Laboratory Information

NameHY View on WormBase
Allele designationye
HeadRaffi Van Aroian
InstitutionUniversity of Massachusetts Medical School
Address University of Massachusetts Medical School
BioTech 2, Suite 219
373 Plantation Street
Worcester 01605
United States
Website http://www.umassmed.edu/aroianlab/
Gene classes bre  brt  cor  hpo  pod  trb  ttm  scvp 

Strains contributed by this laboratory

Strain Genotype Species Description
HY463 unc-32(e189) pod-1(ye11)/qC1 [dpy-19(e1259) glp-1(q339)] III. C. elegans Heterozygotes are WT and segregate WT, Sterile Dpys and Uncs. Unc worms produce only dead embyros due to strict maternal effect pod-1(ye11) mutation. Embryos from pod-1 homozygous hermaphrodites are osmotically sensitive and exhibit polarity defects.
HY483 bre-3(ye26) III. C. elegans Resistant to Cry5B Bt toxin.
HY485 bre-4(ye27) IV. C. elegans Resistant to Cry5B Bt toxin. See also WBPaper00004776.
HY494 bre-2(ye31) III. C. elegans Resistant to Cry5B Bt toxin. Reduced brood size.
HY496 bre-1(ye4) IV. C. elegans Resistant to Cry5B Bt toxin. Reduced brood size.
HY498 bre-5(ye17) I. C. elegans Resistant to Cry5B Bt toxin.
HY520 pod-2(ye60) II. C. elegans Cold sensitive embryonic lethal. 95% viable at 24C, 3.7% viable at 15C. 43% symmetric 2-cell. Osmotically senstive (thus requires lineage in osmotically conditioned media, such as 0.8X egg salt).
HY601 mat-3(or344) III. C. elegans Temperature-sensitive embryonic lethal, maintain at 15C. Shift L4 hermaphrodites to 25C overnight for mutant embryos. Mutant embryos are sensitive to osmolarity and pressure. Previously called pod-4(or344).
HY604 mat-1(ye121) I. C. elegans Temperature-sensitive embryonic lethal, maintain at 15C. Shift L4 hermaphrodites to 25C overnight for mutant embryos. Mutant embryos are sensitive to osmolarity and pressure. Previously called pod-5(ye121).
HY607 apc-1(or319) II. C. elegans Temperature-sensitive embryonic lethal, maintain at 15C. Shift L4 hermaphrodites to 24C overnight for mutant embryos. Mutant embryos are sensitive to osmolarity and pressure. Previously called pod-3 and mat-2.
HY618 apc-1(or374) II; him-5(e1490) V. C. elegans Temperature-sensitive embryonic lethal, maintain at 15C. Shift L4 hermaphrodites to 25C overnight for mutant embryos. Mutant embryos are sensitive to osmolarity and pressure. Previously called pod-3 and mat-2..
HY619 apc-1(or385) II; him-5(e1490) V. C. elegans Temperature-sensitive embryonic lethal, maintain at 15C. Shift L4 hermaphrodites to 25C overnight for mutant embryos. Mutant embryos are sensitive to osmolarity and pressure. Previously called pod-3 and mat-2.
HY621 emb-27(ye143) II. C. elegans Temperature-sensitive embryonic lethal, maintain at 15C. Shift L4 hermaphrodites to 25C overnight for mutant embryos. Mutant embryos are sensitive to osmolarity and pressure. Previously called pod-6(ye143).

Alleles contributed by this laboratory

Allele Type DNA Change Protein Change
ye11 Allele
ye26 Allele
ye27 Allele
ye31 Allele substitution
ye4 Allele substitution
ye17 Allele substitution nonsense
ye60 Allele
ye121 Allele substitution
ye143 Allele