Variation Information: sc8

Namesc8 View on WormBase
Species C. elegans
Genetic positionV:4.01 +/- 0.000 cM
Genomic positionV: 12354046..12354046
Protein changeF23H12.4a F23H12.4b Substitution

Strains carrying this variation

Strain Genotype Species Description
ATD1 unc-119(ed3) III; sqt-3(sc8) par-1(b274) V/nT1[unc-?(n754) let-?] (IV;V); zuIs45 V. C. elegans zuIs45 [nmy-2p::nmy-2::GFP + unc-119(+)] V. Balanced heterozygotes are Unc and segregate Unc (heterozygotes), Rol Par (sqt-3 par-1 homozygotes; maternal effect lethal), and dead eggs (nT1 homozygotes). NMY-2::GFP is expressed in the germline and somatic gonad. Cross of JJ1473 and KK288. Unknown if unc-119(ed3) is still present or homozygous in background. Reference: Small LE & Dawes AT. Mol Biol Cell. 2017 Aug 1;28(16):2220-2231.
BE8 sqt-3(sc8) V. C. elegans Adults and L4 animals roll left. Recessive. M-MATING++ 1-10%WT. PKA rol-4.
DA869 sqt-3(sc8) lin-25(n545) him-5(e1467) unc-76(e911) V. C. elegans Roller. Unc. Vulvaless. Throws males. sc8 previously called rol-4(sc8).
GS807 unc-32(e189) lin-12(n676n930) III; sqt-3(sc8) sel-1(e1948) V. C. elegans RollerUnc. At 25C e1948 recessively suppresses the Egl phenotype of n676n930. At 15C a high percentage of hermaphrodites have a 0 AC-Egl phenotype. e1948 recessively suppresses vulval lineage defects and proximal mitosis. sc8 previously called rol-4(sc8). See also WBPaper00002448. Do not distribute this strain; other labs should request it from the CGC.
JR113 sma-1(e30) unc-76(e911) wDf2/sqt-3(sc8) unc-61(e228) V. C. elegans Heterozygotes are WT and segregate WT, RolUncs and dead eggs. Homozygous wDf1 embryos arrest uniformly as unenclosed balls of differentiated cells. wDf2 formerly called zen-1(w1). sc8 previously called rol-4(sc8).
JR728 sqt-3(sc8) unc-61(e228)/wDf4 V. C. elegans Pick WT to maintain. Throws WT, Roller Uncs and dead eggs. wDf4 arrests as dead eggs with no gut. sc8 previously called rol-4(sc8).
KK288 sqt-3(sc8) par-1(b274) V/nT1 [unc-?(n754) let-?] (IV;V). C. elegans Heterozygotes are Unc and segregate Unc, RolPar (adult homozygotes lay eggs that don't hatch) and dead eggs. nT1[unc-?(n754) let-?] is dominant Unc and recessive lethal. Strict maternal effect. sc8 previously called rol-4(sc8).
MT5439 sqt-3(sc8) unc-76(e911) V; lon-2(e678) xol-1(y70) X. C. elegans Roller. Long. Unc. XO Lethal. sc8 previously called rol-4(sc8).
OCF13 lpin-1(ok2761)/sqt-3(sc8) unc-61(e228) V; ltIs37 IV; jjIs1092. C. elegans jjIs1092 [(pNUT1) npp-1::GFP + unc-119(+)]. ltIs37 [pie-1p::mCherry::his-58 + unc-119(+)] IV. Heterozygotes are wildtype with GFP+ and mCherry+. lpin-1(ok2761) homozygotes die as L1 larvae. Also segregates Unc Rol.