Laboratory Information
| Name | HY View on WormBase |
|---|---|
| Allele designation | ye |
| Head | Raffi Van Aroian |
| Institution | University of Massachusetts Medical School |
| Address | University of Massachusetts Medical School BioTech 2, Suite 219 373 Plantation Street Worcester 01605 United States |
| Website | http://www.umassmed.edu/aroianlab/ |
| Gene classes | bre brt cor hpo pod trb ttm scvp |
Strains contributed by this laboratory
| Strain | Genotype | Species | Description |
|---|---|---|---|
| HY123 | nhr-31(ye123) IV. | C. elegans | Maintain at 15C. Temperature-sensitive: slow growth rate, reduced brood size. Resistant to Cry proteins. Isolated from EMS screen in N2 background. Reference: Kim YM, et al. PLoS Pathog. 2024 Oct 18;20(10):e1012611. doi: 10.1371/journal.ppat.1012611. PMID: 39423230. |
| HY463 | unc-32(e189) pod-1(ye11)/qC1 [dpy-19(e1259) glp-1(q339)] III. | C. elegans | Heterozygotes are WT and segregate WT, Sterile Dpys and Uncs. Unc worms produce only dead embyros due to strict maternal effect pod-1(ye11) mutation. Embryos from pod-1 homozygous hermaphrodites are osmotically sensitive and exhibit polarity defects. |
| HY483 | bre-3(ye26) III. | C. elegans | Resistant to Cry5B Bt toxin. |
| HY485 | bre-4(ye27) IV. | C. elegans | Resistant to Cry5B Bt toxin. See also WBPaper00004776. |
| HY494 | bre-2(ye31) III. | C. elegans | Resistant to Cry5B Bt toxin. Reduced brood size. |
| HY496 | bre-1(ye4) IV. | C. elegans | Resistant to Cry5B Bt toxin. Reduced brood size. |
| HY498 | bre-5(ye17) I. | C. elegans | Resistant to Cry5B Bt toxin. |
| HY520 | pod-2(ye60) II. | C. elegans | Cold sensitive embryonic lethal. 95% viable at 24C, 3.7% viable at 15C. 43% symmetric 2-cell. Osmotically senstive (thus requires lineage in osmotically conditioned media, such as 0.8X egg salt). |
| HY601 | mat-3(or344) III. | C. elegans | Temperature-sensitive embryonic lethal, maintain at 15C. Shift L4 hermaphrodites to 25C overnight for mutant embryos. Mutant embryos are sensitive to osmolarity and pressure. Previously called pod-4(or344). |
| HY604 | mat-1(ye121) I. | C. elegans | Temperature-sensitive embryonic lethal, maintain at 15C. Shift L4 hermaphrodites to 25C overnight for mutant embryos. Mutant embryos are sensitive to osmolarity and pressure. Previously called pod-5(ye121). |
| HY607 | apc-1(or319) II. | C. elegans | Temperature-sensitive embryonic lethal, maintain at 15C. Shift L4 hermaphrodites to 24C overnight for mutant embryos. Mutant embryos are sensitive to osmolarity and pressure. Previously called pod-3 and mat-2. |
| HY618 | apc-1(or374) II; him-5(e1490) V. | C. elegans | Temperature-sensitive embryonic lethal, maintain at 15C. Shift L4 hermaphrodites to 25C overnight for mutant embryos. Mutant embryos are sensitive to osmolarity and pressure. Previously called pod-3 and mat-2.. |
| HY619 | apc-1(or385) II; him-5(e1490) V. | C. elegans | Temperature-sensitive embryonic lethal, maintain at 15C. Shift L4 hermaphrodites to 25C overnight for mutant embryos. Mutant embryos are sensitive to osmolarity and pressure. Previously called pod-3 and mat-2. |
| HY621 | emb-27(ye143) II. | C. elegans | Temperature-sensitive embryonic lethal, maintain at 15C. Shift L4 hermaphrodites to 25C overnight for mutant embryos. Mutant embryos are sensitive to osmolarity and pressure. Previously called pod-6(ye143). |
Alleles contributed by this laboratory
| Allele | Type | DNA Change | Protein Change |
|---|---|---|---|
| ye11 | Allele | ||
| ye26 | Allele | ||
| ye27 | Allele | ||
| ye31 | Allele | substitution | |
| ye4 | Allele | substitution | |
| ye17 | Allele | substitution | nonsense |
| ye60 | Allele | ||
| ye121 | Allele | substitution | |
| ye143 | Allele |