Laboratory Information

NameJY View on WormBase
Allele designationyz
HeadSze, Ji Ying
InstitutionAlbert Einstein College of Medicine, Bronx, NY
Address Dept of Molecular Pharmacology Albert Einstein College of Medicine 202 Golding building 1300 Morris Park Ave. Bronx, NY 10461

Gene classes nss 

Strains contributed by this laboratory

Strain Genotype Species Description
GR1321 tph-1(mg280) cam-1(vs166) II. C. elegans Slow pumping. Egg laying defective. Low frequency of dauer formation. Residual serotonin immunoreactivity, rare and very faint (<1% of NSMs) in most stages, but nearly 100% of CP neurons in adult males show faint to moderate serotonin immunoreactivity. Males mate quite well (E. Hare and C. Loer). Some phenotypic defects originally attributed to mg280 in this strain are likely due to vs166. vs166 is a large deletion (approx. 9.8kb) in the cam-1 gene; flanking sequences are: 5'-gctactggtaaataaggtaa-3' and 5'-atgcttttaaagtttatatt-3' (Edith Myers, personal commnication). See MT15434 for a strain carrying mg280 without the cam-1 mutation.
JY190 osm-9(yz6) IV. C. elegans Downregulation of tph-1::GFP expression in the ADF neurons. CORRECTION: The yz6 allele had been erroneously listed as y26 in our database.
JY243 ocr-2(yz5) IV. C. elegans Downregulation of tph-1::GFP expression in the ADF neurons.
JY359 lim-4(yz12) X. C. elegans Down regulation of tph-1::GFP expression in the ADF neurons.

Alleles contributed by this laboratory

Allele Type DNA Change Protein Change
yz6 Allele substitution nonsense
yz5 Allele substitution
yz12 Allele deletion