Variation Information: e51

Namee51 View on WormBase
Species C. elegans
Genetic positionI:2.07 +/- 0.000 cM
Genomic positionI: 7434408..7434408
Protein change Substitution

Strains carrying this variation

Strain Genotype Species Description
AMH61 unc-13(e51) I; ddi-1(ok1468) IV. C. elegans ddi-1 also known as vsm-1.
BC110 dpy-14(e188) unc-13(e51) let-85(s142)/unc-15(e73) I. C. elegans Heterozygotes are WT and segregate WT, Unc and DpyUncLets. Lethal at L1. Maintain by picking WT.
BC112 dpy-14(e188) unc-13(e51) let-82(s85)/unc-15(e73) I. C. elegans Heterozygotes are WT and segregate more WT, paralyzed Unc, and DpyUncLet (DpyUnc Larvae are abnormal). Maintain by picking WT.
BC115 dpy-14(e188) unc-13(e51) let-81(s88)/unc-15(e73) I. C. elegans Heterozygotes are WT and segregate more WT, paralyzed Unc and DpyUncLethals. The DpyUncLets are abnormal larvae and die in early larval development. Pick WT to maintain.
BC123 dpy-14(e188) unc-13(e51) let-84(s91)/unc-15(e73) I. C. elegans Heterozygotes are WT and segregate more WT, paralyzed Unc and DpyUncLet. The DpyUncs are abnormal larvae that die in late larval development. Pick WT to maintain.
BC124 dpy-14(e188) unc-13(e51) unc-37(s80)/unc-15(e73) I. C. elegans Heterozygotes are WT and segregate more WT, paralyzed Unc and DpyUncLet. The DpyUncLet larvae are abnormal. Pick WT to maintain.
BC125 dpy-14(e188) unc-13(e51) let-79(s81)/unc-15(e73) I. C. elegans Heterozygotes are WT and segregate more WT, paralyzed Unc and DpyUncLethal. The DpyUncs are abnormal larvae that die in early larval development. Pick WT to maintain. Note 5/92: probably has lost dpy-14.
BC148 dpy-14(e188) let-75(s101) unc-13(e51)/unc-15(e73) I. C. elegans Heterozygotes are WT and segregate more WT, paralyzed Unc and DpyUncLethals. The DpyUncs are abnormal larvae that die in early larval development (L1). Pick WT to maintain. Previously called myo-1(s101).
BC149 dpy-14(e188) unc-13(e51) let-83(s97)/unc-15(e73) I. C. elegans Heterozygotes are WT and segregate more WT, paralyzed Unc and DpyUncLethals. The DpyUnc are abnormal larvae which die in early larval development. Pick WT to maintain.
BC157 dpy-14(e188) unc-13(e51) let-80(s96)/unc-15(e73) I. C. elegans Heterozygotes are WT and segregate more WT, paralyzed Unc and Lethal DpyUncs. Lethal early larval. Pick WT to maintain.
BC159 dpy-5(e61) unc-13(e51) I; sDp1 (I;f). C. elegans Animals with the duplication are WT. Animals which have lost the duplication are DpyUnc. Segregates 2% males. The males are sterile. The duplication is homozygous lethal.
BC160 dpy-14(e188) unc-13(e51) let-87(s106)/unc-15(e73) I. C. elegans Heterozygotes are WT and segregate WT, paralyzed Unc and DpyUncLethal. Lethal early larval (L1). Maintain by picking WT.
BC162 dpy-14(e188) unc-13(e51) let-88(s132)/unc-15(e73) I. C. elegans Heterozygotes are WT and segregate WT, paralyzed Unc and DpyUncLethal. The DpyUncs are abnormal larvae which die in early larval development. Pick WT to maintain.
BC165 dpy-14(e188) unc-13(e51) let-89(s133)/unc-15(e73) I. C. elegans Heterozygotes are WT and segregate WT, paralyzed Unc and DpyUncLethal. Lethal early larval. Maintain by picking WT.
BC184 dpy-14(e188) unc-13(e51) bli-4(s90)/unc-15(e73) I. C. elegans Heterozygotes are WT and segregate WT, paralyzed Unc and DpyUncLethals. The DpyUncs are abnormal larvae which die in late larval development. Pick WT to maintain. s90 previously called let-77. See also WBPaper00003507. CGC received new stock 3/01.
BC215 dpy-14(e188) unc-13(e51) let-78(s82)/unc-15(e73) I. C. elegans Heterozygotes are WT and segregate more WT, paralyzed Unc and DpyUncLethals. The DpyUncs are abnormal larvae which die in late larval development. Pick WT to maintain.
