Caenorhabditis Genetics Center (CGC)

Laboratory Information

NameNJ View on WormBase
Allele designationrh
HeadHedgecock, Ed
InstitutionJohns Hopkins University, Baltimore, MD
Address Department of Biology Johns Hopkins University 3400 North Charles Street Baltimore, MD 21218-2685

Website http://hedgecock.bio.jhu.edu
Gene classes adn  can  cul  epi  exc  inb  lam  lat  lmb  mth  mua  mup  pvp 

Strains contributed by this laboratory

Strain Genotype Species Description
CB3241 clr-1(e1745) II. C. elegans Temperature sensitive lethal: inviable at 25C, grows at 20C and 15C. Somewhat sickly. Small brood sizes. At 25C homozygotes have a starved translucent appearance, facilitating Nomarski visualization of neuron processes.
CB3256 mab-5(e1751) III. C. elegans Semidominant Unc(mild). Intragenic revertants common.
CB3303 mig-1(e1787) I. C. elegans QL migration reversed, HSN migration defective. Egl.
CB3323 che-13(e1805) I. C. elegans No FITC uptake by phasmids and amphids. Dauer formation defective. Osmotic avoidance defective.
CB3329 che-10(e1809) II. C. elegans Defective osmotic avoidance. FITC-.
CB3330 che-11(e1810) V. C. elegans Defective in osmotic avoidance. FITC-. Dauer defective.
CB3332 che-12(e1812) V. C. elegans Defective osmotic avoidance. FITC uptake abnormal.
CB3383 cat-6(e1861) V. C. elegans Sensory neurons CEP, ADE, PDE take up FITC; tubular body of CEP cilia disrupted; slightly defective dauer formation.
CB3388 ncl-1(e1865) III. C. elegans Abnormal large nucleoli in all cells.
CB3687 che-14(e1960) I. C. elegans Some FITC uptake by amphids but not by phasmids. Hypodermal defect.
NJ185 daf-9(rh50) X. C. elegans Unreflexed gonad. Previously known as mig-8.
NJ207 daf-12(rh62) X C. elegans Daf-constitutive allele rh62 forms partial-dauer larvae under replete conditions at all temperatures.
NJ211 can-1(rh67) III. C. elegans Shortened excretory canal.
NJ227 daf-12(rh84) X C. elegans Delayed gonadal and extragonadal development. Hermaphrodites (n=100), 74%
NJ228 mua-6(rh85) X. C. elegans Poorly growing strain; most homozygotes fail to reach adulthood, and those that do are Egl. smg suppressable and tends to accumulate second site mutations that suppress the Mua phenotype and restore vigorous growth.
NJ242 exc-2(rh90) X. C. elegans Formation of large round cysts in the excretory canal. The cysts begin to form shortly before hatching and is penetrant. The cysts grow in size throughout larval and adult stages, and can be lethal. The cysts form primarily at the cell body. Some of the larger cysts may be visible by low power microscopy. Slight variable defects in the tail whip. 100% penetrant.
NJ261 dpy-24(rh97) I. C. elegans DTC reflexes but goes wrong way dorsal.
NJ268 pat-3(rh96) III. C. elegans Short excretory canal, incomplete QR, HSN migrations, post DTC loops.
NJ298 mig-15(rh80) X. C. elegans Abnormal body shape. Unc. Severity of phenotype: rh326 > rh80 > rh148.
NJ340 exc-2(rh105) X. C. elegans Short swollen, bubbly excretory canal (resembles rh90).
NJ341 unc-14(rh106) I. C. elegans Reduced PVP staining, Unc.
NJ363 unc-128(rh110) X. C. elegans Extra Mab44 reactive neurons in head.
NJ365 unc-14(rh111) I. C. elegans PVP varicosities, amphid -, phasmid - , CEP+.
