Laboratory Information
| Name | AM View on WormBase |
|---|---|
| Allele designation | rm |
| Head | Richard I. Morimoto |
| Institution | Northwestern University, Evanston, IL |
| Address | Morimoto Laboratory Northwestern University 2205 Tech Drive, Hogan 2-100 Evanston 60208 United States |
| Website | http://www.biochem.northwestern.edu/morimoto/index.html |
| Gene classes | bag chn osr phi tspr ttc |
Strains contributed by this laboratory
| Strain | Genotype | Species | Description |
|---|---|---|---|
| AM1 | osr-1(rm1) I. | C. elegans | Osmotic stress resistant. Received new stock May 7, 2008. |
| AM101 | rmIs110. | C. elegans | rmIs110 [F25B3.3p::Q40::YFP]. Pan-neuronal YFP expression. Reference: Gidalevitz T, et al., Science. 2006 Mar 10;311(5766):1471-4. |
| AM1246 | rmIs126 X. | C. elegans | rmIs126 [unc-54p::Q0::YFP]. Diffuse distribution of Q0::YFP throughout the body-wall muscle cells. Worms maintain a soluble phenotype for the duration of their lifespan. [NOTE: This strain is a replacement for AM134, which was removed from distribution due to reports that it did not carry the correct transgene.] |
| AM138 | rmIs130 II. | C. elegans | rmIs130 [unc-54p::Q24::YFP]. Diffuse distribution of Q24::YFP throughout the body-wall muscle cells. |
| AM140 | rmIs132 I. | C. elegans | rmIs132 [unc-54p::Q35::YFP]. AM140 animals show a Q35::YFP progressive transition from soluble to aggregated as they age. |
| AM141 | rmIs133. | C. elegans | rmIs133 [unc-54p::Q40::YFP]. AM141 animals show a soluble Q40::YFP distribution in body wall muscle cells immediately after hatching. As these worms age the rapid formation of foci is observed. When they reach adulthood, AM141 animals show an entirely Q40::YFP aggregated phenotype. |
| AM263 | rmIs175. | C. elegans | rmIs175 [unc-54p::Hsa-sod-1 (WT)::YFP]. Array encodes wild-type human SOD-1. YFP expression in body wall muscle. Array is prone to silencing; maintain by picking worms displaying typical aggregation patterns. Reference: Gidalevitz T, et al., PLoS Genet. 2009 Mar;5(3):e1000399. |
| AM44 | rmIs190. | C. elegans | rmIs190 [F25B3.3p::Q67::CFP]. Pan-neuronal CFP expression. |
| AM49 | rmIs172. | C. elegans | rmIs172 [F25B3.3p::Q19::CFP]. Pan-neuronal CFP expression. Reference: Gidalevitz T, et al., Science. 2006 Mar 10;311(5766):1471-4. |
| AM725 | rmIs290. | C. elegans | rmIs290 [unc-54p::Hsa-sod-1 (127X)::YFP]. Array encodes mutated form of human SOD-1. YFP expression in body wall muscle. Array is prone to silencing; maintain by picking worms displaying typical aggregation patterns. Reference: Gidalevitz T, et al., PLoS Genet. 2009 Mar;5(3):e1000399. |
Alleles contributed by this laboratory
| Allele | Type | DNA Change | Protein Change |
|---|---|---|---|
| rm1 | Allele | substitution | splice_site |