Laboratory Information

NameIC View on WormBase
Allele designationqu
HeadIan D Chin-Sang
InstitutionQueen's University, Kingston, ON, Canada
Address Queen's University
Department of Biology
116 Barrie St.
Kingston K7L 3N6
Gene classes afd  nck 

Strains contributed by this laboratory

Strain Genotype Species Description
CZ4111 vab-2(ju1) IV. C. elegans vab-2(ju1) has embryonic lethality (12%) and notched heads (about 40%). vab-2(ju1) is considered a null allele (W30opal). pka efn-1.
IC136 zdIs5 I; vab-1(dx31) II. C. elegans zdIs5 [mec-4p::GFP + lin-15(+)] I. Animals contain GFP expressed in the touch neurons and have a notched head phenotype.
IC156 zdIs5 I; quIs4. C. elegans zdIs5 [mec-4p::GFP + lin-15(+)] I. quIs4 [mec-4::myr::vab-1(G912E) + rol-6(su1006)]. Animals contain GFP expressed in the touch neurons.
IC361 vab-1(e2)/mIn1 [dpy-10(e128) mIs14] II; sax-3(ky123) X. C. elegans Heterozygotes are WT and GFP+. mIn1 homozygotes are Dpy and GFP+. vab-1; sax-3 homozygotes are synthetic lethal.
IC400 zdIs5 I; quIs5 II; him-5(e1490) V. C. elegans zdIs5 [mec-4p::GFP + lin-15(+)] I. quIs5 [mec-4::myr::vab-1 + rol-6(su1006)]. Animals contain GFP expressed in the touch neurons.
IC459 sax-3(ky123) X; quEx102. C. elegans quEx102[F25B3.3::SAX-3 + odr-1::RFP]. F25B3.3::SAX-3 partially rescues the lethality and notch phenotype of sax-3(ky123). Maintain by picking RFP+.
IC464 sax-3(ky123) X; quEx100. C. elegans quEx100 [ajm-1::sax-3 + odr-1::RFP]. ajm-1::sax-3 partially rescues the lethality of sax-3(ky123). Maintain by picking RFP+.
IC476 sax-3(ky123) X; quEx99. C. elegans quEx99 [sax-3(minigene) + odr-1::RFP]. Rescues the lethality of ky123. Pick RFP+ to maintain.
IC611 quEx128. C. elegans quEx128 [npr-9::GFP + rol-6(su1006)]. Maintain by picking Rollers. ZK455.3 is npr-9 and is expressed in AIB neuron.
IC683 npr-9(tm1652) X. C. elegans
IC692 quEx162. C. elegans quEx162 [sax-3p::GFP + rol-6(su1006)]. Pick GFP to maintain. Very bright GFP in early embryos (after 24 cell stage). Not all GFP+ worms are rolling.
IC699 sax-3(ky123) ; quEx168. C. elegans quEx168 [sax-3::GFP + odr-1::RFP]. Pick RFP+ to maintain. GFP is visible at higher magnification but fades quickly. Strongest GFP is in the head region. The Chin-Sang Lab recommends researchers use this strain instead of IC450, as sax-3::GFP expression in IC699 is more consistent than in the comparable strain IC450.
IC700 juIs73 II; vab-2(ju1) IV. C. elegans juIs73 [unc-25p::GFP] II.
IC765 npr-9(tm1652) X; quEx182. C. elegans quEx182 [npr-9(+) + sur-5::GFP + odr-1::RFP]. Maintain by picking GFP+. Rescuing npr genomic fragment co-injected with sur-5::GFP and odr-1::RFP]. transgenic (GFP+) animals tend to wander off the food.
This laboratory hasn't submitted any alleles to the CGC.