Laboratory Information
| Name | BZ View on WormBase |
|---|---|
| Allele designation | eg |
| Head | McIntire, Steve |
| Institution | Gallo Center, UCSF, San Francisco, CA |
| Address | Programs in Biological Sciences and Biomedical Sciences
Department of Neurology
Gallo Center, UCSF
5858 Horton St., Suite 200
Emeryville, CA 94608 |
| Website | http://www.galloresearch.org/index.php/investigators/mcintirelab |
| Gene classes | chb islo seb sgca swa |
Strains contributed by this laboratory
| Strain | Genotype | Species | Description |
|---|---|---|---|
| BZ555 | egIs1 IV. | C. elegans | egIs1 [dat-1p::GFP]; reportedly maps to LG IV. Bright GFP observable in dopamine neuronal soma and processes. For some reason this strain is resistant to neurotoxic effects of 6-OHDA compared to an independent strain BY200 (Nass et al., 2002). Or maybe BY200 is more sensitive to 6-OHDA due to its co-injection marker gene rol-6? |
| BZ873 | aaim-1(ok295) X. | C. elegans | Dopamine receptor knockout. [NOTE: (3/3/2025) ok295 was previously described as an allele of dop-3/T14E8.4, but is actually an allele of aaim-1/T14E8.4.1 according to current gene models.] Derived by out-crossing parental strain RB563. Outer Left Sequence: ttgctccagcggttctagtt. Outer Right Sequence: gactgtctaagcgaccagcc. Inner Left Sequence: ttgtttgcgggtttgataca. Inner Right Sequence: agaagcacgcggtagttgat. Inner Primer PCR Length: 3254. Estimated Deletion Size: about 1000 bp. |
Alleles contributed by this laboratory
| Allele | Type | DNA Change | Protein Change |
|---|---|---|---|
| eg142 | Allele | substitution | nonsense |
| eg28 | Allele | substitution | nonsense |
| eg978 | Allele | substitution |