Laboratory Information

NameGMC View on WormBase
Allele designationgmc
HeadGawain McColl
InstitutionThe Florey Institute of Neuroscience
Address University of Melbourne
30 Royal Parade
Parkville 3052
Australia
Website https://www.florey.edu.au/node/595
Gene classes

Strains contributed by this laboratory

Strain Genotype Species Description
GMC101 dvIs100. C. elegans dvIs100 [unc-54p::A-beta-1-42::unc-54 3'-UTR + mtl-2p::GFP]. mtl-2p::GFP produces constitutive expression of GFP in intestinal cells. unc-54p::A-beta-1-42 expresses full-length human A-beta-1-42 peptide in bodywall muscle cells that aggregates in vivo. Shifting L4 or young adult animals from 20C to 25C causes paralysis. Reference: McColl G, et al. Mol Neurodegener. 2012 Nov 21;7:57.
This laboratory hasn't submitted any alleles to the CGC.