Laboratory Information

NameDR View on WormBase
Allele designationm
HeadRiddle, Don
InstitutionGenome BC, Vancouver, BC, Canada
Address

Gene classes ama  ded  liv  misc  rpo  sus  tts  daf* 

Strains contributed by this laboratory

Strain Genotype Species Description
BC2021 let-289(s1133) unc-22(s7) unc-31(e169)/nT1 IV; +/nT1 V. C. elegans Heterozygotes are WT and segregate WT, Vuls, early larval lethals which are Unc and Twitch, and dead eggs. Maintain by picking WT. Not outcrossed!
BC2024 let-291(s1139) unc-22(s7) unc-31(e169)/nT1 IV; +/nT1 V. C. elegans Heterozygotes are WT and segregate WT, Vuls, early larval lethals which are Unc and Twitch, and dead eggs. Maintain by picking WT. Not outcrossed!
BC2034 let-292(s1146) unc-22(s7) unc-31(e169)/nT1 IV; +/nT1 V. C. elegans Heterozygotes are WT and segregate WT, Vuls, early larval lethals which are Unc and Twitch, and dead eggs. Maintain by picking WT. Not outcrossed!
BC2037 let-293(s1166) unc-22(s7) unc-31(e169)/nT1 IV; +/nT1 V. C. elegans Heterozygotes are short and somewhat Egl. Offspring are short. Segregate Vuls, early larval lethals which are Unc and Twitch, and dead eggs. Not outcrossed!
BC2047 let-290(s1140) unc-22(s7) unc-31(e169)/nT1 IV; +/nT1 V. C. elegans Heterozygotes are WT and segregate WT, Vuls, early larval lethals which are Unc and Twitch, and dead eggs. Maintain by picking WT. Not outcrossed!
BC2070 let-294(s1103) unc-22(s7) unc-31(e169)/nT1 IV; +/nT1 V. C. elegans Heterozygotes are WT and segregate WT, Vuls, early larval lethals which are Unc and Twitch, and dead eggs. Maintain by picking WT. Not outcrossed!
BC2088 let-295(s1175) unc-22(s7) unc-31(e169)/nT1 IV; +/nT1 V. C. elegans Heterozygotes are WT and segregate WT, Vuls, early larval lethals which are Unc and Twitch, and dead eggs. Maintain by picking WT. Not outcrossed!
BC2148 let-296(s1250) unc-22(s7) unc-31(e169)/nT1 IV; +/nT1 V. C. elegans Heterozygotes are WT and segregate WT, Vuls, early-mid larval lethals which are Unc and Twitch, and dead eggs. Maintain by picking WT. Not outcrossed!
BC3499 let-297(s1989) unc-22(s7) unc-31(e169)/nT1 IV; +/nT1 V. C. elegans Heterozygotes are WT and segregate WT, Vuls, early larval lethals which are Unc and Twitch, and dead eggs. Maintain by picking WT. Not outcrossed!
DR1 unc-101(m1) I. C. elegans Paralyzed coiler. Slightly Egl. Slightly short. About half do not survive to adulthood-arrest usually in L1. See also WBPaper00001868.
DR101 dpy-5(e61) unc-55(e1170) I. C. elegans Dpy. Unc. Closely Linked.
DR102 dpy-5(e61) unc-29(e403) I. C. elegans DpyUnc.
DR1056 unc-42(e270) ama-2(m323) V/nT1 [let-?(m435)] (IV;V). C. elegans Heterozygotes are WT and segregate WT and dead eggs. (Chromosome carrying unc-42 ama-2 is homozygous lethal.) Strain is resistant to _-amanitin.
DR106 unc-24(e1172) dpy-4(e1166) IV. C. elegans DpyUnc.
DR107 unc-26(e205) dpy-4(e1166) IV. C. elegans DpyUnc.
DR108 dpy-11(e224) unc-42(e270) V. C. elegans DpyUnc.
DR1089 unc-77(e625) IV. C. elegans Dominant loopy Unc with exaggerated sine wave.
DR1096 lon-1(e185) unc-36(e251) III. C. elegans Very long, thin, and slow moving.
DR1099 ama-1(m118m526) IV. C. elegans More resistant to alpha-amanitin than ama-1(m118). Will grow in the presence of 0.5% triton-X 100 with 100 ug/ml amanitin whereas ama-1(m118) will not. DR1099 displays temperature-sensitive defects consistent with defective RNA Pol II function. Sterile at 25C (maternal effect sterile). Fertile at 20C, but produces few viable progeny (~80% eggs that do not hatch). Periodically check for Emb to prevent spontaneously suppressed animals from taking over a population. Reference: Rogalski TM, et al. Genetics. 1990 Dec;126(4):889-98.
DR111 him-4(e1266) unc-3(e151) X. C. elegans Unc. Segregates males.
DR112 lon-2(e678) him-4(e1267) X. C. elegans Long. Segregates males.
DR116 unc-15(e73) I; sma-1(e30) V. C. elegans Small. Unc.
DR117 unc-15(e73) I; dpy-11(e224) V. C. elegans Dpy. Unc. Very slow movement.
DR1172 let-60(s59) unc-22(s7) IV/nT1 [let-?(m435)] (IV;V). C. elegans Heterozygotes are WT and segregate WT, Lethal Twitchers, and dead eggs. Lethal mid-larval (leaky). Maintain by picking WT. Heterozygotes twitch in 1% nicotine.
DR118 unc-15(e73) I; dpy-11(e224) eDp22 V. C. elegans
DR119 unc-54(e1258) I; dpy-11(e224) wdDp1 V. C. elegans DPY.
DR1191 daf-12(m20) unc-27(e155) egl-15(n484) X. C. elegans Dauer defective. Egl-60% form bags of worms. Unc-sluggish, poor backing. Resistant to both imipramine and serotonin. Slightly Dpy.
