Laboratory Information
| Name | IZ View on WormBase |
|---|---|
| Allele designation | uf |
| Head | Michael M Francis |
| Institution | University of Massachusetts, Worcester, MA |
| Address | University of Massachusetts Medical School 364 Plantation Street LRB770V Department of Neurobiology Worcester 01605 United States |
| Website | http://www.umassmed.edu/mfrancislab/ |
| Gene classes |
Strains contributed by this laboratory
| Strain | Genotype | Species | Description |
|---|---|---|---|
| IZ1152 | ufIs104. | C. elegans | ufIs104 [nlp-12(+) + lgc-11p::GFP]. ufIs104 contains a 1.76 kb PCR product containing the nlp-12 genomic locus (−354 bp to +1407 bp relative to the transcriptional start). Over-expression of nlp-12 results in increased body bend amplitude. This strain has a high rate of sterility but can be successfully maintained as a homozygote. Reference: Bhattacharya R, et al. PLoS Genet. 2014 Aug 28;10(8):e1004584. doi: 10.1371/journal.pgen.1004584. PMID: 25167143. |
| IZ1458 | ufIs126 V. | C. elegans | ufIs126 [flp-13p::acr-12::GFP + lgc-11::mCherry] V. ACR-12::GFP expression labels postsynaptic iAChRs in DD motor neurons. References: Philbrook A, et al. eLife. 2018 Jul 24;7:e35692. doi: 10.7554/eLife.35692. PMID: 30039797. Oliver D, et al. PLoS Genet. 2022 Jan 28;18(1):e1010016. doi: 10.1371/journal.pgen.1010016. PMID: 35089924. Alexander K, et al. bioRxiv 2022.10.21.512874; doi: https://doi.org/10.1101/2022.10.21.512874. |
| PHX7515 | dve-1(syb7515[dve-1::AID*::mScarlet]) X. | C elegans | AID*::mScarlet tag inserted into endogenous dve-1 locus via CRISPR/Cas9 engineering. Reference: Alexander, K.D. et al. Nat Commun 2023 Nov 18;14(1):7520. PMID: 37980357. |
This laboratory hasn't submitted any alleles to the CGC.