BC220 dpy-14(e188) unc-13(e51) let-90(s140)/unc-15(e73) I. C. elegans Heterozygotes are WT and segregate WT, paralyzed Unc and DpyUncLethal. The DpyUncs are abnormal larvae. Pick WT to maintain.
BC244 dpy-14(e188) let-86(s141) unc-13(e51)/unc-15(e73) I. C. elegans Heterozygotes are WT and segregate more WT, paralyzed Unc and DpyUncLethals. The DpyUncs are abnormal larvae which die in early larval development. Pick WT to maintain.
BC455 unc-15(e73) unc-13(e51) I. C. elegans Paralysed Unc.
BS3156 unc-13(e51) gld-1(q485)/hT2 [dpy-18(h662)] I; +/hT2 [bli-4(e937)] III. C. elegans Heterozygotes are wild-type and segregate WT heterozygotes, Unc (unc-13 gld-1 homozygotes), and Dpy (hT2 homozygotes; the bli-4 mutation is suppressed by dpy-18). XX Uncs have tumorous germline and are sterile; XO Uncs are cross fertile (though they don't mate due to the Unc mutation). q485 is the canonical allele of gld-1. It behaves like deletions of the locus in complementation tests and thus is genetically null. Molecularly, it is a deletion of 82 bases and fails to produce gld-1 RNA and protein.
BS585 unc-13(e51) ozDf5 I; nDp4 (I;V)/+. C. elegans Strain gives WT hermaphrodites and dead eggs.
CB51 unc-13(e51) unc-122(n2916) I. C. elegans Unc. See WBPaper00003781 regarding the unc-122 mutation.
CGC138 unc-13(e51)/hT1 I; dpy-11(e224)/hT1 [unc-42(e270) umnIs79] V. C. elegans umnIs79 [myo-2p::GFP + NeoR, I: 6284001] I. Pick wild-type GFP+ to maintain. Heterozygotes are wild-type GFP+, and segregate wild-type GFP+, DpyUnc, arrested hT1 homozygotes (GFP+), and dead eggs. Maintain by picking wild-type GFP+. Derived by insertion of myo-2p::GFP transgene into hT1 balancer in parental strain KR1037 using CRISPR/Cas9.
CGC139 unc-13(e51)/hT1 I; dpy-11(e224)/hT1 [unc-42(e270) umnIs80] V. C. elegans umnIs80 [myo-2p::mKate2 + NeoR, I: 6284001] I. Pick wild-type mKate2+ to maintain. Heterozygotes are wild-type mKate2+, and segregate wild-type mKate2+, DpyUnc, arrested hT1 homozygotes (mKate2+), and dead eggs. Maintain by picking wild-type mKate2+. Derived by insertion of myo-2p::mKate transgene into hT1 balancer in parental strain KR1037 using CRISPR/Cas9.
CGC29 unc-13(e51)/hT1 [umnIs18] I; dpy-11(e224)/hT1 [unc-42(e270)] V. C. elegans umnIs18 [myo-2p::GFP + NeoR, V: 1005689 (intergenic)] I. Heterozygotes are wild-type GFP+, and segregate wild-type GFP+, Dpy Unc, arrested hT1 homozygotes, and dead eggs. Maintain by picking wild-type GFP+. Derived by insertion of myo-2p::GFP transgene into hT1 balancer in parental strain KR1037 using CRISPR/Cas9.
CGC75 unc-13(e51)/hT1 [umnIs58] I; dpy-11(e224)/hT1 [unc-42(e270)] V. C. elegans umnIs58 [myo-2p::mKate2 + NeoR, V: 1005689 (intergenic)] V. Pick wild-type mKate2+ to maintain. Heterozygotes are wild-type mKate2+, and segregate wild-type mKate2+, DpyUnc, arrested hT1 homozygotes (mKate2+), and dead eggs. Maintain by picking wild-type mKate2+. Derived by insertion of myo-2p::mKate2 transgene into hT1 balancer in parental strain KR1037 using CRISPR/Cas9.
DR168 unc-13(e51) daf-8(e1393) I. C. elegans Temperature sensitive dauer constitutive. Unc. Semi-paralyzed. Closely linked.
DR435 dpy-5(e61) unc-13(e51) I. C. elegans Dpy. Unc.
EM598 hlh-2(bx115) unc-13(e51) I; him-5(e1490) V. C. elegans Paralyzed Unc. Throws males. hlh-2(bx115) has no phenotype in this background.
EU707 air-2(or207) unc-13(e51) I. C. elegans Temperature sensitive. Grow at permissive temperature of 15C. Fully penetrant cytokinesis defect at the restrictive temperature of 25C. Semi-dominant Unc.