DR120 unc-54(e1258) I; eDp23 V. C. elegans
DR1213 unc-44(e362) unc-24(e138) IV. C. elegans Unc-44 masks the Unc-24 phenotype. Paralyzed coiler, Dpy, tends to curl.
DR1215 unc-22(s7) let-67(s214) IV/nT1 [let-?(m435)] (IV;V). C. elegans Heterozygotes are WT and segregate WT, dead eggs and Twitchers that arrest as larvae. Maintain by picking WT. Hets twitch in 1% nicotine.
DR1218 mnC1 [dpy-10(e128) unc-52(e444)]/unc-4(e120) let-265(mn188) II. C. elegans Heterozygotes are WT and segregate WT, DpyUnc, and Lethal Unc-4 (lethal mid-larval). Maintain by picking WT.
DR1228 unc-45(e286) daf-7(e1372) dpy-1(e1) III. C. elegans Dpy. Temperature sensitive dauer constitutive (leaky). Temperature sensitive Unc. At 15C, Dpy adults and some dauers. At 25C, DpyUnc dauers and some DpyUnc adults (leakiness varies: 60-95% dauers).
DR128 dpy-1(e1) daf-2(e1370) III. C. elegans Temperature sensitive dauer constitutive. Dpy. 100% dauers at 25C.
DR129 daf-2(e1370) unc-32(e189) III. C. elegans Temperature senstive dauer constitutive. Unc-coiler. 100% dauers at 25C.
DR1290 dpy-6(e14) unc-3(e151) X. C. elegans Medium sized Dpy which curls its tail.
DR130 dpy-1(e1) daf-2(e1370) unc-32(e189) III. C. elegans Temperature sensitive dauer constitutive. 100% dauers at 25C. Dpy. Unc-coiler. Reference strain for daf-2 complementation.
DR1309 daf-16(m26) I; daf-2(e1370) III. C. elegans
DR133 daf-7(e1372) dpy-1(e1) unc-32(e189) III. C. elegans Temperature sensitive dauer constitutive. 100% dauers at 25C. Dpy. Unc-coiler. Reference strain for daf-7 complementation.
DR1367 bli-6(sc16) mec-3(e1338) IV. C. elegans Blistered. Mechanosensory abnormal.
DR1369 sma-4(e729) III. C. elegans Short, non-Dpy. Males have crumpled spicules.
DR137 dpy-5(e61) daf-8(e1393) I. C. elegans Temperature sensitive dauer constitutive. Dpy.
DR138 che-3(e1378) I; dpy-13(e184) IV. C. elegans Dauer defective. Dpy.
DR139 che-3(e1379) I; dpy-13(e184) IV. C. elegans Dauer defective. Dpy.
DR1408 daf-16(m26) I; age-1(m333) II. C. elegans Egl phenotype, viable. Lethality and Daf-c phenotype of m333 suppressed by daf-16 (m333 alone is a maternal-effect non-conditional dauer constitutive). age-1(m333) pka daf-23(m333).
DR1410 dpy-27(y56)/qC1 [dpy-19(e1259) glp-1(q339)] III. C. elegans WT strain which segregates WT, Dpy and DpySteriles (or WT Steriles if grown at 15C.) Maintain by picking WT. dpy-27 animals are mildly Dpy and Egl with protruding vulva. Maternal effect: dpy-27 homozygotes from het parent give severe Dpy hermaphrodites which are marginally viable and give more severe Dpy hermaphrodites and WT males. Males are vigorous and mate well. See also WBPaper00002061.
DR1564 daf-2(m41) III. C. elegans Temperature-sensitive dauer-consitutive, long-lived, intrinsically thermotolerant. Adults slightly shorter than adults of other daf-2 alleles. Up to 6% of L1s arrest at 25.5C. Makes nearly 100% dauers at 25C, 0% dauers at 15C. Good recovery of dauers at 15C.
DR168 unc-13(e51) daf-8(e1393) I. C. elegans Temperature sensitive dauer constitutive. Unc. Semi-paralyzed. Closely linked.
DR169 che-3(e1378) I; unc-5(e53) IV. C. elegans Dauer defective. Unc-coiler.
DR170 unc-5(e53) IV; che-2(e1033) X. C. elegans Dauer defective. Unc-coiler.
DR1720 unc-4(e120) daf-19(m86) II. C. elegans Unc. Dauer constitutive.
DR176 unc-54(e190) I; eDp23 V. C. elegans Suppressed-movement slow. Unlinked double.
DR177 unc-54(e1258) I; eDp22 V. C. elegans Suppressed-movement slow.
DR1785 mIn1 [dpy-10(e128)]/unc-4(e120) II. C. elegans WT phenotype. Segregates WT, homozygous Dpy-10 mIn1 and homozygous Unc-4 hermaphrodites. Recombination in this interval is suppressed, and recombinant animals have not been detected in this stock. This strain was generated by the Genetic Toolkit project, which should be acknowledged in any publications resulting from its use: The Genetic Toolkit is funded by the NIH National Center for Research Resources (NCRR) (USA) to Ann M. Rose, David L. Baillie, and Donald L. Riddle. Report all experimental results to Don Riddle. mIn1 pka mC6.
DR1786 dpy-13(e184) unc-24(e138) IV; mDp4[unc-17(e245)] (IV;?). C. elegans WT phenotype. Segregates WT and DpyUncs. mDp4 carries dpy-13(+) and unc-24(+). Duplication may recombine with normal homologues. Presence of unc-17(e245) on mDp4 confirmed: got Unc-17 segregants after heat shock of this stock to generate males. Pick WT and check for segregation of progeny to maintain.
