Laboratory Information

NameJR View on WormBase
Allele designationw
HeadJoel H. Rothman
InstitutionUniversity of California, Santa Barbara CA, USA
Address Rothman Lab / NRI
Biology 2, Bldg. 571, rm 6131
UCSB
Santa Barbara 93106-5060
United States
Website http://www.lifesci.ucsb.edu/mcdb/labs/rothman/labpage.htm
Gene classes cep  dad  die  dpr  end  fus  hnl  icd  med  odd  pel  plp  zen 

Strains contributed by this laboratory

Strain Genotype Species Description
CB4817 wDf5(e500)/mnC1 [dpy-10(e128) unc-52(e444)] II. C. elegans Heterozygotes are WT and segregate WT, DpyUncs and dead eggs.
JR113 sma-1(e30) unc-76(e911) wDf2/sqt-3(sc8) unc-61(e228) V. C. elegans Heterozygotes are WT and segregate WT, RolUncs and dead eggs. Homozygous wDf1 embryos arrest uniformly as unenclosed balls of differentiated cells. wDf2 formerly called zen-1(w1). sc8 previously called rol-4(sc8).
JR1279 cep-1(+) I; cep-1(w40). C. elegans Resistant to germ cell death induced by ionizing radiation. Sensitive to hypoxia and starvation stresses. This strain contains an intact copy of the gene at the normal locus on LG I. w40 is a translocated partially deleted copy of the cep-1 locus that has a dominant-negative effect on cep-1 function and is not linked to the chromosomal location of cep-1.
JR1380 die-1(w34)/mnC1 [dpy-10(e128) unc-52(e444)] II. C. elegans Heterozygotes are wild type and segregate wild type, paralyzed Dpys, and die-1 homozygous embryos.
JR1763 wcDf1 dpy-1(e1)/daf-7(e1372) par-2(it46) III. C. elegans At 25C, heterozygotes are WT and segregate WT, dead eggs and Dauers (which will give only dead eggs if they exit dauer). e1372 and it46 are both temperature sensitive.
JR2370 egl-18(ok290) IV. C. elegans
JR2750 bli-6(sc16) unc-22(e66)/unc-24(e138) vha-17(w13) dpy-20(e2017) IV. C. elegans Pick wild type animals to maintain.
JR41 unc-76(e911) wDf1/unc-61(e228) dpy-21(e428) V. C. elegans Heterozygotes are WT and segregate WT, DpyUncs and dead eggs. Homozygous wDf1 embryos arrest uniformly as unenclosed balls of differentiated cells. wDf1 formerly called zen-1(e2482). 2/02: dpy-21 appears to have been lost from this strain.
JR417 wDf3/dpy-? V. C. elegans Pick WT to maintain. This strain is balanced by a dumpy, but not sure which one. wDf3 arrests as dead eggs with no gut.
JR423 rhDf1/qC1 [dpy-19(e1259) glp-1(q339)] III. C. elegans Heterozygotes are WT and segregate WT, Dpy Steriles and dead eggs.
JR667 unc-119(e2498::Tc1) III; wIs51 V. C. elegans wIs51 [SCMp::GFP + unc-119(+)] V. GFP expression in seam cells. Superficially wild-type.
JR728 sqt-3(sc8) unc-61(e228)/wDf4 V. C. elegans Pick WT to maintain. Throws WT, Roller Uncs and dead eggs. wDf4 arrests as dead eggs with no gut. sc8 previously called rol-4(sc8).
JR8 die-1(e2500)/mnC1 [dpy-10(e128) unc-52(e444)] II; him-8(e1489) IV. C. elegans Heterozygotes are WT and segregate WT, paralyzed Dpys, and arrested embryos. Throws males. e2500 pka zen-2(e2500).
NJ654 rhDf1 III;sDp3 (III;f). C. elegans WT strain which throws WT and dead eggs. Sick and slow growing!!!

Alleles contributed by this laboratory

Allele Type DNA Change Protein Change
w40 Allele deletion
w34 Allele substitution nonsense
w13 Allele substitution splice_site
w37 Allele
w35 Allele