Caenorhabditis Genetics Center (CGC)

Laboratory Information

NameEM View on WormBase
Allele designationbx
HeadScott Wilson Emmons
InstitutionAlbert Einstein College of Medicine, Bronx, NY
Address Albert Einstein College of Medicine
Ullmann 703
1300 Morris Park Ave
Bronx 10461
United States
Website http://worms.aecom.yu.edu./
Gene classes cwp  his  ngn  rax  sop 

Strains contributed by this laboratory

Strain Genotype Species Description
CB3912 eT2 (X;I)/unc-2(e55) X. C. elegans Heterozygotes are WT and segregate WT, Unc and dead embryos. eT2 homozygotes are embryonic lethals.
CB4111 mab-24(e2169) I; him-5(e1490) V. C. elegans Anterior displacement of rays and fan. Ray identities are not altered. Slightly Unc (coiler).
DF5006 Rhabditella axei wild isolate. Rhabditella axei 0006. Rhabditella axei. Male/Female strain. Isolated by W. Sudhaus on July 29, 1979 from a compost heap in Esmoulieres, France. Grown easily on OP50 at 16-25C. See WBG 12(5) 14.
DF5012 Rhomborhabditis regina wild isolate. Rhomborhabditis regina 0012. Male/Female strain. Isolated by M. Velasquez in the spring of 1989 from a June beetle larva (Scarabaeidae) near Quetzaltenango, Guatemala. WBG 12(5) 14. Formerly known as Rhabditoides regina.
DF5013 Pelodera strongyloides wild isolate. Pelodera strongyloides 0013. Pelodera strongyloides. Male/Female strain. See WBG 12(5) 14. Originally came from Sudhaus.
DF5017 Mesorhabditis longespiculosa wild isolate. Mesorhabditis longespiculosa WT strain. Mesorhabditis longespiculosa. Isolated by W. Sudhaus on August 16, 1973 from tunnels of beetle larvae (Mallodon downesi?, Cerambycidae) in Euphorbiaceae at lake Nakuru, Kenya. See WBG 12(5) 14. Male/Female strain.
DF5018 Oscheius dolichuroides wild isolate. Oscheius dolichuroides WT strain. Rhabditis (Oscheius) dolichuroides. Isolated by W. Sudhaus in April 1978 from decaying matter in a hole in a tree in Malindi, Kenya. See WBG 12(5) 14. Male/Female strain.
DF5019 Teratorhabditis palmarum wild isolate. Teratorhabditis palmarum Robin Giblin-Davis MUST be cited in any publication. Isolated by R. Giblin-Davis from the palm weevil Rhynchphorus cruentatus (Curculionidae) in Broward County, Florida. Male/Female strain. See WBG 12(5) 14.
DF5020 Oscheius myriophilus wild isolate. Oscheius myriophilus 0020. Formerly known as Rhabditis (Rhabditis) myriophila. Taxonomy ID: 281680 Isolated by G. O. Poiner (see Poiner, 1986).
DF5025 Reiterina typica wild isolate. Reiterina typica WT strain. Rhabditis (Pellioditis) typica. Male/Female strain. Isolated by W. Sudhaus on Sept. 3, 1973 from feces of an antelope in Tsavo National Park, Kenya. See WBG 12(5) 14. Formerly known as Rhabditis (Pellioditis) typica.
DF5033 Oscheius sp. wild isolate. Oscheius dolichura WT strain. Oscheius sp. See WBG 12(5) 14. Male/Female strain. Collected by a Belgian expedition to the Galapagos archipelago. From Gaetan Borgonie, Gent University, Belgium.
DF5040 Pelodera strongyloides wild isolate. Pelodera strongyloides Male/Female strain. Pelodera strongyloides. See WBG 12(5) 14. Originally came from Victor Ambros.
EM101 lin-41(bx37) I; him-5(e1490) V. C. elegans Maintain under normal conditions. Males have long tail tips.
