Caenorhabditis Genetics Center (CGC)

Variation Information: n498

Namen498 View on WormBase
Species C. elegans
Genetic positionIV:4.58 +/- 0.000 cM
Genomic positionIV: 10338870..10338870
Protein changeK11E8.1b K11E8.1b K11E8.1b K11E8.1d K11E8.1d K11E8.1e K11E8.1e K11E8.1f K11E8.1f K11E8.1g K11E8.1g K11E8.1h K11E8.1h K11E8.1i K11E8.1k K11E8.1l K11E8.1r Substitution

Strains carrying this variation

Strain Genotype Species Description
MT1092 unc-43(n498) IV. C. elegans Gain of function allele. Small, almost paralyized. Egl. Semi-dominant. daf-C at 27C.
MT2598 unc-43(n498n1179) IV. C. elegans
MT2605 unc-43(n498n1186) IV. C. elegans
PJ1182 unc-43(n498) IV; ccIs55 V; njEx38. C. elegans ccIs55 [unc-54::lacZ + sup-7(st5)] V. njEx38 [unc-54p::daf-2(+) + goa-1p::GFP + rol-6(su1006)]. Rollers. Pick Rollers to maintain. unc-43 gain-of-function. Progressive paralysis.
PJ1305 unc-43(n498j038) IV; ccIs55; njEx38. C. elegans ccIs55 [unc-54::lacZ + sup-7(st5)] V. njEx38 [unc-54p::daf-2(+) + goa-1p::GFP + rol-6(su1006)]. Rollers. Pick Rollers to maintain. unc-43 gain-of-function suppressed; not markedly small. Egl-d. Lethal @ 25C; short L1's do not survive. No GFP expression.
XM1007 fog-3(q443) I/hT2 [bli-4(e937) let-?(q782) qIs48] (I;III); unc-43(n498) IV. C. elegans Heterozygotes are Unc with pharyngeal GFP signal. Homozygous hT2[bli-4 let-? qIs48] are inviable. Homozygous unc-43(n498); fog-3(q443) animals are females.