Laboratory Information
Name | OQ View on WormBase |
---|---|
Allele designation | ulb |
Head | Patrick Laurent |
Institution | ULB Neuroscience Institute (UNI), Brussels, Belgium |
Address | ULB, campus ERASME building C-C3-143 808 route de lennik brussels 1070 Belgium |
Gene classes |
Strains contributed by this laboratory
Strain | Genotype | Species | Description |
---|---|---|---|
OQ192 | gmap-1(ulb13) X. | C. elegans | CRISPR/Cas9 engineered 1515 bp deletion of gmap-1; flanking sequences ACCTATCCAAAGCTT and TGCCAAGACATTGAA. Dessication sensitive. Shorter body length. Increased permeability of the cuticle. Reference: Ngale Njume F, et al. iScience. 2022 Oct 14;25(11):105357. doi: 10.1016/j.isci.2022.105357. PMID: 36339267. |
OQ195 | gmap-1(ulb13) X; ulbEx112. | C. elegans | ulbEx112 [gmap-1p::gmap-1(cDNA)::SL2::GFP + unc-122p::RFP]. Pick animals with RFP+ expression in coelomocytes to maintain. ulb13 is a CRISPR/Cas9 engineered 1515 bp deletion of gmap-1; flanking sequences ACCTATCCAAAGCTT and TGCCAAGACATTGAA. Expression of exogenous gmap-1 quantifiable via the GFP signal. Reference: Ngale Njume F, et al. iScience. 2022 Oct 14;25(11):105357. doi: 10.1016/j.isci.2022.105357. PMID: 36339267. |
OQ366 | tsp-6(syb4122[tsp-6::wrmScarlet]) X; ulbEx78 [F16F9.3p::CFP]. | C. elegans | ulbEx78 [F16F9.3p::CFP]. Pick CFP+ to maintain. wrmScarlet expression in ciliated neurons provides a useful marker to track ciliary production of extracellular vesicles and their subsequent engulfment by the surrounding glial cells (AMsh, PHsh). Reference: Razzauti A & Laurent P. Elife. 2021 Sep 17:10:e67670. doi: 10.7554/eLife.67670. PMID: 34533135. |
PHX4122 | tsp-6(syb4122[tsp-6::wrmScarlet]) X. | C. elegans | wrmScarlet tag inserted at C-terminus of endogenous tsp-6 locus. wrmScarlet expression in ciliated neurons provides a useful marker to track ciliary production of extracellular vesicles. Reference: Razzauti A & Laurent P. Elife. 2021 Sep 17:10:e67670. doi: 10.7554/eLife.67670. PMID: 34533135. |
PHX5270 | ctns-1(syb5270[ctns-1::wrmScarlet]) II. | C. elegans | wrmScarlet tag inserted at C-terminus of endogenous stns-1 locus. Lysosomal marker. Reference: Ngale Njume F, et al. iScience. 2022 Oct 14;25(11):105357. doi: 10.1016/j.isci.2022.105357. PMID: 36339267. |
This laboratory hasn't submitted any alleles to the CGC.