EM105 mab-21(bx41) III; him-5(e1490) V. C. elegans Transformation of ray 6 to a thin ray which is anteriorly displaced and fuses with ray 4 (95%). A 10th ray is found in about 50% of the sides scored. Body is slightly shorter.
EM106 lin-41(bx42) I; him-5(e1490) V. C. elegans Maintain under normal conditions. Males have long tail tips.
EM111 him-5(e1490) V; mab-19(bx38) X. C. elegans Male phenotype: loss of rays 7-9; incomplete penetrance/expressivity (80%); T lineage defect. Hermaphrodite phenotype: lowered brood size (100 progeny/hermaphrodite). Hypomorphic allele: uDf1/mab-19(bx38) results in embryonic arrest during morphogenesis.
EM113 dpy-10(e128) ram-2(bx32) II; him-5(e1490) V. C. elegans Dpy. Abnormal rays.
EM116 mab-25(bx27) I; him-5(e1490) V. C. elegans Temperature sensitive. Missing Ray. Swollen tail and reduced fan. Temperature sensitive lethal at all stages. Wrinkled spicule.
EM122 stDp2 (X;II)/+ II; him-5(e1490) V; unc-18(e81) dpy-6(e14) X. C. elegans Strain throws WT, DpyUncs and males (and some Lon-don't know where these come from??). Maintain by picking WT. non-Unc non-Dpy males mate at low frequency and will transmit stDp2.
EM128 mab-21(bx53) III; him-5(e1490) V. C. elegans Transformation of ray 6 to a thin ray which is anteriorly displaced and fuses with ray 4 (95%). A 10th ray is found in about 50% of the sides scored. Slightly shorter than WT. mab-21(bx53)/yDf10 is embryonically lethal with embryo arrest at 2 fold stage.
EM131 ram-2(bx39) II; him-5(e1490) V. C. elegans Lumpy rays.
EM139 ram-1(bx34) I; him-5(e1490) V. C. elegans Lumpy rays.
EM140 dpy-5(e61) ram-1(bx34) I; him-5(e1490) V. C. elegans Dpy. Rays abnormal.
EM141 unc-17(e113) col-34(bx25) IV; him-5(e1490) V. C. elegans Unc. Abnormal rays. bx25 previously called ram-4.
EM146 dpy-10(e128) ram-2(bx39) II; him-5(e1490) V. C. elegans Dpy. Abnormal rays.
EM172 unc-4(e120) II; him-5(e1490) V; lin-32(bx46) X. C. elegans Missing Rays. Unc.
EM185 tra-1(e1099) III; ram-5(bx30) X; eDp6 (III;f). C. elegans Animals with the duplication are WT. XX Animals which have lost the duplication are males (low fertility-gonad morphology variable). Rays abnormal. See also WBPaper0000498.
EM207 tbx-2(bx59) III; him-5(e1490) V. C. elegans Conditional lethal: inviable when grown at 25C. Wild type at 16C. Viable when grown at 20C; partial ray loss at 20C. Shifting males during ray assembly to non-permissive temperature results in ray loss. No lineage defect.
EM253 mab-20(bx61) I; him-5(e1490) V. C. elegans Ray 3 and 4 fusion >60% at non-permissive temp. Ray 1 and 2 fusion about 10% at non-permissive temp. ts period is around L3-L4.
EM305 efn-4(bx80) IV; him-5(e1490) V. C. elegans Extensive ray fusion involving all 9 rays. Larva have Vab phenotype with decreasing expressivity in adult. Hermaphrodites have swollen tail and anus. bx80 pka mab-26(bx80).
EM331 him-5(e1490) V; mab-19(bx83) X. C. elegans Male phenotype: loss of rays 7-9; incomplete penetrance/expressivity (80%); T lineage defect. Hermaphrodite phenotype: lowered brood size (100 progeny/hermaphrodite). Hypomorphic allele: uDf1/mab-19(bx83) results in embryonic arrest during morphogenesis.
