Variation Information: gt1981
Name | gt1981 View on WormBase |
---|---|
Species | C. elegans |
Genetic position | X:-6.80 +/- 0.000 cM |
Genomic position | X: 4712894..4712894 |
Protein change | F55D10.3 Substitution |
Strains carrying this variation
Strain | Genotype | Species | Description |
---|---|---|---|
TG4100 | vtIs1 V; glit-1(gt1981) X. | C. elegans | vtIs1 [dat-1p::GFP + rol-6(su1006)] V. Strain does not roll obviously. gt1981 is a point mutation in a highly conserved residue. Hypersensitive to oxidative stress: Increased dopaminergic neurodegeneration after 6-OHDA exposure and increased developmental delay after exposure to rotenone and paraquat. Reference: Offenburger SL, et al. https://www.biorxiv.org/content/early/2017/10/13/203067. |