Laboratory Information
| Name | LW View on WormBase |
|---|---|
| Allele designation | jj |
| Head | Jun (Kelly) Liu |
| Institution | Cornell University, Ithaca NY, USA |
| Address | 441 Biotechnology Building Cornell University Ithaca 14853 United States |
| Website | http://courses.cit.cornell.edu/liulab/ |
| Gene classes | drag rcor snu susm |
Strains contributed by this laboratory
| Strain | Genotype | Species | Description |
|---|---|---|---|
| LW1089 | unc-119(ed4) III; jjIs1089. | C. elegans | jjIs1089 [npp-1::GFP + unc-119(+)]. Reference: J Cell Sci. 2009 Jun 15;122(Pt 12):1970-8. |
| LW1288 | arIs37 I; sma-6(jj1) II; cup-5(ar465) III. | C. elegans | arIs37 [myo-3p::ssGFP + dpy-20(+)] I. Small body size and 6 coelomocytes. myo-3p::ssGFP is a secreted GFP that is taken up by coelomocytes. |
| LW227 | mls-2(cc615) X. | C. elegans | Defects in postembryonic M lineage: randomized cleavage orientations, reduced cell proliferation, cell fate transformation from CCs and BWMs to SMs. About 30% larval and adult lethality. |
| LW2286 | lon-2(e678) X; jjIs2277. | C. elegans | jjIs2277 [pCXT51(5*RLR::pes-10p(deleted)::GFP) + LiuFD61(mec-7p::RFP)]; integrated on LG I or IV. Reference: Tian et al. (2010) Development 137(14):2375-84. |
| LW2308 | dbl-1(wk70) V; jjIs2277. | C. elegans | jjIs2277 [pCXT51(5*RLR::pes-10p(deleted)::GFP) + LiuFD61(mec-7p::RFP)]; integrated on LG I or IV. Reference: Tian et al. (2010) Development 137(14):2375-84. |
| LW2367 | arIs37 I; sma-9(cc604) X. | C. elegans | arIs37 [myo-3p::ssGFP + dpy-20(+)] I. myo-3p::ssGFP is a secreted GFP that is taken up by coelomocytes. Reference: Tian et al. (2010) Development 137(14):2375-84. |
| LW2436 | jjIs2277. | C. elegans | jjIs2277 [pCXT51(5*RLR::pes-10p(deleted)::GFP) + LiuFD61(mec-7p::RFP)]; integrated on LG I or IV. Reference: Tian et al. (2010) Development 137(14):2375-84. |
| LW257 | fozi-1(cc609) cup-5(ar465) III; him-5(e1467) V. | C. elegans | Missing M-derived coelomocytes and 1-3 body wall muscles. Cells transformed to sex myoblast-like fates. |
| LW425 | mls-2(tm252) X. | C. elegans | Defects in postembryonic M lineage: over-proliferation, cell fate transformation. |
| LW478 | sma-9(tm572) X. | C. elegans | |
| LW5558 | sma-4(jj278) III. | C. elegans | sma-4(jj278) worms are small, and the mutation can suppress the sma-9(0) loss of M-derived coelomocyte defect. sma-4(jj278) is a true molecular null allele of sma-4; the 3,556 bp deletion (position: Chromosome III: 5,816,203….5,819,759) removes almost the entire coding region of sma-4. Reference: McKillop AN, et al. (2018). A new deletion allele of sma-4. microPublication Biology. https://doi.org/10.17912/Z4Z9-CE10. |
| LW557 | arIs37 I; fozi-1(cc607) cup-5(ar465) III. | C. elegans | arIs37 [myo-3p::ssGFP + dpy-20(+)] I. Missing M-derived coelomocytes and 1-3 body wall muscles. Cells transformed to sex myoblast-like fates. myo-3p::ssGFP is a secreted GFP that it taken up by coelomocytes. |
| LW614 | arIs37 I; sma-3(jj3) cup-5(ar465) III. | C. elegans | arIs37 [myo-3p::ssGFP + dpy-20(+)] I. Small body size and 6 coelomocytes. myo-3p::ssGFP is a secreted GFP that is taken up by coelomocytes. |
| LW697 | ccIs4810 X. | C. elegans | ccIs4810 [(pJKL380.4) lmn-1p::lmn-1::GFP::lmn-1 3'utr + (pMH86) dpy-20(+)] I. GFP-tagged LMN-1 is expressed in all somatic cells. Reference: Haithcock E, et al. (2005) PNAS 102:16690-5. |
| LW699 | jjIs699. | C. elegans | jjIs699 [lmn-1p::emr-1::GFP::unc-54 3'UTR + unc-119(+)]. Reference: Haithcock E., et al. PNAS. 2005 Nov 15;102(46):16690-5. |
| LW709 | jjIs709 I. | C. elegans | jjIs709 [(pDRNL1) + lmn-1p::GFP::lmn-1::unc-54 3'utr + (pMH86) dpy-20(+)] I. GFP-tagged LMN-1 is expressed in all somatic cells. Reference: Haithcock E, et al. (2005) PNAS 102:16690-5. |
| LW905 | lmn-1(tm1502) I/hT2 [bli-4(e937) let-?(q782) qIs48] (I;III). | C. elegans | Heterozygotes are WT with pharyngeal GFP signal, and segregate WT GFP, arrested hT2 aneuploids, and non-GFP tm1502 homozygotes (sterile). Homozygous hT2[bli-4 let-? qIs48] inviable. Pick WT GFP and check for correct segregation of progeny to maintain. |
Alleles contributed by this laboratory
| Allele | Type | DNA Change | Protein Change |
|---|---|---|---|
| jj1 | Allele | substitution | nonsense |
| jj3 | Allele | substitution | splice_site |