Laboratory Information

NameLA View on WormBase
Allele designationpf
HeadLakowski, Bernard
InstitutionManhattanville College, Purchase, NY
Address Nematode Genetics Laboratory Department of Neuroscience Pasteur Institute 25 rue du Docteur Roux Paris, 75724

Gene classes pptr 

Strains contributed by this laboratory

Strain Genotype Species Description
LA59 spr-3(by108) X. C. elegans Superficially WT. by108 completely suppresses the Egl defect of sel-12 mutants. by108 derepresses the transcription of hop-1 in the early larval stages. This strain may not be used for commercial purposes.
LA62 byDf1 X. C. elegans Superficially WT. byDf1 completely suppresses the Egl defect of sel-12 mutants. byDf1 derepresses the transcription of hop-1 in the early larval stages. byDf1 is a deletion of 31,069 bases from position 3052 of cosmid F46H6 to position 6698 of cosmid C07A12 with a single A base pair insertion. byDf1 deletes F46H6.2/dgk-2, F46H6.4, F46H6.1/rhi-1, C07A12.5/spr-3 and part of C07A12.7. byDf1 is null for spr-3 by sequence and northern analysis. Deletion can be detected with the primers RB1222 CTT ACT AGT ACT AGC TCG CG and RB1224 CCT GTC CAT AAG TGC AGT CC, which give a product of 1540 bp. This strain may not be used for commercial purposes.
LA95 spr-4(by105) I. C. elegans Superficially WT. by1-5 strongly suppresses the Egl defect of sel-12 mutants. About 5% of spr-4(by105) I; sel-12(ar171) X double mutants are Egl. This strain may not be used for commercial purposes.

Alleles contributed by this laboratory

Allele Type DNA Change Protein Change
pf2 Allele deletion
pf159 Allele deletion
pf88 Allele deletion