GS305 evl-17(ar94)/dpy-5(e61) unc-13(e51) I. C. elegans Heterozygotes are WT and segregate WT, DpyUncs and Steriles which have an everted vulva. Do not distribute this strain; other labs should request it from the CGC. This strain cannot be distributed to commercial organizations. This strain cannot be used for any commercial purpose or for work on human subjects.
GS307 dpy-5(e61) cye-1(ar95)/unc-13(e51) I. C. elegans Heterozygotes are WT and segregate WT, Uncs and Sterile Dpys which have an everted vulva. ar95 previously called sel-10(ar95). See also WBPaper00004382. Do not distribute this strain; other labs should request it from the CGC. This strain cannot be distributed to commercial organizations. This strain cannot be used for any commercial purpose or for work on human subjects.
GS454 evl-9(ar121)/dpy-5(e61) unc-13(e51) I. C. elegans Heterozygotes are WT and segregate WT, DpyUncs and Steriles which have an everted vulva. Do not distribute this strain; other labs should request it from the CGC. This strain cannot be distributed to commercial organizations. This strain cannot be used for any commercial purpose or for work on human subjects.
JK1466 gld-1(q485)/dpy-5(e61) unc-13(e51) I. C. elegans Heterozygotes are WT and segregate WT, DpyUncs and steriles with a tumorous germline. Pick WT to maintain. Do not distribute this strain; other labs should request it from the CGC. This strain cannot be distributed to commercial organizations. This strain cannot be used for any commercial purpose or for work on human subjects.
JK1573 ces-1(n703) qDf6/dpy-14(e188) unc-13(e51) I. C. elegans Heterozygotes are Ces and grow very slowly and are often sterile. They segregate very early larval lethals, sickly DpyUncs and more hets. ces-1(n703) is dominant. Do not distribute this strain; other labs should request it from the CGC. This strain cannot be distributed to commercial organizations. This strain cannot be used for any commercial purpose or for work on human subjects.
JK1743 gld-2(q497)/dpy-5(e61) unc-13(e51) I. C. elegans Heterozygotes are WT and segregate WT, DpyUncs and Steriles. Do not distribute this strain; other labs should request it directly from the CGC. This strain cannot be distributed to commercial organizations. This strain cannot be used for any commercial purpose or for work on human subjects.
JK2208 gld-2(dx40)/dpy-5(e61) unc-13(e51) I. C. elegans Segregates wild-type hets, Ste dx40 homozygotes, and Dpy Uncs. Maintain by picking wild-type and checking for correct segregation. Do not distribute this strain; other labs should request it directly from the CGC. This strain cannot be distributed to commercial organizations. This strain cannot be used for any commercial purpose or for work on human subjects.
KR1037 unc-13(e51)/hT1 I; dpy-11(e224)/hT1 [unc-42(e270)] V. C. elegans Pick wild-type to maintain. Segregates wild-type, Dpy Unc, arrested hT1 homozygotes, and dead eggs. Reference: McKim KS, et al. Genetics. 1988 Dec;120(4):987-1001.
KR1567 dpy-14(e188) unc-13(e51) I; hDp73 (I;X;f?). C. elegans Dpy-14 phenotype. Segregates Dpy-14 and Dpy-14 Unc-13 progeny. Pick Dpy-14 and check for correct segregation of progeny to maintain. hDp73 probably linked to another chromosome. This strain was generated by the Genetic Toolkit project, which should be acknowledged in any publications resulting from its use: The Genetic Toolkit is funded by the NIH National Center for Research Resources (NCRR) (USA) to Ann M. Rose, David L. Baillie, and Donald L. Riddle. Report all experimental results to Ann Rose.
KR1704 dpy-14(e188) unc-13(e51) I; hDp68 (I;X;f). C. elegans Wild-type phenotype. Segregates WT and Dpy-14 Unc-13. Pick WT and check for correct segregation of progeny to maintain. This strain was generated by the Genetic Toolkit project, which should be acknowledged in any publications resulting from its use: The Genetic Toolkit is funded by the NIH National Center for Research Resources (NCRR) (USA) to Ann M. Rose, David L. Baillie, and Donald L. Riddle. Report all experimental results to Ann Rose.
KR1705 dpy-14(e188) unc-13(e51) I; hDp70 (I;X;f). C. elegans Wild-type phenotype. Segregates WT and Dpy-14 Unc-13. Pick WT and check for correct segregation of progeny to maintain. This strain was generated by the Genetic Toolkit project, which should be acknowledged in any publications resulting from its use: The Genetic Toolkit is funded by the NIH National Center for Research Resources (NCRR) (USA) to Ann M. Rose, David L. Baillie, and Donald L. Riddle. Report all experimental results to Ann Rose.