DR1790 rol-1(e91)/mT1 II; unc-71(e541)/mT1 [dpy-10(e128)] III. C. elegans Heterozygotes are WT and segregate WT, Roller Uncs, and a few Dpy mT1 homozygotes. mT1 is an apparent II;III translocation: small broods, lots of dead eggs, and exhibits pseudolinkage between rol-1 II and unc-71 III. The Roller phenotype of rol-1 expresses late and cannot be scored before adulthood. Pick non-Unc hermaphrodites and check for correct segregation of progeny.
DR1799 daf-7(n696)/unc-45(st604) III. C. elegans WT phenotype. Segregates WT, constitutive dauers and ts mild Uncs. Uncs are maternal-effect lethal: F1 Uncs from a heterozygote produce only arrested 2-fold stage progeny that hatch. Grow at 22.5C (n696 produces nearly 100% dauers at this temperature).
DR1809 mIn1 [dpy-10(e128) let-?(m727)]/unc-4(e120) II. C. elegans Heterozygotes are WT and segregate WT, unc-4, and lethal mIn1 homozygotes. Pick WT and check for correct segregation of progeny.
DR181 unc-60(m35) dpy-11(e224) V. C. elegans Dpy. Unc-slow moving.
DR183 dpy-11(e224) daf-11(m47) V. C. elegans Temperature sensitive dauer constitutive. Dpy.
DR1832 mT1/unc-4(e120) II; mT1 [dpy-10(e128)]/dpy-17(e164) III. C. elegans WT phenotype. Segregates WT, sterile Dpy mT1 homozygotes, Unc-4;Dpy-17 and large numbers of arrested aneuploid embryos. Pick WT and check for correct segregation of progeny to maintain. This strain was generated by the Genetic Toolkit project, which should be acknowledged in any publications resulting from its use: The Genetic Toolkit is funded by the NIH National Center for Research Resources (NCRR) (USA) to Ann M. Rose, David L. Baillie, and Donald L. Riddle. Report all experimental results to Don Riddle.
DR184 daf-8(e1393) I; daf-10(e1387) IV. C. elegans Temperature sensitive dauer constitutive. Dauer recovery poor at 15C.
DR185 dpy-13(e184) unc-22(m52) IV. C. elegans Dominant Twitcher Unc. Semi-dominant Dpy.
DR188 daf-11(m47) unc-76(e911) V. C. elegans Temperature sensitive dauer constitutive. Dauer recovery poor at 15C. Unc.
DR189 dpy-5(e61) daf-8(e1393) unc-29(e1072) I. C. elegans Temperature sensitive dauer constitutive. Dpy. Unc.
DR190 dpy-13(e184) unc-24(e138) IV. C. elegans Dpy. Unc.
DR194 dpy-11(e224) daf-11(m47) unc-39(e257) V. C. elegans Temperature sensitive dauer constitutive. Leaky. Dpy. Unc.
DR195 dpy-5(e61) daf-16(m26) I. C. elegans Dauer defective. Leaky. Dpy.
DR196 daf-1(m40) dpy-13(e184) IV. C. elegans Temperature sensitive dauer constitutive . Dpy. Maternal effect.
DR2 unc-26(m2) IV. C. elegans Kinky. Coiler.
DR20 daf-12(m20) X. C. elegans Defective dauer formation. Hermaphrodites accumulate oocytes. Males mate poorly.
DR200 daf-2(e1370) III; daf-13(m66) X. C. elegans Temperature sensitive dauer constitutive. Dauers SDS-sensitive.
DR201 dpy-13(e184) daf-14(m77) IV. C. elegans Temperature sensitive dauer constitutive. Dpy. Leaky double at 25C.
DR202 unc-24(e138) daf-14(m77) IV. C. elegans Temperature sensitive dauer constitutive. Unc.
DR205 lon-2(e678) daf-12(m20) X. C. elegans Dauer defective. Long.
DR2054 mIn1 [unc-4(e120) dpy-10(e128)]/let-552(e2542) rol-1(e91) II. C. elegans Heterozygotes are WT and segregate WT, DpyUnc [mIn1(mc6) homozygotes], and two-fold arrest Let Rol progeny. Well balanced. Male stock. Cross WT males to WT hermaphrodites and check for correct segregation of progeny.
DR2055 mIn1(+) II. C. elegans Dark-bodied, unmarked variant of mIn19mC6) with small broods. Presumably balances let-552 to rol-1 (hermaphrodite stock obtained from outcrossing these males to dpy-10 unc-4 was shown to balance this interval). Isolated from DR1982 as a stock that no longer segregated Dpy-10 animals. Not clear whether this strain is the result of chromosome rearrangement in DR1982, or if DR1982 stock was a mixture of mIn1(+)/mIn[dpy-10] and mIn1(+) homozygotes.
DR206 unc-87(e1459) I; eDp23 V. C. elegans Suppressed Unc.
DR2075 mIn1 [unc-4(e120)]/let-552(e2542) rol-1(e91) II. C. elegans Heterozygotes are WT and segregate WT, Lethal Rollers (arrested 2-fold hatchlings), and Unc-4 mIn1(mC6) homozygotes. Pick WT and check for correct segregation of progeny.
DR2078 mIn1 [dpy-10(e128) mIs14]/bli-2(e768) unc-4(e120) II. C. elegans WT gross phenotype, with GFP semi-dominantly expressed in 4-60 cell embyros, pharyngeal muscle and gut. Segregates WT, brighter Dpy GFP mIn1 homozygotes and non-GFP bli-2 unc-4 homozygotes. Pharyngeal and gut GFP is easily seen in a UV dissecting microscope; early embryonic signal requires higher magnification. mIs14 occasionally crosses off mIn1[dpy-10], apparently by double recombination. Pick WT, check for GFP and check for correct segregation of progeny to maintain. mIs14 is ccEx9747 integrated into mIn1[dpy-10]. This is a three-construct element containing myo-2 and pes-10 promoters and a gut enhancer fused individually to GFP coding sequence.
