Laboratory Information
| Name | GB View on WormBase |
|---|---|
| Allele designation | sf |
| Head | Guy M Benian |
| Institution | Emory University, Atlanta, GA |
| Address | Department of Pathology, Emory University Whitehead Biomedical Research Building, room 105E 615 Michael Street Atlanta 30322 United States |
| Website | http://pathology.emory.edu/AdminFacultyMember.cfm?Name_seq=6 |
| Gene classes | cpna duox pkn scpl ttn |
Strains contributed by this laboratory
| Strain | Genotype | Species | Description |
|---|---|---|---|
| GB244 | unc-96(sf18) X. | C. elegans | Adults are Unc - reduced motility; characteristic birefrigent "needles" in body wall muscle cells by polarized light microscopy; contain accumulations of paramyosin and UNC-98. Phenotype (needles and accumulations of paramyosin) is suppressed by growth at 15C or by starvation. |
| GB246 | unc-98(sf19) X. | C. elegans | Adults are Unc - reduced motility; characteristic birefrigent "needles" in body wall muscle cells by polarized light microscopy; contain accumulations of paramyosin and UNC-96. |
| GB247 | unc-94(sf20) I. | C. elegans | Adults are Unc - reduced motility; disorganization of myofilament lattice in body wall muscle cells by polarized light microscopy; abnormal accululations of F-actin near muscle cell-cell boundaries. |
| GB296 | sfIs21. | C. elegans | sfIs21 [myo-3p::PercevalHR + lin-44p::GFP]. Reporter can be used to measure the ATP/ADP ratio in body wall muscle cells. Matsunaga Y, et al. Commun Biol. 2024 Oct 17;7(1):1342. doi: 10.1038/s42003-024-07042-3. PMID: 39420071. |
Alleles contributed by this laboratory
| Allele | Type | DNA Change | Protein Change |
|---|---|---|---|
| sf18 | Allele | substitution | |
| sf19 | Allele | substitution | splice_site |
| sf20 | Allele | substitution | nonsense |