Laboratory Information

NameCE View on WormBase
Allele designationep
HeadExelixis Inc.
InstitutionExelixis Inc., San Francisco, CA
Address 106 Glenhaven Drive Chapel Hill, NC 27516

Gene classes ins  pen 

Strains contributed by this laboratory

Strain Genotype Species Description
CE1047 egl-30(ep271) I. C. elegans Dominant, gain-of-function mutation in egl-30; missense M244I. This strain cannot be distributed to commercial organizations. This strain cannot be used for any commercial purpose or for work on human subjects.
CE1051 goa-1(ep275) I. C. elegans Gln to Stop mutation in residue 205. This strain cannot be distributed to commercial organizations. This strain cannot be used for any commercial purpose or for work on human subjects.
CE1190 unc-74(x19) gla-3(ep312) I. C. elegans Gla. May contain dam-1(op241) in background. This strain cannot be distributed to commercial organizations. This strain cannot be used for any commercial purpose or for work on human subjects.
CE1239 hop-1(ep369) I; sel-12(ep6) spr-3(ep17) X. C. elegans ep369 is a weak allele. ep6 is a deletion allele. This strain cannot be distributed to commercial organizations. This strain cannot be used for any commercial purpose or for work on human subjects.
CE1255 cep-1(ep347) I. C. elegans Resistant to radiation-induced apoptosis (Dam); non-Gla; very weak Rad; no gross phenotype. This strain cannot be distributed to commercial organizations. This strain cannot be used for any commercial purpose or for work on human subjects.
CE1258 eat-16(ep273) I. C. elegans Missense mutation E158K. Worms are Egl-c, Eat, and loopy-Unc. This strain cannot be distributed to commercial organizations. This strain cannot be used for any commercial purpose or for work on human subjects.
CE1338 epIs14. C. elegans epIs14 [sbp-1p::GFP + rol-6(su1006)]. Rollers. sbp-1 previously known as pin-1. This strain cannot be distributed to commercial organizations. This strain cannot be used for any commercial purpose or for work on human subjects.
CE1463 vps-41(ep402) unc-6(e78)/dpy-8(e130) unc-6(e78) X. C. elegans Heterozygotes are Unc. Segregtes DpyUncs. Segregates Uncs which are recessive Mel. This strain cannot be distributed to commercial organizations. This strain cannot be used for any commercial purpose or for work on human subjects.
CE1494 +/hT2 [dpy-18(h662)] I; pen-2(ep220)/hT2 [bli-4(e937)] III. C. elegans Heterozgyotes are WT and segregate WT, Dpys, and Ste or Mel. Pick wild-type individuals and check for correct segregation of progeny to maintain. bli-4 is suppressed by dpy-1 in hT2 homozygotes-only see a very few DpyBli.This strain cannot be distributed to commercial organizations. ep220 is likely Mel. This strain cannot be distributed to commercial organizations. This strain cannot be used for any commercial purpose or for work on human subjects.
CE1570 vps-35(ep442) rol-1(e91) II. C. elegans Weak Egl. Rollers. This strain cannot be distributed to commercial organizations. This strain cannot be used for any commercial purpose or for work on human subjects.
CE1857 ect-2(e1778)/unc-4(e120) sqt-1(sc13) II. C. elegans Heterozygotes are WT and segregate WT, Roller Uncs, and ect-2 homozygotes (sterile Uncs which reach adulthood, sometimes giving polynucleate oocytes). ect-2 pka let-21. This strain cannot be distributed to commercial organizations. This strain cannot be used for any commercial purpose or for work on human subjects.
CE548 sbp-1(ep79) III; epEx141. C. elegans epEx141 [sbp-1::GFP::SBP-1 + rol-6(su1006)]. ep79 is a strong allele of sbp-1 (ts lethal). sbp-1 aka pin-1. This strain cannot be distributed to commercial organizations. This strain cannot be used for any commercial purpose or for work on human subjects.
CE778 unc-29(e1072) aph-1(ep140)/fog-3(q443) I. C. elegans This strain cannot be distributed to commercial organizations. This strain cannot be used for any commercial purpose or for work on human subjects.
CE833 sbp-1(ep176) III. C. elegans Weak sbp-1 allele. sbp-1 aka pin-1. This strain cannot be distributed to commercial organizations. This strain cannot be used for any commercial purpose or for work on human subjects. NOTE: This strain carries an unknown GFP marker.
JJ1068 hmp-2(zu364)/hIn1 [unc-54(h1040)] I. C. elegans hmp-2(zu364) homozygotes are 99% embryonic or L1 lethal due to a defect in embryonic body elongation; approximately 1% survive to adult stages. Well balanced by hIn1. Maintain by picking WT.

Alleles contributed by this laboratory

Allele Type DNA Change Protein Change
ep271 Allele substitution
ep275 Allele substitution nonsense
ep312 Allele deletion
ep369 Allele
ep6 Allele
ep17 Allele
ep347 Allele deletion
ep273 Allele substitution
ep402 Allele substitution nonsense
ep220 Allele substitution nonsense
ep442 Allele deletion
ep79 Allele deletion
ep140 Allele substitution nonsense
ep176 Allele