Laboratory Information

NameAH View on WormBase
Allele designationzh
HeadHajnal, Alex
InstitutionUniversity of Zurich, Zurich, Switzerland
Address Institute of Molecular Life Sciences
IMLS Y55L88 Michael Daube
Winterthurerstrasse 190
Zurich 8057
Switzerland
Website http://www.imls.uzh.ch/research/Hajnal.html
Gene classes agr  dep  herc  lip  rom  trim 

Strains contributed by this laboratory

Strain Genotype Species Description
AH102 lip-1(zh15) IV. C. elegans Deletion allele which removes exons 2 to 6 of lip-1 (C05B10.1). Incompletely penetrant ovulation defect.
AH12 gap-1(ga133) X. C. elegans Null allele.
AH142 zhIs4 III. C. elegans zhIs4 [lip-1::GFP] III. lip-1::GFP transcriptional reporter expression is upregulated in the secondary VPCs P5.p and P7.p of early L3 animals.
AH159 sra-13(zh13) II. C. elegans sra-13(zh13) mutants display stronger chemotaxis to limiting concentrations of isoamylalcohol and diacetyl than WT animals. Deletion allele. 396 bp of 5' promoter sequence and all but the last exon are removed; probably a null allele.
AH1747 unc-119(ed3) III; zhIs35 I. C. elegans zhIs35 [let-23::GFP + unc-119(+)] I. zhIs35 resuces let-23(sy1) and recapitulates LET-23 antibody staining in VPCs. let-23::GFP transgene expression is higher in this strain than in AH1779 unc-119(ed3) III; zhIs38. Reference: Haag A, et al. PLoS Genet. 2014 May 1;10(5):e1004341.
AH1779 unc-119(ed3) III; zhIs38 IV. C. elegans zhIs38 [let-23::GFP + unc-119(+)] IV. zhIs38 resuces let-23(sy1) and recapitulates LET-23 antibody staining in VPCs. let-23::GFP transgene is expressed at levels similar to endogenous LET-23. Reference: Haag A, et al. PLoS Genet. 2014 May 1;10(5):e1004341.
AH205 sdn-1(zh20) X. C. elegans Slightly Unc. Variably Egl. zh20 is a deletion in sdn-1. The sequence of the breakpoint is: TTTGCTTCACAC//zh20//GTCGACAGGCAG.
AH286 unc-4(e120) ect-2(zh8) II; gap-1(ga133) X. C. elegans Muv and Unc. Semi-dominant mutation in ect-2 (previously called let-21).
AH3437 tln-1(zh117[gfp::tln-1]) I. C. elegans Wild-type morphology. Endogenous GFP reporter for tln-1. Reference: Walser M, et al. PLoS Genet. 2017 Jan 30;13(1):e1006592.
AH346 dep-1(zh34) unc-4(e120) II; lip-1(zh15) IV. C. elegans Pvl and weak Muv. Transformation of secondary to primary vulval cell fates.
AH4617 pat-3(zh115[pat-3::gfp]) III C. elegans wild-type morphology. Endogenous gfp reporter for pat-3
AH75 apr-1(zh10) unc-29(e1072) I; zhEx11. C. elegans zhEx11[apr-1(+) + sur-5::GFP]. Unc. Segregates dead eggs that have lost the rescuing array.

Alleles contributed by this laboratory

Allele Type DNA Change Protein Change
zh15 Allele deletion
zh13 Allele deletion
zh20 Allele deletion
zh8 Allele
zh34 Allele substitution nonsense
zh10 Allele
zh17 Allele substitution nonsense