Caenorhabditis Genetics Center (CGC)

Variation Information: e669

Namee669 View on WormBase
Species C. elegans
Genetic positionII:23.31 +/- 0.000 cM
Genomic positionII: 14657911..14657911
Protein changeZC101.2a ZC101.2c ZC101.2d ZC101.2e ZC101.2f ZC101.2i ZC101.2j ZC101.2k ZC101.2l ZC101.2m ZC101.2n ZC101.2o ZC101.2r Substitution

Strains carrying this variation

Strain Genotype Species Description
CB669 unc-52(e669) II. C. elegans Unc-adults paralyzed. Dystrophic body muscle. Suppressed by sup-5 and sup-7. Null allele (?).
HE250 unc-52(e669su250) II. C. elegans Temperature sensitive Unc.
PJ104 cad-1(j1) unc-52(e669) II. C. elegans Unc-progressive paralysis. Reduced cathepsin.
SP1792 smu-1(mn415) I; unc-52(e669su250) II. C. elegans Non-Unc at all temperatures. See also WBPaper00004764.
SP1804 smu-2(mn416) unc-52(e669su250) II. C. elegans Non-Unc at all temperatures.
SP2668 smu-2(mn416) unc-52(e669su250) II; unc-36(e251) III; mnEx142. C. elegans mnEx142 [smu-2::GFP + unc-36(+)]. Animals carrying the array should be non-Unc-36 and should be Unc-52 (paralyzed, except for head, as late L4/adult - they look like hockey sticks) at 25 C. Without the array smu-2(mn416) suppresses unc-52(e669su250) so animals don't show the Unc-52 phenotype. Reference: Spartz AK, et al. Mol Cell Biol. 2004 Aug;24(15):6811-23.
SP2686 smu-2(mn416) unc-52(e669su250) II; unc-36(e251) III; mnEx151. C. elegans mnEx151 [smu-1::GFP + smu-2::3xHA + unc-36(+)]. Animals carrying the array should be non-Unc-36 and should be Unc-52 (paralyzed, except for head, as late L4/adult - they look like hockey sticks) at 25 C. Without the array smu-2(mn416) suppresses unc-52(e669su250) so animals don't show the Unc-52 phenotype. Reference: Spartz AK, et al. Mol Cell Biol. 2004 Aug;24(15):6811-23.
SP2693 smu-2(mn416) unc-52(e669su250) II; unc-36(e251) III; mnIs66. C. elegans mnIs66 [smu-2::HA + unc-36(+)]. Strain should be non-Unc-36 and should be Unc-52 (paralyzed, except for head, as late L4/adult - they look like hockey sticks) at 25 C. Reference: Spartz AK, et al. Mol Cell Biol. 2004 Aug;24(15):6811-23.