Laboratory Information

NameDH View on WormBase
Allele designationb
HeadHirsh, David
InstitutionColumbia University, New York, NY
Address Columbia University 313 Low Library MC 4310 535 West 116th Street New York, NY 10027

Website http://biochemistry.hs.columbia.edu/faculty/hirsh.html
Gene classes act  rme 

Strains contributed by this laboratory

Strain Genotype Species Description
DH1 zyg-1(b1) II. C. elegans Temperature sensitive. Embryonic lethal at 25C (tight); arrests at first cleavage. Gondadogenesis defective. Will grow at 15C or 20C. Maternal effect (m,m).
DH10 mus-101(b10) I. C. elegans Temperature sensitive. Embryonic lethal. Gonadogenesis abnormal. Recessive. Maternal effect (m,m). Strict. Does not grow at 20C or 25C.
DH117 emb-9(b117) III. C. elegans Temperature sensitive. Semi-dominant. Egg lethal. Not maternal. Will grow at 20C.
DH1300 C. briggsae wild isolate. C. briggsae DH subclone of C. briggsae Zuckerman. This stock was maintained in liquid culture for some number of years, and has acquired mutations that have not been named or mapped. It is Unc, dauer-defective and ts lethal. Previously called C. briggsae BO.
DH1390 rme-2(b1008) IV. C. elegans Low brood size and incompletely penetrant embryonic lethality. Accumulates yolk in the pseudocoelom of adult hermaphrodites. Males are normal.
DH18 zyg-3(b18) II. C. elegans Temperature sensitive. Embryonic lethal. Semi-dominant. Gonadogenesis defective. maternal effect (m,n). Will grow at 20C, but not 25C.
DH187 zyg-7(b187) III. C. elegans Temperature sensitive. Egg lethal. Will grow at 20C, but not 25C. Recessive. Maternal effect (m,n).
DH189 emb-9(b189) III. C. elegans Temperature sensitive. Egg lethal. Maternal effect (m,n). Acc and Gon. Some growth at 20C, but not at 25C.
DH2 zyg-11(b2) II. C. elegans Temperature sensitive. Leaky. Penetrance incomplete. Semi-dominant. Cleavage abnormal. Maternal effect(m,m). Received new stock from Edward Kipreos 7/2003.
DH202 tra-2(b202) II. C. elegans Temperature sensitive. XX animals are self-fertile hermaphrodites at 15C. XX animals are sterile males at 25C. ts period begins in late embryo.
DH235 zyg-8(b235) III. C. elegans Temperature sensitive. Egg lethal. Abnormal first cleavage. Maternal effect (m,n).
DH238 sqt-3(b238) V. C. elegans Temperature sensitive roller. PKA rol-4.
DH244 zyg-9(b244) II. C. elegans Temperature sensitive. Egg lethal. Abnormal first cleavage. Strict maternal effect (m,m). Will grow at 20C.
DH26 rrf-3(b26) II. C. elegans Temperature sensitive. Spermatogenesis defective. Rescue by mating with WT male. Sterile at 25C.
DH261 zyg-10(b261) III. C. elegans Temperature sensitive. Egg lethal. Abnormal first cleavage giving small P1 blastomere. Mutant is ts in late L4-early adult. Partial maternal (m,n).
DH404 unc-63(b404) I. C. elegans Unc. Trichlorfon resistant. Lev resistance leaky.
DH424 C. elegans wild isolate. C. elegans Interfertile with N2. Survives freezing lin liquid nitrogen. Temperature sensitive. Brood size like N2. Generation time like N2. Spontaneous males. Reference WBG 10(2) 140-141. Isolated in El Prieto Canyon, CA. Caenorhabditis elegans wild isolate (Tc1 pattern HCC).
DH84 emb-7(b84) III. C. elegans Temperature sensitive. Egg lethal. Gon phenotype if shifted to 25C early. Maternal effect (m,m).
DH89 zyg-5(b89) II. C. elegans Temperature senstive. No growth at 20C or 25C. Weakly semidominant. Egg lethal.
DR1344 C. elegans wild isolate. C. elegans Reference WBG 10(2) 140-141. Previously called Bergerac LY and Bergerac BO. Caenorhabditis elegans wild isolate. DR subclone of Bergerac BO (Tc1 pattern HCA).
DR1345 C. elegans wild isolate. C. elegans Reference WBG 10(2) 104-141 and 11(5) 60. Caenorhabditis elegans wild isolate. DR subclone of Cl2a (Tc1 pattern II).
DR1346 C. elegans wild isolate. C. elegans Reference WBG 10(2) 140-141. Caenorhabditis elegans wild isolate. DR subclone of GA-1 (Tc1 pattern I).
DR1347 C. elegans wild isolate. C. elegans Reference WBG 10(2) 140-141. Caenorhabditis elegans wild isolate. DR subclone of GA-1 (Tc1 pattern I).
DR1348 C. elegans wild isolate. C. elegans Reference WBG 10(2) 140-141. Caenorhabditis elegans wild isolate. DR subclone of GA-1 (Tc1 pattern I).
DR1349 C. elegans wild isolate. C. elegans Reference WBG 10(2) 140-141 and 11(5) 60. Caenorhabditis elegans wild isolate. DR subclone of PA-1.
DR1350 C. elegans wild isolate. C. elegans Reference WBG 10(2) 140-141. Caenorhabditis elegans wild isolate. DR subclone of PA-2 (Tc1 pattern III).
PG-1 Unknown species wild isolate Unknown species Not interfertile with N2. Growth slow. Morphogenesis differs from N2. Collected by M.GALLO. PG-1, -2, -3 appear to be the same species. (Carl Johnson 6/26/93).
PG-2 Unknown species wild isolate Unknown species Not interfertile with N2. Growth slow. Morphogenesis differs from N2. Collected by M.GALLO. PG-1, -2, -3 appear to be the same species. (Carl Johnson 6/26/93).
PG-3 Unknown species wild isolate Unknown species Not interfertile with N2. Growth slow. Morphogenesis differs from N2. Collected by M.GALLO. PG-1, -2, -3 appear to be the same species. (Carl Johnson 6/26/93).
temp_name28 cha-1(b401)IV. replaced with PR1152 per Mike Nonet 5/5/97

Alleles contributed by this laboratory

Allele Type DNA Change Protein Change
b26 Allele
b1 Allele substitution
b10 Allele substitution nonsense
b117 Allele substitution
b1045 Allele deletion
b1023 Allele substitution
b1025 Allele deletion
b126 Allele
b1014 Allele substitution nonsense
b1008 Allele substitution frameshift
b18 Allele
b187 Allele
b189 Allele substitution
b2 Allele
b202 Allele
b235 Allele substitution
b238 Allele
b244 Allele
b245 Allele substitution
b246 Allele substitution
b261 Allele
b404 Allele deletion
b84 Allele
b89 Allele
b232 Allele substitution
b262 Allele
b284 Allele substitution
b309 Allele
b293 Allele
b310 Allele
b299 Allele
b274 Allele substitution nonsense
b298 Allele
b306 Allele
b314 Allele
b281 Allele
b317 Allele
b300 Allele
b285 Allele substitution
b410 Allele
b405 Allele
b53 Allele
b401 Allele
b1013 Allele substitution nonsense
b1001 Allele substitution
b131 Allele substitution