DR210 dpy-5(e61) daf-16(m26) unc-75(e950) I. C. elegans Dauer defective. Dpy. Unc. Leaky.
DR2102 mIn1 [rol-1(e91)]/let-552(e2542) unc-4(e120) II. C. elegans Heterozygotes are WT and segregate WT, Lethal Uncs and Roller mIn1 homozygotes. let-552 unc-4 chromosome is well balanced. Rol does not express until late L4/early adult. Pick WT and check for correct segregation of progeny.
DR211 daf-16(m26) unc-75(e950) I. C. elegans Dauer defective. Unc.
DR215 unc-1(e94) daf-13(m66) X. C. elegans Dauers SDS-sensitive. Unc.
DR2150 mIn1 [rol-1(e91) dpy-10(e128)]/let-552(e2542) unc-4(e120) II. C. elegans Heterozygotes are WT and segregate WT, DpyRol mIn1 homozygotes and 2-fold arrest Unc larvae. Male stock; mate WT males and WT hermaphrodites to maintain.
DR2153 rrf-3(b26) II; liv-4(m872) V. C. elegans Weak Unc (kinker) as adult. Increased life span. Maintain at 15C.
DR2168 liv-2(m882) rrf-3(b26) II. C. elegans Approximately 30% dauer at 27C. Probably thermotolerant because it comes from a thermotolerant selection, but it was not retested. Increaesed longevity. Maintain at 15C.
DR2203 daf-16(m26) I; rrf-3(b26) liv-2(m882) II. C. elegans daf-d. Maintain at 15C.
DR2208 daf-16(m26) I; rrf-3(b26) II; liv-4(m872) V. C. elegans daf-d on starvation. Sterile at 25C. Maintain at 15C. Mild Unc.
DR222 him-1(e879) I; dpy-13(e184) IV. C. elegans Dpy. Segregates males.
DR223 him-1(e879) I; sqt-1(e1350) II. C. elegans Dpy. Segregates males. Semi-dominant Roller.
DR224 daf-1(m40) unc-33(e204) IV. C. elegans Temperature sensitive dauer constitutive. Unc.
DR226 him-1(e879) unc-54(m36) I. C. elegans Unc. Semi-parlayzed. Segregates males. Heterozygotes are slow moving.
DR2278 aap-1(m889) I. C. elegans Dauer formation at 27C. Long-lived. Maternal rescue.
DR2281 daf-9(m540) X. C. elegans Forms dauer larvae non-conditionally but only arrests at dauer stage for 1-2 days, then grows to adult. daf-c but not ts - can grow at 15C or 20C.
DR234 dpy-5(e61) daf-16(m27) I. C. elegans Dauer defective. Dpy.
DR238 dpy-11(e224) mec-9(e1494) V. C. elegans Dpy. Mechanosensory abnormal.
DR240 dpy-11(e224) unc-42(e270) daf-11(m84) V. C. elegans Temperature sensitive dauer constitutive. Dpy. Unc.
DR244 daf-19(m86) sqt-1(e1350) II. C. elegans Temperature sensitive dauer constitutive. Many dauers at 15C. Dpy. Heterozygotes Roll.
DR245 daf-14(m77) unc-22(m52) IV. C. elegans Temperature sensitive dauer constitutive. Dominant Twitcher
DR25 daf-12(m25) X. C. elegans Dauer defective. Class 2 suppressor of dauer constitutives. Chemotaxis normal. See also WBPaper00002149. [Previously called daf-20.]
DR26 daf-16(m26) I. C. elegans Dauer defective-leaky. Somewhat small. Suppresses daf-2.
DR27 daf-16(m27) I. C. elegans Dauer defective. Chemotaxis normal. Class 2 suppressor of dauer constitutive.
DR281 unc-31(e169) dpy-4(e1166) IV. C. elegans Dpy. Unc-slow moving.
DR282 dpy-13(e184) unc-31(e169) IV. C. elegans Dpy. Unc-slow moving.
DR284 unc-32(e189) III; him-8(e1489) IV. C. elegans Unc-coiler. Segregates males. M-MATING-NO SUCCESS.
DR285 sqt-1(e1350) II; him-8(e1489) IV. C. elegans Dpy. Heterozygotes Roll. Segregates males. M-MATING-NO SUCCESS.
DR286 him-8(e1489) IV; unc-58(e665) X. C. elegans Semi-dominant Unc-shaker. Segregates males.
DR288 dpy-13(e184) him-8(e1489) IV. C. elegans Dpy. Segregates males. Semi-dominant.
DR290 unc-54(m36) I; him-8(e1489) IV. C. elegans Severe Unc. Segregates males. M-MATING-NO SUCCESS. Semi-dominant. Heterozygotes are slow moving.
DR291 unc-54(e675) I; eDp23 V. C. elegans Not suppressed. Unc-slow moving.
DR292 che-3(e1379) I; him-8(e1489) IV. C. elegans Dauer defective. Segregates males. Chemotaxis defective (Na+).
DR293 dpy-5(e61) unc-101(m1) I. C. elegans Dpy. Unc-paralyzed coiler.
DR297 unc-15(e1402) I; eDp23 V. C. elegans
DR31 unc-54(m31) I. C. elegans Severe Unc. Very slow growth. Strong semi-dominant. Heterozygous males don't mate.
DR32 unc-54(m32) I. C. elegans Severe Unc. Growth slow. Recessive.
DR33 unc-54(m33) I. C. elegans Movement very slow. Recessive.
DR34 unc-54(m34) I. C. elegans Moves relatively well. Recessive.
