Variation Information: e185

Namee185 View on WormBase
Species C. elegans
Genetic positionIII:-1.63 +/- 0.000 cM
Genomic positionIII: 5476405..5476405
Protein changeF48E8.1a F48E8.1b F48E8.1c Substitution

Strains carrying this variation

Strain Genotype Species Description
ATD3 lon-1(e185) par-3(e2074) unc-119(ed3) III; zuIs45 V; sDp3(III;f) C. elegans zuIs45 [nmy-2p::nmy-2::GFP + unc-119(+)] V. Pick wild-type to maintain. Worms carrying the sDp3 duplication are wild-type; animals that have lost the duplication are Lon Par (maternal effect lethal). Cross of JJ1473 and KK237. Unknown if unc-119(ed3) is still present or homozygous in background. Reference: Small LE & Dawes AT. Mol Biol Cell. 2017 Aug 1;28(16):2220-2231.
CB185 lon-1(e185) III. C. elegans Long. Abnormal bursae. Epistatic to Small. Recessive. M-MATING-NO SUCCESS.
CB1918 lon-1(e185) unc-32(e189) III. C. elegans Long. Unc. Linked closely.
CB2206 lon-1(e185) daf-4(e1364) unc-32(e189) III. C. elegans Temperature sensitive dauer constitutive. Long. Unc. Linked closely.
CB2305 lon-1(e185) sup-5(e1464) III. C. elegans Lon, slow-growing. Very poor growth at less than 20C.
DR1096 lon-1(e185) unc-36(e251) III. C. elegans Very long, thin, and slow moving.
EU918 lon-1(e185) par-3(it71)/qC1 [dpy-19(e1259) glp-1(q339)] III; spn-4(or191) V. C. elegans Temperature sensitive spn-1. Maintain at 15C. Lethal at 25C. Heterozygotes are WT and segregate WT, Lon which give only dead eggs at all temperatures, and Sterile Dpys(ts).
JJ1600 par-3(it71) lon-1(e185) III; him-8(e1489) IV; zuIs20. C. elegans zuIs20 [par-3p::par-3::ZF1::GFP + unc-119(+)]. Lon. Him. GFP-tagged PAR-3 that is degraded in early embryonic somatic cells. Rescues the Par phenotype of par-3(it71). Delayed endodermal cell gastrulation. Reference: Nance J, Munro EM, Priess JR. Development. 2003 Nov;130(22):5339-50.
JT5516 saDf1/lon-1(e185) III. C. elegans Heterozygotes are WT and segregate WT, Lon and dead eggs. Hets are slow growing and sick.
KK237 lon-1(e185) par-3(e2074) III; sDp3 (III;f). C. elegans WT sDp3-bearing animals segregate WT and lon-1 par-3 homozygotes that lay eggs that don't hatch. par-3 exhibits mildly ts penetrance in homozygotes. Strict maternal effect. Received new stock 3/01.
KK241 lon-1(e185) par-3(it62) III; sDp3 (III;f). C. elegans Animals with the Duplication are WT. Animals which have lost the Duplication are Lon and throw dead eggs.
KK571 lon-1(e185) par-3(it71)/qC1 [dpy-19(e1259) glp-1(q339)] III. C. elegans Heterozygotes are WT and segregate WT, Dpy Steriles, and Lon which give only dead eggs.
MT1803 lin-8(n111) II; lon-1(e185) lin-37(n758) III. C. elegans Long. Muv.
MT405 dpy-1(e1) lon-1(e185) III. C. elegans
MT4979 lon-1(e185) ced-6(n1813) unc-32(e189) ced-7(n1892) III. C. elegans ced-6(n1813): dead cells persist, maternal rescue of embryonic. Unc. Long.
MT4981 lon-1(e185) ced-6(n1813) III; ced-10(n1993) IV. C. elegans ced-10(n1993): cell corpses unengulfed. Long.
RL67 lon-1(e185) let-711(it150) unc-32(e189)/qC1 [dpy-19(e1259) glp-1(q339)] III. C. elegans Heterozygotes are WT and segregate WT, Dpy Steriles, and Lon Uncs which are temperature sensitive maternal effect lethals. Embryos from homozygyous it150 hermaphrodites have spindle orientation defects at second and third cleave at 25C.