EM434 Pellioditis pelhamensis wild isolate. Pellioditis pelhamensis WT strain, Pellioditis pelhamensis. See WBG 12(5)14. Male/Female strain. Previously and incorrectly called Rhabditis maupasi by the CGC. Also previously called DF5039.
EM437 Pelodera teres wild isolate. Pelodera teres WT strain, Pelodera teres. See WBG 12(5) 14. Male/Female strain. Previously called DF5016.
EM464 C. remanei ssp. vulgaris C. remanei ssp. vulgaris Male-female strain. Reference WBG 11(4):89. See also WBPaper00001874. May crawl off the plates. Previously called C. vulgaris BK and C. vulgariensis BK. Walter Sudhaus has tentatively described this strain as C. remanei ssp. vulgaris; this description is not official and is contigent upon its being published. See WBPaper00002633 and WBPaper00003993.
EM489 pal-1(e2091) III; him-5(e1490) V; dpy-22(bx92) X. C. elegans V6 produces rays instead of alae in pal-1; sop01 mutants. No obvious phenotype in a pal-1(+) background. Previously called sop-1(bx92).
EM490 pal-1(e2091) III; him-5(e1490) V; dpy-22(bx93) X. C. elegans V6 produces rays instead of alae in pal-1; sop01 mutants. No obvious phenotype in a pal-1(+) background. Previously called sop-1(bx93).
EM493 sop-3(bx96) I; pal-1(e2091) III; him-5(e1490) V. C. elegans V6 produces rays instead of alae in sop-3; pal-1 mutants.
EM496 hlh-2(bx108) I; him-5(e1490) V; lin-32(e1926) X. C. elegans Males are rayless. hlh-2(bx108) strongly and semi-dominantly enhances the ray-loss phenotype of lin-32(e1926).
EM507 pal-1(e2091) III; him-5(e1490) V; dpy-22(bx103) X. C. elegans V6 produces rays instead of alae in pal-1; sop-1 mutants. No obvious phenotype in a pal-1(+) background. Previously called sop-1(bx103).
EM511 pal-1(e2091) III; him-5(e1490) V; dpy-22(bx107) X. C. elegans V6 produces rays instead of alae in pal-1; sop01 mutants. No obvious phenotype in a pal-1(+) background. Previously called sop-1(bx107).
EM598 hlh-2(bx115) unc-13(e51) I; him-5(e1490) V. C. elegans Paralyzed Unc. Throws males. hlh-2(bx115) has no phenotype in this background.
EM599 him-5(e1490) V; lin-15B&lin-15A(n765) X; bxIs13. C. elegans bxIs13 [egl-5::GFP + lin-15(+)]. Him. egl-5::GFP reporter made from EM#286 (GFP inserted within the last few amino acids of the C-terminus) by integrating bxEx30 in EM588. High nuclear expression of transgene in males (good in seam cells, none in rectal epithelium), weak expression in hermaphrodites. Expression in 2-4 head neurons in males and hermaphrodites. egl-5 gene on reporter does not rescue egl-5(-).
EM62 mab-17(e2167) unc-15(e73) I; him-5(e1490) V. C. elegans Unc. Round bulging adult male tale. Very reduced fan. Mating efficiency is zero.
EM66 him-5(e1490) V; vab-3(bx23) X. C. elegans Transformation of ray 6 to a thin ray which is anteriorly displaced and fuses with ray 4 (99%). Body is slightly shorter. See also WBPaper00002235.
EM67 mab-20(bx24) I; him-5(e1490) V. C. elegans Extensive ray fusion. Posterior portion of body swollen at larval stages.
EM68 col-34(bx25) IV; him-5(e1490) V. C. elegans Lumpy rays. Temperature sensitive. bx25 previously called ram-4.
EM723 sop-2(bx91) II; him-5(e1490) V. C. elegans Temperature sensitive. Early larval arrest at 25C. At 20C, Lon, PVul, Muv, Mog, ectopic Hox gene expression.