DR35 unc-60(m35) V. C. elegans Moves slowly. Recessive. Lays eggs.
DR36 unc-54(m36) I. C. elegans Severe homozygous Unc. Heterozygotes are slow moving. Weakly semi-dominant. Body muscle abnormal.
DR37 unc-54(m37) I. C. elegans Healthy. Recessive. Dauer recovery slow. Eggs laid rarely.
DR373 unc-15(e73) I; sus-1(m156) III; eDp23 V. C. elegans Paralyzed Unc. sus-1 suppresses the ability of eDp23 to suppress unc-15. eDp23 = sup-3(e1407).
DR38 dpy-7(m38) X. C. elegans Temperature sensitive Dpy. Penetrance is incomplete. Left hand roller. Roller low penetrance. Maternal sterile at 25C.
DR39 dpy-3(m39) X. C. elegans Temperature sensitive Dpy. Penetrance is incomplete. Left hand roller. Roller low penetrance. Grows well at 25C.
DR40 daf-1(m40) IV. C. elegans Temperature sensitive dauer constitutive. 100% dauers at 25C. Dauer recovery poor at 15C. Maternal effect. Egg retainer.
DR401 unc-15(e73) I; eDf1 eDp21/dpy-11(e224) V. C. elegans Heterozygotes are slow moving. Hets segregate DpyUncs. Hets segregate larval lethals (eDf1 eDp21 homozygotes).
DR403 eDf1 eDp21/sma-1(e30) V. C. elegans Heterozygotes are WT and segregate WT, Sma and lethals which die in larval development.
DR404 unc-54(e1258) I; eDf1 eDp21/+ V. C. elegans
DR405 unc-54(e190) I; eDf1 eDp21/+ V. C. elegans
DR410 daf-2(m65)/unc-32(e189) III. C. elegans Heterozygotes are WT and segregate WT, dauer constitutive, and Uncs. Lethal dauers.
DR411 dpy-13(e184)/daf-15(m81) IV. C. elegans Heterozygotes are semi-Dpy and segregate semi-Dpy, Dpy and dauers. Dauers are lethal and SDS-sensitive. NOTE: WT recombinants that have lost dpy-13 can quickly overtake a population.
DR412 daf-15(m81)/unc-24(e138) IV. C. elegans Heterozygotes are WT and segregate WT, Unc, and lethal dauers. Dauers are SDS-sensitive.
DR429 dpy-5(e61) unc-15(e73) I. C. elegans Dpy. Unc. Semi-paralyzed.
DR431 daf-19(m86)/mnC1 [dpy-10(e128) unc-52(e444)] II. C. elegans Heterozygotes are WT and segregate WT, dauers and DpyUnc.
DR432 ama-1(m118) IV. C. elegans
DR435 dpy-5(e61) unc-13(e51) I. C. elegans Dpy. Unc.
DR436 dpy-5(e61) unc-14(e57) I. C. elegans Dpy. Unc.
DR437 dpy-5(e61) unc-29(e1072) I. C. elegans Dpy. Unc.
DR438 dpy-5(e61) unc-87(e1216) I. C. elegans DpyUnc strain.
DR439 unc-8(e49) dpy-20(e1282) IV. C. elegans DpyUnc.
DR441 lin-14(n179) X. C. elegans Vulva abnormal. Temperature sensitive. Received new stock from Frank Slack's lab on March 23, 2007.
DR442 unc-8(e49) daf-14(m77) IV. C. elegans Temperature sensitive dauer constitutive. Unc.
DR443 dpy-14(e188) daf-8(e1393) I. C. elegans Temperature sensitive dauer constitutive. Dpy.
DR466 him-5(e1490) V. C. elegans Approx. 33% males.
DR47 daf-11(m47) V. C. elegans Temperature sensitive. Leaky at 25C. Dauers recover poorly at 15C. Dauers escape plates. Recessive. Chemotaxis defective (Na+). Received new stock from Riddle lab in November 2006.
DR476 daf-22(m130) II. C. elegans Dauer defective.
DR49 tln-1(e259) I. C. elegans Unc. Weakly semi-dominant. Scored with difficulty.
DR518 rol-6(su1006) unc-4(e120) II. C. elegans RollerUnc.
DR52 unc-22(m52) IV. C. elegans Unc-Twitcher. Dominant. Genotype questionable.
DR520 sDf9/nT1 IV; +/nT1 V. C. elegans Heterozygotes are WT and segregate WT, Vul, and lethals. Lethal early larval. Heterozygotes twitch in 1% nicotine. Well balanced.
DR54 unc-22(m54) IV. C. elegans Strong Twitcher. Recessive.
DR561 sDf8/nT1 IV; +/nT1 V. C. elegans Heterozygotes are WT and segregate WT, Vul and lethals. Lethal early larval. Heterozygotes twitch in 1% nicotine.
DR6 unc-1(m6) X. C. elegans Kinky Unc.
DR62 daf-7(m62) III. C. elegans Temperature sensitive dauer constitutive. 100% dauers at 25C. Some dauers (3.5%) at 15C.
DR629 unc-15(e73) I; sus-1(m156) daf-2(e1370) III; eDp23 V. C. elegans Temperature sensitive dauers. Paralyzed Unc. sus-1 suppresses the ability of eDp23 to suppress unc-15. eDp23 = sup-3(e1407).
DR63 daf-4(m63) III. C. elegans Temperature sensititve dauer constitutive. Small. 100% dauers at 25C. 15% dauers at 15C.
DR631 unc-54(e190) I; sus-1(m156) III. C. elegans Severly paralyzed Unc. More severe than unc-15 alone.
DR632 unc-15(e73) I; sus-1(m156) III. C. elegans Severly ill and paralyzed. Lays few eggs. More severe than unc-15 alone.