KR1706 dpy-14(e188) unc-13(e51) I; hDp66 (I;X;f). C. elegans Wild-type phenotype. Segregates WT and Dpy-14 Unc-13. Pick WT and check for correct segregation of progeny to maintain. This strain was generated by the Genetic Toolkit project, which should be acknowledged in any publications resulting from its use: The Genetic Toolkit is funded by the NIH National Center for Research Resources (NCRR) (USA) to Ann M. Rose, David L. Baillie, and Donald L. Riddle. Report all experimental results to Ann Rose.
KR1707 dpy-14(e188) unc-13(e51) I; hDp46 (I;X;f). C. elegans Wild-type phenotype. Segregates WT and Dpy-14 Unc-13. Pick WT and check for correct segregation of progeny to maintain. This strain was generated by the Genetic Toolkit project, which should be acknowledged in any publications resulting from its use: The Genetic Toolkit is funded by the NIH National Center for Research Resources (NCRR) (USA) to Ann M. Rose, David L. Baillie, and Donald L. Riddle. Report all experimental results to Ann Rose.
KR1718 dpy-14(e188) unc-13(e51) I; hDp45 (I;X;f). C. elegans Wild-type phenotype. Segregates WT and Dpy-14 Unc-13. Pick WT and check for correct segregation of progeny to maintain. This strain was generated by the Genetic Toolkit project, which should be acknowledged in any publications resulting from its use: The Genetic Toolkit is funded by the NIH National Center for Research Resources (NCRR) (USA) to Ann M. Rose, David L. Baillie, and Donald L. Riddle. Report all experimental results to Ann Rose.
KR1722 dpy-14(e188) unc-13(e51) I; hDp52 (I;X;f). C. elegans Wild-type phenotype. Segregates WT and Dpy-14 Unc-13. Pick WT and check for correct segregation of progeny to maintain. This strain was generated by the Genetic Toolkit project, which should be acknowledged in any publications resulting from its use: The Genetic Toolkit is funded by the NIH National Center for Research Resources (NCRR) (USA) to Ann M. Rose, David L. Baillie, and Donald L. Riddle. Report all experimental results to Ann Rose.
KR1725 dpy-14(e188) unc-13(e51) I; hDp44 (I;X;f). C. elegans Wild-type phenotype. Segregates WT and Dpy-14 Unc-13. Pick WT and check for correct segregation of progeny to maintain. This strain was generated by the Genetic Toolkit project, which should be acknowledged in any publications resulting from its use: The Genetic Toolkit is funded by the NIH National Center for Research Resources (NCRR) (USA) to Ann M. Rose, David L. Baillie, and Donald L. Riddle. Report all experimental results to Ann Rose.
KR1726 dpy-14(e188) unc-13(e51) I; hDp50 (I;X;f). C. elegans Dpy-14 phenotype, weaker than e188. Healthy, vigorous, segregates Dpy-14 and Dpy-14 Unc-13. Maintain by picking Dpy-14 and checking for correct segregation of progeny. This strain was generated by the Genetic Toolkit project, which should be acknowledged in any publications resulting from its use: The Genetic Toolkit is funded by the NIH National Center for Research Resources (NCRR) (USA) to Ann M. Rose, David L. Baillie, and Donald L. Riddle. Report all experimental results to Ann Rose.
KR1755 dpy-14(e188) unc-13(e51) I; hDp65 (I;X;f). C. elegans Dpy-14 phenotype. Slow-growing. Segregates Dpy-14 and Dpy-14 Unc-13. Maintain by picking Dpy-14 and checking for correct segregation of progeny. This strain was generated by the Genetic Toolkit project, which should be acknowledged in any publications resulting from its use: The Genetic Toolkit is funded by the NIH National Center for Research Resources (NCRR) (USA) to Ann M. Rose, David L. Baillie, and Donald L. Riddle. Report all experimental results to Ann Rose.
KR1787 unc-13(e51) I. C. elegans The origin of this strain is KR1082 via CB51. KR1082 was maintained on plates for a period of approximately two years. After this time, DNA was made and the Tc1 pattern examined. The number of Tc1s found in KR1787 was greater than that found in KR1082. Perhaps as many as 30 additional Tc1s were visible in excess of those normally seen in N2 strains.
KR1795 dpy-14(e188) unc-13(e51) I; hDp67 (I;X;f). C. elegans Wild-type phenotype. Segregates WT and Dpy-14 Unc-13. Pick WT and check for correct segregation of progeny to maintain. This strain was generated by the Genetic Toolkit project, which should be acknowledged in any publications resulting from its use: The Genetic Toolkit is funded by the NIH National Center for Research Resources (NCRR) (USA) to Ann M. Rose, David L. Baillie, and Donald L. Riddle. Report all experimental results to Ann Rose.