Variation Information: e15

Namee15 View on WormBase
Species C. elegans
Genetic positionIV:3.29 +/- 0.000 cM
Genomic positionIV: 7201523..7201523
Protein changeR13A1.4a R13A1.4b R13A1.4c R13A1.4d Substitution

Strains carrying this variation

Strain Genotype Species Description
CB15 unc-8(e15) IV. C. elegans Unc.
DR641 ama-1(m118m221) unc-8(e15)/nT1 IV; +/nT1 V. C. elegans Heterozygotes are semi-Unc and segregate semi-Unc and Vul and dead eggs. (Does not segregate Unc homozygotes because linked to the unc is a lethal in the amanitin gene.)
DR645 ama-1(m118) unc-8(e15) IV. C. elegans
MP130 sup-40(lb130)/+ I; unc-8(e15) IV; egl-1(n487) V. C. elegans lb130/+ dominantly suppresses the e15 backing defect and causes recessive sterility. Three phenotypes are present in this strain: backing steriles (lb130 homozygotes), backing fertiles which are bloated (heterozygotes), and non-backing coiled Unc animals which are fertile and bloated (sup-40(+)). Maintain strain by picking fertile animals which can back. egl-1(n487) is included in the strain to facilitate identification of lb130 homozygotes, which grow slowly; their sterility contrasts with the bloating of lb130/+ heterozygotes.
MP145 unc-8(e15lb145) IV. C. elegans Intragenic unc-8 revertant. Appears wild type. Probable null allele.
MP150 unc-8(e15) IV; lbEx9. C. elegans lbEx9 [R31A1(cosmid) + rol-6(su1006)]. Pick non-Unc Rol to maintain. This strain was obtained by co-injection of plasmid pRF4 and cosmid R13A1 into gonads of unc-8(e15) animals. Reference: Shreffler W, Wolinsky E. Behav Genet. 1997 May;27(3):211-21.
MP151 unc-8(e15) IV; sup-42(lb88) X. C. elegans WT. lb88 is a recessive X-linked suppressor of unc-8 dominant mutations.
MP152 dpy-13(e184) unc-8(e15lb55) IV. C. elegans Dpy.
MP154 unc-8(e15) IV; egl-15(n484) sup-42(lb88) X. C. elegans Egl. Unc slightly suppressed; the animals will usually back some. [unc-8(e15); egl-15(n484) animals are extremely Unc and will not back.]