homozygous viable. Reference: van der Goot AT, et al. Proc. Natl. Acad. Sci. U.S.A. 2012 109(37) 14912-7. |
| OW477 | afmd-1(tm4547) IV. | C elegans | D2024.2. Homozygous viable. Reference: van der Goot AT, et al. Proc. Natl. Acad. Sci. U.S.A. 2012 109(37) 14912-7. |
| OW478 | kmo-1(tm4529) V. | C elegans | R07B7.5. Homozygous viable. Reference: van der Goot AT, et al. Proc. Natl. Acad. Sci. U.S.A. 2012 109(37) 14912-7. |
| OW479 | haao-1(tm4627) V. | C elegans | K06A4.5. Homozygous viable. Reference: van der Goot AT, et al. Proc. Natl. Acad. Sci. U.S.A. 2012 109(37) 14912-7. |
| OW715 | tdo-2(zg216) III. | C. elegans | Crispr/Cas9 engineered deletion mutant removes 28 basepairs in tdo-2 coding region. Reference: Michels H, et al. Sci Rep. 2016 Dec 20;6:39199. |
| OW716 | tdo-2(zg217) III. | C elegans | Crispr/Cas9 engineered deletion mutant removes 14 basepairs in tdo-2 coding region. Reference: Michels H, et al. Sci Rep. 2016 Dec 20;6:39199. |
| OW717 | tdo-2(zg218) III. | C elegans | Crispr/Cas9 engineered deletion mutant removes 9 basepairs in tdo-2 coding region. Reference: Michels H, et al. Sci Rep. 2016 Dec 20;6:39199. |
This laboratory hasn't submitted any alleles to the CGC.