EM81 him-5(e1490) V; ram-5(bx30) X. C. elegans Lumpy rays.
EM886 rax-2(bx131) III; bxIs14 him-5(e1490) V. C. elegans bxIs14 [pkd-2::GFP + pdx-1]. Ray axon defective.
EM902 madd-2(bx132) bxIs14 him-5(e1490) V. C. elegans bxIs14 [pkd-2::GFP + pdx-1]. Ray axon defective.
EM905 rax-5(bs137) II; bxIs14 him-5(e1490) V. C. elegans bxIs14 [pkd-2::GFP + pdx-1]. Ray axon defective.
EM907 rax-3(bx133) I; bxIs14 him-5(e1490) V. C. elegans bxIs14 [pkd-2::GFP + pdx-1]. Ray axon defective.
EM908 rax-3(bx138) I; bxIs14 him-5(e1490) V. C. elegans bxIs14 [pkd-2::GFP + pdx-1]. Ray axon defective.
EM909 rax-4(bx139) I; bxIs14 him-5(e1490) V. C. elegans bxIs14 [pkd-2::GFP + pdx-1]. Ray axon defective.
EM911 rax-6(bx140) IV; bxIs14 him-5(e1490) V. C. elegans bxIs14 [pkd-2::GFP + pdx-1]. Ray axon defective.
EM97 ram-2(bx32) II; him-5(e1490) V. C. elegans Lumpy rays.
MT691 nDf7/unc-93(e1500) dpy-17(e164) III. C. elegans Hets are Unc(Rubberband) and Egl. Segregate Unc, DpyUnc and early larval lethals (L1). Maintain by picking Uncs. Received new stock 1/3/94.
MT692 nDf8/unc-93(e1500) dpy-17(e164) III. C. elegans Hets are Unc(Rubberband) and Egl. Segregate Unc, DpyUnc, and dead eggs. Maintain by picking Uncs.
MT696 nDf12/unc-93(e1500) dpy-17(e164) III. C. elegans Hets are Unc (Rubberband) and Egl. Segregate Unc, DpyUnc and dead eggs. Maintain by picking Uncs. CGC received new stock 8/98.
PS611 mab-21(sy155) III; him-5(e1490) V. C. elegans Transformation of ray 6 to a thin ray which is anteriorly displaced and fuses with ray 4 (95%). A 10th ray is found in about 50% of the sides scored. Body is slightly shorter. Do not distribute this strain; other labs should request it from the CGC. This strain cannot be distributed to commercial organizations. This strain cannot be used for any commercial purpose or for work on human subjects.
VT733 C. remanei ssp. vulgaris C. remanei ssp. vulgaris Male-female strain. Reference WBG 11(4):89. See also WBPaper00001874. May crawl off the plates. Isolated by Bill Fixsen at a rest area on the turnpike in Conn. Previously called WS9-6 and C. vulgaris NH and C. vulgariensis by the CGC. Walter Sudhaus has tentatively described this strain as C. remanei ssp. vulgaris; this description is not official and is contigent upon its being published. See WBPaper00002633.

Alleles contributed by this laboratory

Allele Type DNA Change Protein Change
bx80 Allele deletion
bx85 Allele deletion frameshift
bx37 Allele substitution
bx41 Allele
bx42 Allele deletion
bx38 Allele
bx32 Allele
bx27 Allele
bx53 Allele
bx39 Allele
bx34 Allele
bx25 Allele
bx46 Allele
bx30 Allele
bx59 Allele substitution
bx61 Allele
bx83 Allele
bx92 Allele substitution nonsense
bx93 Allele substitution nonsense
bx96 Allele
bx108 Allele substitution
bx103 Allele substitution splice_site
bx107 Allele substitution nonsense
bx115 Allele substitution
bx23 Allele deletion
bx24 Allele
bx91 Allele substitution
bx131 Allele
bx132 Allele substitution nonsense
bx133 Allele
bx138 Allele
bx139 Allele
bx140 Allele
bx142 Allele substitution splice_site