Variation Information: tm1842

Nametm1842 View on WormBase
Species C. elegans
Genetic positionIII:21.21 +/- 0.000 cM
Genomic positionIII: 13423988..13424546
Protein changeF45G2.3 Deletion

Strains carrying this variation

Strain Genotype Species Description
NB131 wrn-1(gk99)/mIn1[dpy-10(e128) mIs14(GFP)] II; exo-1(tm1842) III. C. elegans Heterozygotes (wrn-1/mIn1;exo-1) are WT and GFP+. mIn1 homozygotes (mIn1;exo-1) are Dpy and GFP+. wrn-1;exo-1 homozygotes are non-GFP.  Reference: Ryu, J.S. and Koo, H.S. (2017). FEBS Lett.
NB514 exo-1(tm1842) III; parg-2(ok980) IV. C. elegans Double mutant is less sensitive to ionizing radiation than the parg-2(ok980) single mutant, but as sensitive as the exo-1(tm1842) single mutant. Parental parg-2(ok980) strain outcrossed 6 times; parental exo-1(tm1842) strain outcrossed 4 times. Reference: Bae W, et al. Hypersensitivity to DNA double-strand breaks associated with PARG deficiency is suppressed by exo-1 and polq-1 mutations in Caenorhabditis elegans. The FEBS Journal, In press.
SSM72 exo-1(tm1842) III. C. elegans Reference: Yin Y & Smolikove S. Mol Cell Biol. 2013 Jul;33(14):2732-47.