Variation Information: gk370

Namegk370 View on WormBase
Species C. elegans
Genetic positionI:2.11 +/- 0.007 cM
Genomic positionI: 7540688..7541441
Protein changeC26C6.5a C26C6.5b Deletion

Strains carrying this variation

Strain Genotype Species Description
VC924 dcp-66(gk370) I/hT2 [bli-4(e937) let-?(q782) qIs48] (I;III). C. elegans C26C6.5a. Homozygous sterile deletion chromosome balanced by bli-4-, let-?- and GFP-marked translocation. Heterozygotes are WT with pharyngeal GFP signal, and segregate WT GFP, arrested hT2 aneuploids, and non-GFP gk370 homozygotes (scrawny, Unc sterile, often with protruding vulva; distintegrates in early adulthood). Homozygous hT2[qIs48] inviable. Note: qIs48 has been observed to recombine off hT2, typically leaving behind a functional homozygous viable hT2 with Bli-4 phenotype. Pick WT GFP and check for correct segregation of progeny to maintain. Attribution: This strain was provided by the C. elegans Reverse Genetics Core Facility at the University of British Columbia, which is part of the international C. elegans Gene Knockout Consortium, which should be acknowledged in any publications resulting from its use. Paper_evidence WBPaper00041807