DR66 daf-13(m66) X. C. elegans SDS sensitive dauers. Non-crowder.
DR68 unc-31(m68) IV. C. elegans Slow movement.
DR684 mDf9/nT1 IV; +/nT1 V. C. elegans Heterozygotes are WT and segregate WT, Vul and dead eggs. Homozygous Df is embryonic lethal. Strain is sensitive to alpha-amanitin. New stock received from Patrice Albert 12/95. This strain was generated by the Genetic Toolkit project, which should be acknowledged in any publications resulting from its use: The Genetic Toolkit is funded by the NIH National Center for Research Resources (NCRR) (USA) to Ann M. Rose, David L. Baillie, and Donald L. Riddle. Report all experimental results to Don Riddle.
DR685 dpy-13(e184) ama-1(m118m238)/nT1 IV; +/nT1 V. C. elegans Heterozygotes are WT and segregate WT, Vul, Dpy and dead eggs. Dpys produce progeny at 15C and 20C, but are sterile at 25C. Strain is sensitive to alpha-amanitin.
DR690 unc-17(e113) unc-5(e53)/dpy-13(e184) ama-1(m118) let-272(m243) IV. C. elegans Heterozygotes are semi-Dpy and segregate semi-Dpy, Unc, and DpyLet.
DR691 unc-17(e113) unc-5(e53)/dpy-13(e184) ama-1(m118) let-287(m244) IV. C. elegans Heterozygotes are semi-Dpy and segregate semi-Dpy, Unc and DpyLet. The DpyLets are sterile adults. Maintain by picking semi-Dpy.
DR692 unc-17(e113) unc-5(e53)/dpy-13(e184) ama-1(m118) let-275(m245) IV. C. elegans Heterozygotes are semi-Dpy and segregate semi-Dpy, Unc and DpyLets. Lethal mid-larval. Maintain by picking semi-Dpy.
DR694 unc-17(e113) unc-5(e53)/dpy-13(e184) ama-1(m118) let-281(m247) IV. C. elegans Heterozygotes are semi-Dpy and segregate semi-Dpy, Unc and DpyLet. The DpyLets are adult steriles. Maintain by picking semi-Dpy.
DR695 unc-17(e113) unc-5(e53)/dpy-13(e184) ama-1(m118) let-285(m248) IV. C. elegans Heterozygotes are semi-Dpy and segregate semi-Dpy, Unc and DpyLet. The DpyLet are adult steriles. Maintain by picking semi-Dpy.
DR699 dpy-13(e184) ama-1(m118m252)/nT1 IV; +/nT1 V. C. elegans Heterozygotes are Dpy and segregate Dpy, Vul and dead eggs. Homozygous dpy-13 ama-1 animals are embryonic lethals. Strain is sensitive to alpha-amanitin.
DR7 unc-33(m7) IV; mut-1(e1396). C. elegans Unc.
DR703 unc-17(e113) unc-5(e53)/dpy-13(e184) ama-1(m118) let-274(m256) IV. C. elegans Heterozygotes are semi-Dpy and segregate semi-Dpy, Unc, and DpyLets. Lethal early larval. Maintain by picking semi-Dpy.
DR72 daf-4(m72) III. C. elegans Temperature sensitive dauer constitutive. Small. Amber. Maintain at 15C.
DR721 lin-4(e912) II. C. elegans Completely vulvaless. Long. Uncoordinated. Somewhat clear.
DR722 age-1(m333)/mnC1 [dpy-10(e128) unc-52(e444)] II. C. elegans WT phenotype, segregates WT, Egl (age-1 homozygotes) and DpyUncs. Egl animals give all non-recovering dauer larvae (m333 shows maternal effect), with variable radial shrinkage and variable resistance to 1% SDS. Pick WT to maintain and check for correction segregation of progeny. age-1(m333) pka daf-23(m333).
DR732 daf-15(m81) unc-22(s7)/nT1 IV; +/nT1 V. C. elegans Heterozygotes are WT and segregate WT, Vul, Twitchers which are dauers (dauer constitutive) and dead eggs. Maintain by picking WT. Hets twitch in 1% nicotine.
DR733 lon-2(e678) daf-9(e1406)/unc-78(e1217) X. C. elegans Balanced lethal dauer constitutive. Heterozygotes are WT and segregate WT, LonDaf and Unc. Will get 3-5 adult Lon per clone. Maintain by picking WT.
DR767 unc-17(e113) unc-5(e53)/dpy-13(e184) ama-1(m118) let-288(m306) IV. C. elegans Heterozygotes are semi-Dpy and segregate semi-Dpy, Unc, and DpyLets. DpyLets are adult steriles. Maintain by picking semi-Dpy.
DR77 daf-14(m77) IV. C. elegans Temperature sensitive dauer constitutive. Tight at 25C. Leaky at 15C. Chemotaxis normal.
DR786 ama-1(m322) IV. C. elegans WT strain. Resistant to _-amanitin.
DR787 dpy-13(e184) ama-1(m118) let-276(m240)/nT1 IV; +/nT1 V. C. elegans Heterozygotes are semi-Dpy and segregate semi-Dpy, Vul, DpyLet and dead eggs. Lethal early larval. Maintain by picking semi-Dpy.
DR789 dpy-13(e184) IV/nT1 [let-?(m435)] (IV;V); unc-42(e270) V/nT1 [let-?(m435)] (IV;V). C. elegans Heterozygotes are WT and segregate WT, DpyUnc and dead eggs. Maintain by picking WT.
DR792 sDf2/nT1 IV; +/nT1 V. C. elegans Hets are WT and segregate WT, dead eggs and Vul (nT1/nT1). Clone WT to maintain. Well balanced. The nT1 homozygotes may overtake the plate at 15C or upon starvation.
