Variation Information: tm373

Nametm373 View on WormBase
Species C. elegans
Genetic positionIV:8.48 +/- 0.003 cM
Genomic positionIV: 13211936..13213630
Protein changeC48D1.3 Deletion

Strains carrying this variation

Strain Genotype Species Description
RM1743 cha-1(md39) cho-1(tm373) IV. C. elegans Temperature-sensitive lethal. Maintain at 15C. At 16-20C: aldicarb-resistant, small, Unc-coily, slow-growing, slow pharyngeal pumping. At 25C: tight coils, virtually no movement, virtually no pumping, no growth, lethal. References: Rand JB. Genetics. 1989 May;122(1):73-80. Mullen GP, et al. Genetics. 2007 Sep;177(1):195-204.
RM2576 cho-1(tm373) IV. C. elegans Canonical allele. Superficially wild-type. Frequency of spontaneous reversals approximately twice that of wild type. Initial L4 swimming rate approximately half that of wild type, and decreases steadily for 30 min, until the animals are immobile. Synthetic lethal with pmt-2 RNAi.
RM3156 oct-1(gk354) I; cho-1(tm373) IV. C. elegans Slightly Lon and Unc. Reference: Mullen GP, et al. Genetics. 2007 Sep;177(1):195-204.
RM3157 cho-1(tm373) IV; chtl-1(ok1695) X. C. elegans Slightly Lon and Unc. Reference: Mullen GP, et al. Genetics. 2007 Sep;177(1):195-204.
RM3218 pha-1(e2123) III; cho-1(tm373) IV; mdEx790. C. elegans mdEx790 [cho-1p(7.6kb)::cho-1::GFP + pha-1(+) + pBluescript]. CHO-1 translational fusion driven by 7.6 kb cho-1 promoter rescues cho-1 mutant behaviors, including reduced initial thrashing rate, fatigue, and synthetic interactions with pmt-2. Strong fluorescence in nerve ring, and ventral and dorsal nerve cords. Structure of the transgene is shown in Figure 1 of Mullen et al., 2007.
RM3248 oct-1(gk354) I; cho-1(tm373) IV; chtl-1(ok1695) X. C. elegans Approximately wild-type in appearance, growth, and movement. Reference: Mullen GP, et al. Genetics. 2007 Sep;177(1):195-204.