Variation Information: tm1145
| Name | tm1145 View on WormBase |
|---|---|
| Species | C. elegans |
| Genetic position | III:-4.25 +/- 0.000 cM |
| Genomic position | III: 3861889..3862557 |
| Protein change | C36A4.8a C36A4.8c Deletion |
Strains carrying this variation
| Strain | Genotype | Species | Description |
|---|---|---|---|
| DW102 | brc-1(tm1145) III. | C. elegans | Homozygous viable. Weak Him phenotype (2-3%). Extremely sensitive to ionizing radiation and other DNA damaging agents. |
| NB390 | hsr-9(ok759) I; brc-1(tm1145) III. | C. elegans | Reduced apoptosis after gamma-ray treatment compared to N2. Double mutant exhibits hypersensitivity to gamma rays similar to brc-1(tm1145) alone. Reference: Ryu JS, et al; PLoS One. (In Press). |