DR793 dpy-13(e184) mDf7 IV/nT1 [let-?(m435)] (IV;V). C. elegans Heterozygotes are semi-Dpy and segregate semi-Dpy and dead eggs (mDf7/mDf7, nT1/nT1 and aneuploids). This strain was generated by the Genetic Toolkit project, which should be acknowledged in any publications resulting from its use: The Genetic Toolkit is funded by the NIH National Center for Research Resources (NCRR) (USA) to Ann M. Rose, David L. Baillie, and Donald L. Riddle. Report all experimental results to Don Riddle. Rec'd new stock 11/99 from Riddle lab.
DR795 dpy-13(e184) ama-1(m118) let-276(m239)/nT1 IV; +/nT1 V. C. elegans Heterozygotes are semi-Dpy and segregate semi-Dpy, Vul, and dead eggs. Homozygous let-276 are dead eggs. Maintain by picking semi-Dpy.
DR799 mDf4/nT1 IV; +/nT1 V. C. elegans Heterozygotes are semi-Dpy and segregate semi-Dpy, Vul and dead eggs. Maintain by picking semi-Dpy. This strain was generated by the Genetic Toolkit project, which should be acknowledged in any publications resulting from its use: The Genetic Toolkit is funded by the NIH National Center for Research Resources (NCRR) (USA) to Ann M. Rose, David L. Baillie, and Donald L. Riddle. Report all experimental results to Don Riddle.
DR802 mDf5/nT1 IV; +/nT1 V. C. elegans Heterozygotes are semi-Dpy and segregate semi-Dpy, Vul and dead eggs. Maintain by picking semi-Dpy. This strain was generated by the Genetic Toolkit project, which should be acknowledged in any publications resulting from its use: The Genetic Toolkit is funded by the NIH National Center for Research Resources (NCRR) (USA) to Ann M. Rose, David L. Baillie, and Donald L. Riddle. Report all experimental results to Don Riddle.
DR803 mDf6/nT1 IV; +/nT1 V. C. elegans Heterozygotes are semi-Dpy and segregate semi-Dpy, Vul and dead eggs. Maintain by picking semi-Dpy. This strain was generated by the Genetic Toolkit project, which should be acknowledged in any publications resulting from its use: The Genetic Toolkit is funded by the NIH National Center for Research Resources (NCRR) (USA) to Ann M. Rose, David L. Baillie, and Donald L. Riddle. Report all experimental results to Don Riddle. Rec'd new stock 12/99 from Riddle lab.
DR806 dpy-13(e184) ama-1(m118m328)/nT1 IV; +/nT1 V. C. elegans Heterozygotes are WT and segregate WT, Vul, DpyLet and dead eggs. Lethal early larval (L1) at 20C and 25C. Maintain by picking WT.
DR814 dpy-13(e184) ama-1(m118) mDf8 IV/nT1 [let-?(m435)] (IV;V). C. elegans Heterozygotes are semi-Dpy and segregate semi-Dpy, early larval lethals and dead eggs. This strain was generated by the Genetic Toolkit project, which should be acknowledged in any publications resulting from its use: The Genetic Toolkit is funded by the NIH National Center for Research Resources (NCRR) (USA) to Ann M. Rose, David L. Baillie, and Donald L. Riddle. Report all experimental results to Don Riddle.
DR842 mut-4(st700) I; mut-5(st701) II; unc-22(st136m498) IV. C. elegans Non-Twitchers. Still contains Tc1. Temperature sensitive. Sterile at 25C, grows ok at 20C. Dauer larvae are SDS resistant.
DR848 daf-8(e1393) unc-29(e1072) I. C. elegans Unc-weak kinker, doesn't back well. Temperature sensitive dauer constitutive. Maintain at 15C. Makes high percentage of dauers at 25C. tsp for dauer formation is L1 molt. Type C Egl. Active. Resistant to 1 mM levamisole. Sensitive to hypoosmotic shock.
DR86 daf-19(m86) II. C. elegans Temperature sensitive dauer constitutive. Difficult to grow. 100% dauers at 25C. 90% dauers at 15C.
DR907 unc-17(e113) dpy-13(e184) IV; mDp1 (IV;f). C. elegans Animals which carry the Dup are semi-Dpy and segregate semi-Dpy and DpyUnc (animals which have lost the Dup). Animals homozygous for the Dup are slow growing, slender and transparent. This strain was generated by the Genetic Toolkit project, which should be acknowledged in any publications resulting from its use: The Genetic Toolkit is funded by the NIH National Center for Research Resources (NCRR) (USA) to Ann M. Rose, David L. Baillie, and Donald L. Riddle. Report all experimental results to Don Riddle.
DR918 mDf10/nT1 IV; +/nT1 V. C. elegans Heterozygotes are semi-Dpy and segregate semi-Dpy, Vul, early larval lethals and dead eggs. Maintain by picking semi-Dpy. This strain was generated by the Genetic Toolkit project, which should be acknowledged in any publications resulting from its use: The Genetic Toolkit is funded by the NIH National Center for Research Resources (NCRR) (USA) to Ann M. Rose, David L. Baillie, and Donald L. Riddle. Report all experimental results to Don Riddle.
DR921 dpy-7(sc27) daf-9(e1406)/lon-2(e678) X. C. elegans Heterozygotes are WT. At 25C the hets segregate DpyDafs, WT and Lon. At 15C the hets segregate Dafs, WT and Lon. [dpy-7(sc27) is temperature sensitive. At 25C it is larger than most Dpys and has a tendency to roll. Not expressed at 15C.] Maintain by picking WT.
DR927 daf-8(e1393) fer-1(hc1) I. C. elegans Temperature sensitive dauer constitutive. Temperature sensitive fertilization defective. WT at 15C, segregates some dauers at 20C, sterile at 25C. Tightly linked.
