Variation Information: sc8

Namesc8 View on WormBase
Species C. elegans
Genetic positionV:4.01 +/- 0.000 cM
Genomic positionV: 12354046..12354046
Protein changeF23H12.4a F23H12.4b Substitution

Strains carrying this variation

Strain Genotype Species Description
ATD1 unc-119(ed3) III; sqt-3(sc8) par-1(b274) V/nT1[unc-?(n754) let-?] (IV;V); zuIs45 V. C. elegans zuIs45 [nmy-2p::nmy-2::GFP + unc-119(+)] V. Balanced heterozygotes are Unc and segregate Unc (heterozygotes), Rol Par (sqt-3 par-1 homozygotes; maternal effect lethal), and dead eggs (nT1 homozygotes). NMY-2::GFP is expressed in the germline and somatic gonad. Cross of JJ1473 and KK288. Unknown if unc-119(ed3) is still present or homozygous in background. Reference: Small LE & Dawes AT. Mol Biol Cell. 2017 Aug 1;28(16):2220-2231.
BE8 sqt-3(sc8) V. C. elegans Adults and L4 animals roll left. Recessive. M-MATING++ 1-10%WT. PKA rol-4.
DA869 sqt-3(sc8) lin-25(n545) him-5(e1467) unc-76(e911) V. C. elegans Roller. Unc. Vulvaless. Throws males. sc8 previously called rol-4(sc8).
GS807 unc-32(e189) lin-12(n676n930) III; sqt-3(sc8) sel-1(e1948) V. C. elegans RollerUnc. At 25C e1948 recessively suppresses the Egl phenotype of n676n930. At 15C a high percentage of hermaphrodites have a 0 AC-Egl phenotype. e1948 recessively suppresses vulval lineage defects and proximal mitosis. sc8 previously called rol-4(sc8). See also WBPaper00002448. Do not distribute this strain; other labs should request it from the CGC. This strain cannot be distributed to commercial organizations. This strain cannot be used for any commercial purpose or for work on human subjects.
JR113 sma-1(e30) unc-76(e911) wDf2/sqt-3(sc8) unc-61(e228) V. C. elegans Heterozygotes are WT and segregate WT, RolUncs and dead eggs. Homozygous wDf1 embryos arrest uniformly as unenclosed balls of differentiated cells. wDf2 formerly called zen-1(w1). sc8 previously called rol-4(sc8).
JR728 sqt-3(sc8) unc-61(e228)/wDf4 V. C. elegans Pick WT to maintain. Throws WT, Roller Uncs and dead eggs. wDf4 arrests as dead eggs with no gut. sc8 previously called rol-4(sc8).
KK288 sqt-3(sc8) par-1(b274) V/nT1 [unc-?(n754) let-?] (IV;V). C. elegans Heterozygotes are Unc and segregate Unc, RolPar (adult homozygotes lay eggs that don't hatch) and dead eggs. nT1[unc-?(n754) let-?] is dominant Unc and recessive lethal. Strict maternal effect. sc8 previously called rol-4(sc8).
MT5439 sqt-3(sc8) unc-76(e911) V; lon-2(e678) xol-1(y70) X. C. elegans Roller. Long. Unc. XO Lethal. sc8 previously called rol-4(sc8).
OCF13 lpin-1(ok2761)/sqt-3(sc8) unc-61(e228) V; ltIs37 IV; jjIs1092. C. elegans jjIs1092 [(pNUT1) npp-1::GFP + unc-119(+)]. ltIs37 [pie-1p::mCherry::his-58 + unc-119(+)] IV. Heterozygotes are wildtype with GFP+ and mCherry+. lpin-1(ok2761) homozygotes die as L1 larvae. Also segregates Unc Rol.