Variation Information: e1348

Namee1348 View on WormBase
Species C. elegans
Genetic positionII:0.59 +/- 0.000 cM
Genomic positionII: 7861183..7861183
Protein changeT09A5.10 T09A5.10 Substitution

Strains carrying this variation

Strain Genotype Species Description
CB2744 lin-5(e1348)/dpy-10(e128) II. C. elegans Heterozygotes are WT. Segregates Dpy. Segregates sterile Unc--Unc cannot back. Balanced well.
SV13 lin-5(e1348)/mnC1 [dpy-10(e128) unc-52(e444)] II. C. elegans Heterozygotes are WT and segregate WT, Stu and DpyUncs. Molecular lesion: amber mutation terminating translation at amino acid 159. DNA replication continues in the absence of mitosis. Mutants enter mitotis at the normal time and form bipolar spindles, but fail chromosome alignment at the metaphase plate, sister chromatid separation and cytokinesis.