DR933 dpy-13(m399) IV. C. elegans Dpy.
DR94 unc-45(m94) III. C. elegans Temperature sensitive Unc. Slow at 15C. Paralyzed at 20C and 25C.
DR942 let-278(m265) dpy-13(e184) ama-1(m118)/nT1 IV; +/nT1 V. C. elegans Heterozygotes are semi-Dpy and segregate semi-Dpy, Vul, DpyLet and dead eggs. The DpyLets are Sterile adults. Maintain by picking semi-Dpy.
DR943 daf-8(e1393) fer-1(hc1) unc-29(e1072) I. C. elegans Unc. Temperature sensitive dauer constitutive. Temperature sensitive fertilization defective (late). UncDaf at 25C, Unc at 15C.
DR96 unc-76(e911) V. C. elegans Coiler Unc. Recessive. Easily scored.
DR97 unc-26(e345) IV. C. elegans Unc.
PD4788 mIs13 I. C. elegans mIs13 [myo-2p::GFP + pes-10p::GFP + gut-promoter::GFP] I. Superficially wild-type. GFP expression in 4-cell embryos, pharyngeal muscle and gut. GFP signal is dim but visible under dissecting scope. See WBG 15 #5 page 20.
PD4790 mIs12 II. C. elegans mIs12 [myo-2p::GFP + pes-10p::GFP + F22B7.9::GFP] II. Hermaphrodites expressing compound GFP reporter (see PD4790). Strong pharyngeal muscle expression, easily scored by GFP dissecting scope. mIs12 is tightly linked to unc-4 II, and not to LG III or IV as previously reported. mIs12 homozygous males mate well (ME3). See WBG 15 #5 page 20. See CB5584.
PD4792 mIs11 IV. C. elegans mIs11 [myo-2p::GFP + pes-10p::GFP + gut-promoter::GFP] IV. GFP expression in 4-cell embryos, pharyngeal muscle and gut. Strong GFP signal. See WBG 15 #5 page 20.
PD4793 mIs10 V. C. elegans mIs10 [myo-2p::GFP + pes-10p::GFP + gut-promoter::GFP] V. WT GFP phenotype, with expression in 4-cell embryos, pharyngeal muscle and gut. Strong GFP signal. Suppresses recombination between unc-60 and dpy-11. See WBG 15 #5 page 20.
PD9753 ccIs9753 I. C. elegans ccIs9753 [myo-2p::GFP + pes-10p::GFP + gut-promoter::GFP]. GFP expression in 4-cell embryos, pharyngeal muscle and gut. Medium-strength GFP signal. See WBG 15 #5 page 20.
temp_name13 unc-13(e51) let-79(s81)/unc-15(e73)I. Deleted from CGC collection 7/92; never frozen.
temp_name27 daf-19(m86) unc-4(e120)II. not behaving-DR86 has things in backgrnd-Mark->dele 4/8/97
temp_name36 daf-18(e1375) dpy-9(e12) IV. Does not contain e1375. May have a different daf mutation.
temp_name5 unc-17(e113) unc-5(e53)/dpy-13(e184) ama-1(m322) let-?(m360)IV. LAB

Alleles contributed by this laboratory

Allele Type DNA Change Protein Change
m435 Allele
m35 Allele
m481 Allele
m1 Allele substitution nonsense
m323 Allele
m118 Allele substitution
m526 Allele substitution
m20 Allele substitution nonsense
m26 Allele substitution splice_site
m583 Allele substitution nonsense
m333 Allele substitution nonsense
m41 Allele substitution
m596 Allele substitution
m579 Allele substitution
m577 Allele substitution
m86 Allele substitution nonsense
m727 Allele
m47 Allele
m52 Allele
m40 Allele substitution nonsense
m2 Allele substitution nonsense
m66 Allele
m77 Allele substitution nonsense
m872 Allele
m882 Allele
m36 Allele
m889 Allele substitution nonsense
m540 Transposon insertion insertion splice_site
m27 Allele substitution nonsense
m362 Allele deletion frameshift
m84 Allele
m25 Allele substitution
m31 Allele
m32 Allele
m33 Allele
m34 Allele
m37 Allele
m156 Allele
m38 Allele substitution
m39 Allele
m65 Allele substitution nonsense
m81 Allele
m116 Allele substitution
m130 Allele substitution
m62 Allele
m72 Allele substitution nonsense
m162 Allele
m54 Allele
m6 Allele
m210 Allele
m212 Allele substitution
m213 Allele substitution
m63 Allele
m221 Allele
m68 Allele substitution nonsense
m235 Allele substitution
m236 Allele substitution
m238 Allele substitution
m243 Allele
m244 Allele
m245 Allele
m247 Allele
m248 Allele
m324 Allele
m252 Allele
m7 Allele
m256 Allele
m258 Allele
m259 Allele
m261 Allele
m262 Allele
m263 Allele
m267 Allele
m269 Allele
m251 Allele substitution
m306 Allele
m332 Allele substitution
m322 Allele substitution
m240 Allele
m239 Allele
m328 Allele
m498 Allele
m367 Allele substitution
m370 Allele substitution
m396 Allele substitution
m399 Allele
m94 Allele substitution
m265 Allele
m402 Transposon insertion insertion
m417 Allele substitution
m419 Allele substitution nonsense
m420 Allele substitution
m421 Allele substitution
m422 Allele substitution nonsense
m424 Allele substitution
m646 Allele substitution nonsense
m158 Allele
m592 Allele substitution
m539 Allele
m160 Allele substitution nonsense
m185 Allele substitution nonsense
m175 Allele substitution nonsense
m201 Allele substitution splice_site
m533 Transposon insertion insertion
m511 Transposon insertion insertion
m537 Allele