Laboratory Information

NameAE View on WormBase
Allele designationat
HeadSluder, Ann
InstitutionMassachusetts General Hospital, Charlestown, MA
Address Director of Biology, Animal Health Scynexis, Inc. PO Box 12878 Research Triangle Park, NC 27709-2878

Gene classes cnr  crf  dml  nhr 

Strains contributed by this laboratory

Strain Genotype Species Description
AA107 nhr-48(ok178) X. C. elegans ZK662.3 Homozygous. No obvious phenotype. Outer left primer sequence: TCTGAAGTTTGTGAGCCGTG. Outer right primer sequence: AGCGCCTAGATGAGCAACAT. Inner left primer sequence: TCCGTTGAATGCCATCTGTA. Inner right primer sequence: GGACGATGCACATGAGTTTG. Inner primer PCR product length: 3324 bp. Deletion size: 1956 bp.
AE501 nhr-8(ok186) IV. C. elegans Approx. 1.3 kb deletion - does not remove entire coding region, might not be null allele. No overt morphological or behavioral abnormalities. Homozygotes are 2-3X more sensitive to colchicine and chloroquine than are N2 animals.
This laboratory hasn't submitted any alleles to the CGC.