Laboratory Information

NameAR View on WormBase
Allele designationmr
HeadRoth, Mark
InstitutionFred Hutchinson Cancer Research Center, Seattle, WA
Address Fred Hutchinson Cancer Research Center
1100 Fairview Avenue North
Seattle 98109
United States
Website http://www.fhcrc.org/science/basic/labs/roth/
Gene classes cbs  cysl  ethe  hcp  san  sqr  sqrd  suls 

Strains contributed by this laboratory

Strain Genotype Species Description
AR1 hcp-6(mr17) I. C. elegans 15C: no phenotype. 26C: shifted as L4 or later results in 100% embryonic lethality; shifted before L4 results in Unc and Sterile animals. Intermediate phenotypes between 20-23C.
AR10 cysl-1(mr25) X. C. elegans Sensitive to hydrogen sulfide and hydrogen cyanide. Reference: Budde MW, Roth MB. Genetics. 2011 Oct;189(2):521-32.
AR11 cysl-1(mr26) X. C. elegans Sensitive to hydrogen sulfide and hydrogen cyanide. Reference: Budde MW, Roth MB. Genetics. 2011 Oct;189(2):521-32.
AR12 suls-1(mr27) V. C. elegans Sensitive to hydrogen sulfide. Reference: Budde MW, Roth MB. Genetics. 2011 Oct;189(2):521-32.
AR13 sqrd-1(mr28) IV. C. elegans Sensitive to hydrogen sulfide. Reference: Budde MW, Roth MB. Genetics. 2011 Oct;189(2):521-32.
AR14 cysl-1(mr29) X. C. elegans Sensitive to hydrogen sulfide and hydrogen cyanide. Reference: Budde MW, Roth MB. Genetics. 2011 Oct;189(2):521-32.
AR15 sqrd-1(mr30) IV. C. elegans Sensitive to hydrogen sulfide. Reference: Budde MW, Roth MB. Genetics. 2011 Oct;189(2):521-32.
AR16 suls-2(mr31) I. C. elegans Sensitive to hydrogen sulfide. Reference: Budde MW, Roth MB. Genetics. 2011 Oct;189(2):521-32.
AR17 sqrd-1(mr32) IV. C. elegans Sensitive to hydrogen sulfide. Reference: Budde MW, Roth MB. Genetics. 2011 Oct;189(2):521-32.
AR18 cysl-1(mr33) X. C. elegans Sensitive to hydrogen sulfide and hydrogen cyanide. Reference: Budde MW, Roth MB. Genetics. 2011 Oct;189(2):521-32.
AR19 cysl-1(mr34) X. C. elegans Sensitive to hydrogen sulfide and hydrogen cyanide. Reference: Budde MW, Roth MB. Genetics. 2011 Oct;189(2):521-32.
AR2 hcp-6(mr17) unc-73(e936) I. C. elegans Unc at all temperatures. For hcp-6: 15C: no phenotype. 26C: shifted as L4 or later results in 100% embryonic lethality; shifted before L4 results in Unc and Sterile animals. Intermediate phenotypes between 20-23C.
AR20 suls-1(mr35) V. C. elegans Sensitive to hydrogen sulfide. Reference: Budde MW, Roth MB. Genetics. 2011 Oct;189(2):521-32.
AR21 suls-2(mr36) I. C. elegans Sensitive to hydrogen sulfide. Reference: Budde MW, Roth MB. Genetics. 2011 Oct;189(2):521-32.
AR22 (mr37) ?. C. elegans Sensitive to hydrogen sulfide. Reference: Budde MW, Roth MB. Genetics. 2011 Oct;189(2):521-32.
AR23 suls-1(mr38) V. C. elegans Sensitive to hydrogen sulfide. Reference: Budde MW, Roth MB. Genetics. 2011 Oct;189(2):521-32.
AR24 cysl-1(mr39) X. C. elegans Sensitive to hydrogen sulfide and hydrogen cyanide. Reference: Budde MW, Roth MB. Genetics. 2011 Oct;189(2):521-32.
AR25 cysl-1(mr40) X. C. elegans Sensitive to hydrogen sulfide and hydrogen cyanide. Reference: Budde MW, Roth MB. Genetics. 2011 Oct;189(2):521-32.
AR3 suls-1(mr18) V. C. elegans Sensitive to hydrogen sulfide. Reference: Budde MW, Roth MB. Genetics. 2011 Oct;189(2):521-32.
AR4 cysl-1(mr19) X. C. elegans Sensitive to hydrogen sulfide and hydrogen cyanide. Reference: Budde MW, Roth MB. Genetics. 2011 Oct;189(2):521-32.
AR5 hif-1(mr20) V. C. elegans Sensitive to hydrogen sulfide and hydrogen cyanide. Reference: Budde MW, Roth MB. Genetics. 2011 Oct;189(2):521-32.
AR6 sqrd-1(mr21) IV. C. elegans Sensitive to hydrogen sulfide. Reference: Budde MW, Roth MB. Genetics. 2011 Oct;189(2):521-32.
AR7 hif-1(mr22) V. C. elegans Sensitive to hydrogen sulfide and hydrogen cyanide. Reference: Budde MW, Roth MB. Genetics. 2011 Oct;189(2):521-32.
AR8 cysl-1(mr23) X. C. elegans Sensitive to hydrogen sulfide and hydrogen cyanide. Reference: Budde MW, Roth MB. Genetics. 2011 Oct;189(2):521-32.
AR9 sqrd-1(mr24) IV. C. elegans Sensitive to hydrogen sulfide. Reference: Budde MW, Roth MB. Genetics. 2011 Oct;189(2):521-32.

Alleles contributed by this laboratory

Allele Type DNA Change Protein Change
mr17 Allele substitution
mr25 Allele substitution splice_site
mr26 Allele substitution
mr27 Allele
mr28 Allele substitution
mr29 Allele substitution
mr30 Allele
mr31 Allele
mr32 Allele substitution
mr33 Allele substitution
mr34 Allele
mr35 Allele
mr36 Allele
mr38 Allele
mr39 Allele substitution
mr40 Allele
mr18 Allele
mr19 Allele substitution splice_site
mr20 Allele
mr21 Allele substitution splice_site
mr22 Allele
mr23 Allele substitution
mr24 Allele substitution