Laboratory Information

NameOCF View on WormBase
Allele designationocf
HeadOrna Cohen-Fix
InstitutionNIH, NIDDK, Bethesda, MD
Address NIH, NIDDK, LCMB
Building 8 Room 319
8 Center Dr
Bethesda 20892
United States
Website http://intramural.niddk.nih.gov/research/faculty.asp?People_ID=1564
Gene classes lpin 

Strains contributed by this laboratory

Strain Genotype Species Description
AG175 unc-119(ed3) III; avEx122. C. elegans avEx122 [(pAG126) lpin-1p::GFP::lpin-1::lpin-1 3'UTR + unc-119(+)]. No GFP expression detected in germline.
AG176 unc-119(ed3) III; avEx123. C. elegans avEx123 [lpin-1p::GFP::his-58::lpin-1 3'UTR + unc-119(+)]. No GFP expression detected in germline.
OCF12 lpin-1(ok2761) V/nT1 [qIs51] (IV;V). C. elegans Heterzygotes are wildtype and GFP+. lpin-1(ok2761) homozygotes die as L1 larvae. Homozygous nT1[qIs51] inviable.
OCF13 lpin-1(ok2761)/sqt-3(sc8) unc-61(e228) V; ltIs37 IV; jjIs1092. C. elegans jjIs1092 [(pNUT1) npp-1::GFP + unc-119(+)]. ltIs37 [(pAA64) pie-1p::mCherry::his-58 + unc-119(+)] IV. Heterozygotes are wildtype with GFP+ and mCherry+. lpin-1(ok2761) homozygotes die as L1 larvae. Also segregates Unc Rol.
OCF15 unc-119(ed3); ocfIs2. C. elegans ocfIs2 [pie-1p:mCherry::sp12::pie-1 3'UTR + unc-119(+)]. Stable germline and embryonic expression of ER and NE marker, useful for following NE dynamics through early development. Reference: Joseph-Strauss D, et al. Dev Biol. 2012 May 15;365(2):445-57.
OCF22 unc-119(ed3) III; ocfIs5. C. elegans ocfIs5 [pie-1p::mCherry::npp-1::pie-1 3'UTR + unc119(+)]. Reference: Joseph-Strauss D, et al. Dev Biol. 2012 May 15;365(2):445-57.
OCF3 unc-119(ed3) III; ltIs37 IV; jjIs1092. C. elegans jjIs1092 [(pNUT1) npp-1::GFP + unc-119(+)]. ltIs37 [(pAA64) pie-1p::mCherry::his-58 + unc-119(+)] IV. Non-Unc.
OCF4 unc-119(ed3) III; ltIs37 IV; qaIs3502. C. elegans qaIs3502 [YFP::lmn-1 + CFP::H2B + unc-119(+)]. ltIs37 [(pAA64) pie-1p::mCherry::his-58 + unc-119(+)] IV. Non-Unc.
OCF69 ocfSi1 I; unc-119(ed3) III. C. elegans ocfSi1 [mex-5p::Dendra2::his-58/66::tbb-2 3'UTR + unc-119(+)] I. Dendra2::histone H2B expression in the germline and embryos. The H2B coding sequence is identical to genes his-58 and his-66. Made by MosSCI insertion into ttTi4348 on LG I. Reference: Rosu S & Cohen-Fix O. Dev Biol. 2017 Mar 15;423(2):93-100.
This laboratory hasn't submitted any alleles to the CGC.