Variation Information: ok758

Nameok758 View on WormBase
Species C. elegans
Genetic positionI:3.02 +/- 0.000 cM
Genomic positionI: 8663296..8664636
Protein changeF39H2.4 F39H2.4 Deletion

Strains carrying this variation

Strain Genotype Species Description
CA1218 syp-3(ok758) I; ieSi11 II; unc-119(ed3) III. C. elegans ieSi11 [syp-3p::EmeraldGFP::syp-3::syp-3 3'UTR + Cbr-unc-119(+)] II. ieSi11 was inserted into ttTi5605 II using MosSCI. Expression of GFP::SYP-3 largely complements syp-3(ok758), but some meiotic nondisjunction is detected above the N2 background (85% embryonic viability; ~1% male self-progeny;). GFP::SYP-3 expression is readily detected in spermatocytes and oocytes in the germline, and localizes to the interface between paired homologous chromosomes during most of meiotic prophase. Reference: Rog O, Dernburg AF. Cell Rep. 2015 Mar 10. pii: S2211-1247(15)00178-3.
CV2 syp-3(ok758)/hT2 [bli-4(e937) let-?(q782) qIs48] (I;III). C. elegans Heterozygotes are WT and GFP+. Segregate syp-3(ok758) homozygotes that are non-GFP and lay mostly dead eggs; these mutants lack synaptonemal complex formation during meiosis. Homozygous hT2[bli-4 let-? qIs48] animals are inviable.
VC588 syp-3(ok758) I. C. elegans F39H2.4. Variable morphology. Often wild type, often Dpyish, with frequent morphological defects (abnormal larvae, arrested larvae, sterility, vulval defects). Attribution: This strain was provided by the C. elegans Reverse Genetics Core Facility at the University of British Columbia, which is part of the international C. elegans Gene Knockout Consortium, which should be acknowledged in any publications resulting from its use. Paper_evidence WBPaper00041807