Laboratory Information
| Name | MS View on WormBase |
|---|---|
| Allele designation | ir |
| Head | Morris Ford Maduro |
| Institution | University of California, Riverside, CA |
| Address | University of California,Riverside Biology Dept. Rm 1229 Spieth Hall-Gina Maduro 3401 Watkins Dr Riverside 92521 United States |
| Website | http://www.faculty.ucr.edu/~mmaduro/ |
| Gene classes | dlx msi vde |
Strains contributed by this laboratory
| Strain | Genotype | Species | Description |
|---|---|---|---|
| JR1904 | wIs117. | C. elegans | wIs117 [med-1p::GFP::pop-1::med-1 3'UTR + rol-6(su1006)]. Rollers. Reference: Maduro MF, Lin R & Rothman JH. 2002. Developmental Biology 248: 128-142. |
| JR2274 | wIs137 V. | C. elegans | wIs137 [end-3p::end-3(P202L)::GFP + rol-6(su1006)] V. Rollers. Reference: Maduro MF, et al. Dev Biol. 2005 Aug 15;284(2):509-22. |
| MS1180 | irIs83. | C. elegans | irIs83 contains [pMM824 (unc-119::mCherry) + pMM768 (end-3(+))]. isIs83 formed by spotaneous integration of an Ex array in an end-1,3(-) mutant background and was backcrossed to remove end-1,3(-). irIs83 is likely not integrated on LG III, V, or X. |
| MS1206 | ceh-51(tm2123) V; irEx540. | C. elegans | irEx540 [ceh-51(+) + unc-119::CFP + rol-6(su1006)]. Throws arrested ceh-51(-) larvae, rescued animals expressing unc-119::CFP, and some unc-119::CFP-expressing larvae that are not rescued. Heterozygous mutant strain originally obtained from Shohei Mitani. |
| MS123 | med-2(cx9744) III. | C. elegans | Mos1 insertion into coding region of K04C2.6 (med-2). No obvious phenotype. |
| MS1893 | unc-119(ed9) III; irSi24 IV. | C. elegans | irSi24 [pept-1::mCherry::H2B + Cbr-unc-119(+)] IV. Single-copy MosSCI insertion of pept-1 reporter into cxTi10882 site in LG IV. mCherry fluorescence exclusively in intestinal nuclei from the end of embryonic development through adulthood. Generated in N2 background. Reference: Maduro MF, et al. Dev Biol 2015 Aug 1;404(1):66-79. doi: 10.1016/j.ydbio.2015.04.025, PMID:25959238. |
| MS231 | dpy-17(e164) ncl-1(e1865) unc-36(e251) III; irDp1 (III;f). | C. elegans | Superficially WT. Pick WT to propagate. Throws WT (expressing unc-119::YFP) and DpyUncs. irDp1 is sDp3 carrying a spontaneous integrant of an array carrying unc-119::YFP + unc-32(+) + med-1(+), originally generated in BC4638. irDp1 appears to complement everything sDp3 does and has a similar meiotic transmission frequency of 60%. In another strain, irDp2 was observed to lose ability to complement dpy-17. irDp1 confers a progressive adult egg laying defect (also seen with sDp3). |
| MS438 | irIs25 V. | C. elegans | irIs25 [elt-2::NLS::GFP::lacZ + rol-6(su1006)] V. |
| MS662 | tbx-35(tm1789) II; irEx274. | C. elegans | irEx274 [ZK177 + unc-119::CFP + rol-6(su1006)]. Maintain by picking Rollers. Strain throws Rollers (expressing unc-119::CFP), dead eggs, and developmentally-arrrested L1s. Roller is often weak or not apparent. A greater proportion of tbx-35(tm1789) embryos will hatch as inviable L1s at 15C as compared with 20C or 25C. |
This laboratory hasn't submitted any alleles to the CGC.