Laboratory Information

NameMS View on WormBase
Allele designationir
HeadMorris Ford Maduro
InstitutionUniversity of California, Riverside, CA
Address University of California,Riverside
Biology Dept. Rm 1229 Spieth Hall-Gina Maduro
3401 Watkins Dr
Riverside 92521
United States
Gene classes dlx  msi  vde 

Strains contributed by this laboratory

Strain Genotype Species Description
JR1904 wIs117. C. elegans wIs117 [med-1p::GFP::pop-1::med-1 3'UTR + rol-6(su1006)]. Rollers. Reference: Maduro MF, Lin R & Rothman JH. 2002. Developmental Biology 248: 128-142.
JR2274 wIs137 V. C. elegans wIs137 [end-3p::end-3(P202L)::GFP + rol-6(su1006)] V. Rollers. Reference: Maduro MF, et al. Dev Biol. 2005 Aug 15;284(2):509-22.
MS1180 irIs83. C. elegans irIs83 contains [pMM824 (unc-119::mCherry) + pMM768 (end-3(+))]. isIs83 formed by spotaneous integration of an Ex array in an end-1,3(-) mutant background and was backcrossed to remove end-1,3(-). irIs83 is likely not integrated on LG III, V, or X.
MS1206 ceh-51(tm2123) V; irEx540. C. elegans irEx540 [ceh-51(+) + unc-119::CFP + rol-6(su1006)]. Throws arrested ceh-51(-) larvae, rescued animals expressing unc-119::CFP, and some unc-119::CFP-expressing larvae that are not rescued. Heterozygous mutant strain originally obtained from Shohei Mitani.
MS123 med-2(cx9744) III. C. elegans Mos1 insertion into coding region of K04C2.6 (med-2). No obvious phenotype.
MS1893 unc-119(ed9) III; irSi24 IV. C. elegans irSi24 [pept-1::mCherry::H2B + Cbr-unc-119(+)] IV. Single-copy MosSCI insertion of pept-1 reporter into cxTi10882 site in LG IV. mCherry fluorescence exclusively in intestinal nuclei from the end of embryonic development through adulthood. Generated in N2 background. Reference: Maduro MF, et al. Dev Biol 2015 Aug 1;404(1):66-79. doi: 10.1016/j.ydbio.2015.04.025, PMID:25959238.
MS231 dpy-17(e164) ncl-1(e1865) unc-36(e251) III; irDp1 (III;f). C. elegans Superficially WT. Pick WT to propagate. Throws WT (expressing unc-119::YFP) and DpyUncs. irDp1 is sDp3 carrying a spontaneous integrant of an array carrying unc-119::YFP + unc-32(+) + med-1(+), originally generated in BC4638. irDp1 appears to complement everything sDp3 does and has a similar meiotic transmission frequency of 60%. In another strain, irDp2 was observed to lose ability to complement dpy-17. irDp1 confers a progressive adult egg laying defect (also seen with sDp3).
MS438 irIs25 V. C. elegans irIs25 [elt-2::NLS::GFP::lacZ + rol-6(su1006)] V.
MS662 tbx-35(tm1789) II; irEx274. C. elegans irEx274 [ZK177 + unc-119::CFP + rol-6(su1006)]. Maintain by picking Rollers. Strain throws Rollers (expressing unc-119::CFP), dead eggs, and developmentally-arrrested L1s. Roller is often weak or not apparent. A greater proportion of tbx-35(tm1789) embryos will hatch as inviable L1s at 15C as compared with 20C or 25C.
This laboratory hasn't submitted any alleles to the CGC.