Laboratory Information

NameGMC View on WormBase
Allele designationgmc
HeadGawain McColl
InstitutionThe Florey Institute of Neuroscience
Address University of Melbourne
30 Royal Parade
Parkville 3052
Gene classes

Strains contributed by this laboratory

Strain Genotype Species Description
GMC101 dvIs100. C. elegans dvIs100 [unc-54p::A-beta-1-42::unc-54 3'-UTR + mtl-2p::GFP]. mtl-2p::GFP produces constitutive expression of GFP in intestinal cells. unc-54p::A-beta-1-42 expresses full-length human A-beta-1-42 peptide in bodywall muscle cells that aggregates in vivo. Shifting L4 or young adult animals from 20C to 25C causes paralysis. Reference: McColl G, et al. Mol Neurodegener. 2012 Nov 21;7:57.
This laboratory hasn't submitted any alleles to the CGC.