Variation Information: tm423

Nametm423 View on WormBase
Species C. elegans
Genetic positionIV:3.20 +/- 0.000 cM
Genomic positionIV: 6550140..6550550
Protein changeC01G5.8a C01G5.8b Deletion

Strains carrying this variation

Strain Genotype Species Description
CV199 fan-1(tm423) IV/nT1 [qIs51] (IV;V). C. elegans Maintain under normal condition. Heterozygotes are WT with pharyngeal GFP signal, and segregate WT GFP, arrested nT1[qIs51] aneuploids, and non-GFP fan-1 homozygotes. Homozygous nT1[qIs51] inviable. Pick WT GFP and check for correct segregation of progeny to maintain. Reference: Smogorzewska A, et al. (2010) Molec Cell 39:36-47.
TG1568 fan-1(tm423) IV. C. elegans 411 bp deletion removes exons 6-8. Homozygotes are viable, but are hypersensitive to DNA crosslinking.
WS5229 unc-119(ed3) III; fan-1(tm423) IV; opIs406. C. elegans opIs406 [fan-1p::fan-1::GFP::let-858 3'UTR + unc-119(+)]. opIs406 resuces tm423. Reference: Kratz K, et al. Cell. 2010 Jul 9;142(1):77-88.