Variation Information: md290

Namemd290 View on WormBase
Species C. elegans
Genetic positionII:0.12 +/- 0.000 cM
Genomic positionII: 6812965..6816228
Protein changeF31E8.2a F31E8.2b Deletion

Strains carrying this variation

Strain Genotype Species Description
MT8191 snt-1(md290) unc-104(e1265) II/mnC1 [dpy-10(e128) unc-52(e444)] II. C. elegans Heterozygotes are WT and segregate WT, Unc, and paralyzed Dpy Uncs. Reference: Jorgensen EM, Nature. 1995 Nov 9;378(6553):196-9.
NM204 snt-1(md290) II. C. elegans snt-1 encodes the C. elegans homolog of synaptotagmin I. md290 is a deletion that removes most of the coding sequence. Strain is a slow growing aldicarb resistant (Ric) Unc. Males won't mate.
RM1613 snt-1(md290) II. C. elegans snt-1(md290) is a 3264-bp deletion removing all coding sequence in exons 3-8. Breakpoints: ttatagatttcaattaaatagtaaacaaaa / / aatctctctttgttttcactcttccaacat. Reference: Nonet ML, et al. Cell. 1993 Jul 2;73(7):1291-305.
RM3054 snt-1(md290) II; mdIs126; mdIs129. C. elegans mdIs126 [snt-1p::snt-1(genomic; B-stop)::CFP]. mdIs129 [snt-1p::snt-1(genomic; A-stop)::YFP]. snt-1 mutation in genome is rescued by 2 integrated transgenes. snt-1(genomic; B-stop) = complete snt-1 genomic region with an in-frame stop codon engineered into exon 6B; also referred to as "snt-1(A only)." snt-1(genomic; A-stop) = complete snt-1 genomic region with an in-frame stop codon engineered into exon 6A; also referred to as "snt-1(B only)." Reference: Mathews EA, et al. Mol Cell Neurosci. 2007 Apr;34(4):642-52.
RM3286 snt-1(md290) II; unc-41(e268) V. C. elegans Unc.
RM3657 snt-1(md290) II; unc-41(md152) V. C. elegans Very uncoordinated and slow growing.