NJ469 exc-4(rh133) I. C. elegans Formation of large round cysts in the excretory canal. The cysts begin to form shortly before hatching and is penetrant. The cysts grow in size throughout larval and adult stages, and can be lethal. The cysts form primarily at the cell body. Some of the larger cysts may be visible by low power microscopy. Slight variable defects in the tail whip.
NJ479 unc-104(rh43) II. C. elegans Unc.
NJ490 mig-15(rh148) X. C. elegans Abnormal body shape. Unc. Severity of phenotype: rh326 > rh80 > rh148.
NJ523 cul-1(rh173) dpy-18(e499) III. C. elegans cul-1 was formerly known as lin-19.
NJ524 mua-2(rh174) dpy-18(e499) III. C. elegans Mua, late L4, tail first. Ventral cord abnormal.
NJ545 mua-4(rh177) dpy-17(e164) III. C. elegans Mua, not viable. Cytokinesis is defective in both hypodermis and germline resulting in mutinucleate cells.
NJ546 unc-116(rh24) III; cat-6(e1861) V. C. elegans Paralyzed Unc. Abnormal excretory canal. Abnormal amphid sheath cell.
NJ549 dpy-10(e128) unc-104(rh142)/mnC1 [dpy-10(e128) unc-52(e444)] II. C. elegans Severe unc-104 allele, hypercontracted coiler. Dpy heterozygotes segregate Dpy, mnC1 dpy-10 unc-52 homozygotes (paralyzed Dpy), and very small and sick dpy-10 unc-104 homozygotes.
NJ600 exc-8(rh210) X. C. elegans Variable length excretory canal. Moderate, regional enlargement with occasional septations. Channel branches.
NJ682 exc-3(rh251) X. C. elegans Cystic canal.
NJ701 klf-3(rh160) II. C. elegans Poorly growing strain; most homozygotes fail to reach adulthood, and those that do are Egl. klf-3 was formerly known as mua-1.
NJ702 mua-2(rh119) III. C. elegans
NJ731 exc-5(rh232) IV. C. elegans Formation of large round cysts in the excretory canal. The cysts begin to form shortly before hatching and is penetrant. The cysts grow in size throughout larval and adult stages, and can be lethal. The cysts form primarily at the canal tips. Some of the larger cysts may be visible by low power microscopy. Slight variable defects in the tail whip. Impenetrant distal tip cell migration defects (Mig).
NJ824 rhIs15. C. elegans rhIs15 [mig-15::GFP]. Superficially. GFP is brighter at 25C.
NJ834 mig-15(rh326) X. C. elegans Abnormal body shape. Unc. Severity of phenotype: rh326 > rh80 > rh148.

Alleles contributed by this laboratory

Allele Type DNA Change Protein Change
rh257 Allele substitution splice_site
rh286 Allele substitution
rh61 Allele substitution nonsense
rh412 Allele
rh84 Allele substitution nonsense
rh284 Allele substitution
rh62 Allele substitution
rh157 Allele deletion
rh285 Allele substitution nonsense
rh411 Allele
rh273 Allele substitution
rh193 Allele substitution
rh274 Allele substitution
rh319 Allele substitution nonsense
rh50 Allele substitution
rh148 Allele substitution
rh80 Allele substitution nonsense
rh40 Allele substitution
rh85 Allele substitution
rh90 Allele
rh116 Allele
rh133 Allele
rh43 Allele substitution
rh26 Allele
rh24 Allele
rh142 Allele substitution nonsense
rh207 Allele
rh252 Allele deletion
rh160 Allele insertion
rh119 Allele
rh232 Allele deletion
rh186 Allele
rh103 Allele substitution
rh326 Allele substitution nonsense
rh1024 Allele
rh197 Allele
rh195 Allele
rh267 Allele
rh94 Allele substitution splice_site
rh147 Allele substitution nonsense
rh308 Allele substitution nonsense
rh300 Allele substitution
rh315 Allele substitution nonsense