Variation Information: e156

Namee156 View on WormBase
Species C. elegans
Genetic positionIII:20.66 +/- 0.000 cM
Genomic positionIII: 12948395..12948395
Protein changeY37D8A.23a Y37D8A.23b Y37D8A.23c Substitution

Strains carrying this variation

Strain Genotype Species Description
BA606 spe-6(hc49) unc-25(e156) III; eDp6 (III;f). C. elegans Animals with the Duplication are WT. Animals without the Duplication are Unc and Sterile.
BW1535 dpy-18(e364) ctDf3 unc-25(e156)/qC1 [dpy-19(e1259) glp-1(q339)] III. C. elegans Heterozygotes are WT and segregate WT, DpySteriles and dead eggs. Maintain by picking WT.
BW1561 dpy-18(e364) nob-1(ct223) unc-25(e156) III; eDp6 (III;f). C. elegans Animals with the duplication are WT. Animals without the duplication are Nob (NO Back end; 100% lethal). Pick wild-type to maintain. The Dpy and Unc phenotypes are not visible in the Nob background. ct223 is recessive.
CB156 unc-25(e156) III. C. elegans Shrinker-contracts both dorsally and ventrally when prodded. Slow, poor backing. Slightly small.
DR104 dpy-18(e364) unc-25(e156) dnj-17(ju1162) III. C. elegans DpyUnc.
JJ532 pie-1(zu154) unc-25(e156)/qC1 [dpy-19(e1259) glp-1(q339)] III. C. elegans Heterozygotes are WT and segregate WT, Unc and DpySteriles. Uncs give only dead eggs. Maintain by picking WT.
ML456 ale-1(mc14)/spe-6(hc49) unc-25(e156) III. C. elegans Heterozygotes are WT and segregate WT, embryonic lethals (embryos fail to elongate) and Sterile Uncs. mc14 identified as a mutation that leads to abnormal lin-26 expression.
MT6184 unc-52(e444) II; unc-25(e156) dnj-17(ju1162) III; dpy-4(e1166) IV. C. elegans
RM2711 unc-25(e156) III; snf-11(ok156) V. C. elegans Superficially similar to unc-25 mutants (Shrinker, Exp, etc.), except that unc-25-dependent behaviors are not rescued by exogenous GABA. Reference: Mullen GP, et al. Mol Biol Cell. 2006 Jul;17(7):3021-30.
RM2715 snf-3(ok293) II; unc-25(e156) III. C. elegans Superficially similar to unc-25 mutants (Shrinker, Exp, etc.). GABA-dependent phenotypes are rescued by exogenous GABA. Reference: Mullen GP, et al. Mol Biol Cell. 2006 Jul;17(7):3021-30. Peden AS, et al. Nat Neurosci. 2013 Dec;16(12):1794-801.
RM2717 snf-3(ok293) II; unc-25(e156) III; snf-11(ok156) V. C. elegans Superficially the same as unc-25 mutants (Shrinker, Exp, etc.). Exogenous GABA does not rescue the unc-25-dependent expulsion deficit. See Mullen GP, et al. [Mol Biol Cell. 2006 Jul;17(7):3021-30.] for detailed description of snf-11 and unc-25; snf-11 phenotypes. See Peden AS, et al. [Nat Neurosci. 2013 Dec;16(12):1794-801]. for detailed description of snf-3 phenotypes.
SP1104 unc-25(e156) bli-5(e518) III. C. elegans Bli. Unc.