Laboratory Information
| Name | AH View on WormBase |
|---|---|
| Allele designation | zh |
| Head | Hajnal, Alex |
| Institution | University of Zurich, Zurich, Switzerland |
| Address | Institute of Molecular Life Sciences IMLS Y55L88 Michael Daube Winterthurerstrasse 190 Zurich 8057 Switzerland |
| Website | http://www.imls.uzh.ch/research/Hajnal.html |
| Gene classes | agr dep herc lip rom trim |
Strains contributed by this laboratory
| Strain | Genotype | Species | Description |
|---|---|---|---|
| AH102 | lip-1(zh15) IV. | C. elegans | Deletion allele which removes exons 2 to 6 of lip-1 (C05B10.1). Incompletely penetrant ovulation defect. |
| AH12 | gap-1(ga133) X. | C. elegans | Null allele. |
| AH142 | zhIs4 III. | C. elegans | zhIs4 [lip-1::GFP] III. lip-1::GFP transcriptional reporter expression is upregulated in the secondary VPCs P5.p and P7.p of early L3 animals. |
| AH159 | sra-13(zh13) II. | C. elegans | sra-13(zh13) mutants display stronger chemotaxis to limiting concentrations of isoamylalcohol and diacetyl than WT animals. Deletion allele. 396 bp of 5' promoter sequence and all but the last exon are removed; probably a null allele. |
| AH1747 | unc-119(ed3) III; zhIs35 I. | C. elegans | zhIs35 [let-23::GFP + unc-119(+)] I. zhIs35 resuces let-23(sy1) and recapitulates LET-23 antibody staining in VPCs. let-23::GFP transgene expression is higher in this strain than in AH1779 unc-119(ed3) III; zhIs38. Reference: Haag A, et al. PLoS Genet. 2014 May 1;10(5):e1004341. |
| AH1779 | unc-119(ed3) III; zhIs38 IV. | C. elegans | zhIs38 [let-23::GFP + unc-119(+)] IV. zhIs38 resuces let-23(sy1) and recapitulates LET-23 antibody staining in VPCs. let-23::GFP transgene is expressed at levels similar to endogenous LET-23. Reference: Haag A, et al. PLoS Genet. 2014 May 1;10(5):e1004341. |
| AH205 | sdn-1(zh20) X. | C. elegans | Slightly Unc. Variably Egl. zh20 is a deletion in sdn-1. The sequence of the breakpoint is: TTTGCTTCACAC//zh20//GTCGACAGGCAG. |
| AH286 | unc-4(e120) ect-2(zh8) II; gap-1(ga133) X. | C. elegans | Muv and Unc. Semi-dominant mutation in ect-2 (previously called let-21). |
| AH3437 | tln-1(zh117[gfp::tln-1]) I. | C. elegans | Wild-type morphology. Endogenous GFP reporter for tln-1. Reference: Walser M, et al. PLoS Genet. 2017 Jan 30;13(1):e1006592. |
| AH346 | dep-1(zh34) unc-4(e120) II; lip-1(zh15) IV. | C. elegans | Pvl and weak Muv. Transformation of secondary to primary vulval cell fates. |
| AH75 | apr-1(zh10) unc-29(e1072) I; zhEx11. | C. elegans | zhEx11[apr-1(+) + sur-5::GFP]. Unc. Segregates dead eggs that have lost the rescuing array. |
Alleles contributed by this laboratory
| Allele | Type | DNA Change | Protein Change |
|---|---|---|---|
| zh15 | Allele | deletion | |
| zh13 | Allele | deletion | |
| zh20 | Allele | deletion | |
| zh8 | Allele | ||
| zh34 | Allele | substitution | nonsense |
| zh10 | Allele | ||
| zh17 | Allele | substitution | nonsense |