Variation Information: u218

Nameu218 View on WormBase
Species C. elegans
Genetic positionI:3.76 +/- 0.000 cM
Genomic positionI: 9442079..9442079
Protein changeF46A9.6 F46A9.6 Substitution

Strains carrying this variation

Strain Genotype Species Description
SP1560 mec-8(u218) I. C. elegans Temperature sensitive mec-8 allele.
SP1564 mec-8(u218) smu-1(mn609) I; unc-52(e669su250ts) II. C. elegans Temperature sensitive mec-8 allele, mechanosensory abnormal at 25 C. Reference: Spike CA, et al. Mol Cell Biol. 2001 Aug;21(15):4985-95.
SP2123 mec-8(u218) smu-1(mn602) I; unc-52(e669su250ts) II. C. elegans Temperature sensitive mec-8 allele, mechanosensory abnormal at 25 C. Reference: Spike CA, et al. Mol Cell Biol. 2001 Aug;21(15):4985-95.
TU218 mec-8(u218) I. C. elegans Temperature sensitive. Mechanosensory abnormal at 25 C. Maintain at 15 C. Reference: Chalfie & Sulston (1981) Dev Biol 82:358.
TU3135 mec-8(u218) I; rde-1(ne219) V; uIs46. C. elegans uIs46 [rde-1p::mec-2(intron9)::rde-1) + ceh-22::GFP]. Temperature sensitive; maintain at 15 C. RNAi-sensitive at 15 C. Mechanosensory abnormal at 25 C. Uses the ninth intron of mec-2, whose splicing depends on mec-8, to produce temperature-sensitive expression and temperature-sensitive RNAi. Reference: Calixto et al. (2010) Nature Methods 7:407-11.