Caenorhabditis Genetics Center (CGC)

Laboratory Information

NameKN View on WormBase
Allele designationhu
HeadRik Korswagen
InstitutionHubrecht Institute
Address Uppsalalaan 8
Utrecht 3584 CT
Netherlands
Website http://www.hubrecht.eu/research/korswagen/index.html
Gene classes axl  pdd  sfrp 

Strains contributed by this laboratory

Strain Genotype Species Description
KN1510 huIs120. C. elegans huIs120 [hsp-16.2p::sfrp-1 + myo-2p::Tomato]. Wild-type under normal culture conditions. Heat-shock (10 min) during embryogenesis causes embryonic lethality and HSN migration defects. Heat-shock (10 min) at hatching causes Ql and QR migration defects. Reference: Harterink M, et al. Development. 2011 Jul;138(14):2915-24.
KN259 huIs33. C. elegans huIs33 [sod-3::GFP + rol-6(su1006)]. Pick Rollers to maintain.
KN369 muIs32 II; egl-20(hu105) IV. C. elegans muIs32 [mec-7p::GFP + lin-15(+)]. Egl. Anterior migration of the QL.d, defects in QR.d and HSN migration.
KN387 muIs32 II; egl-20(hu120) IV. C. elegans muIs32 [mec-7p::GFP + lin-15(+)]. Egl. Anterior migration of the QL.d, defects in QR.d and HSN migration.
KN4 huIs4. C. elegans huIs4 [hsp-16.2p::pop-1(delta N) + rol-6(su1006)]. Rollers. Truncated pop-1 fragment encoding delta N-POP-1(45-438) driven by heat-shock promotor hsp-16.2. Reference: Korswagen et al. (2000) Nature 406: 527-32.
KN478 daf-16(mu86) I; huIs33. C. elegans huIs33 [sod-3::GFP + rol-6(su1006)]. Pick Rollers to maintain.
KN53 huIs7. C. elegans huIs7 [hsp-16.2p::Myc::bar-1(delta N) + mec-7p::GFP + dpy-20(+)]. Muv. Posterior migration of the QR descendants. Reference: de Groot et al. (2014) Science Signal. Ra26.
KN555 vps-35(hu68) II. C. elegans QL.d localize in anterior. HSN neurons fail to migrate. Strong egg-laying defect.
KN562 pop-1(hu9) I; muIs32 II. C. elegans muIs32 [mec-7p::GFP + lin-15(+)]. QL daughter cells (e.g. PVM) migrate to positions anterior of the vulva in about 25% of the animals.
KN611 axl-1(tm1095) I. C. elegans tm1095 enhances Q neuroblast migration and vulva induction phenotype of pry-1. Minor defect in excretory cell development. Reference: Oosterveen et al. (2007) Dev Biol 308: 438-48.
KN637 axl-1(tm1095) I; muIs32 II; bar-1(ga80) X. C. elegans muIs32 [mec-7p::GFP + lin-15(+)] II. Reference: Oosterveen et al. (2007) Dev Biol 308: 438-48.
KN644 pop-1(hu9) axl-1(tm1095) I; muIs32 II. C. elegans muIs32 [mec-7p::GFP + lin-15(+)] II. Reference: Oosterveen et al. (2007) Dev Biol 308: 438-48.
KN689 axl-1(tm1095) pry-1(mu38) I; muIs32 II; huEx83. C. elegans muIs32 [mec-7p::GFP + lin-15(+)] II. huEx83 [pry-1p::axl-1::GFP + myo-2p::GFP]. Pick animals with GFP+ pharynx to maintain. Reference: Oosterveen et al. (2007) Dev Biol 308: 438-48.
KN720 dpy-20(e1282) IV; huIs60. C. elegans huIs60 [egl-20p::egl-20::protA + dpy-20(+)].
KN800 lon-8(hu187) V. C. elegans Long body size.
KN846 lon-8(hu188) V. C. elegans Long body size.

Alleles contributed by this laboratory

Allele Type DNA Change Protein Change
hu105 Allele
hu120 Allele
hu68 Allele deletion
hu9 Allele
hu187 Allele deletion
hu188 Allele deletion