Variation Information: e224

Namee224 View on WormBase
Species C. elegans
Genetic positionV:-0.01 +/- 0.000 cM
Genomic positionV: 6512793..6512793
Protein changeF46E10.9 F46E10.9 Substitution

Strains carrying this variation

Strain Genotype Species Description
DM2407 hsp-1(ra807) IV; dpy-11(e224) V. C. elegans Dpy. hsp-1(ra807) is a missense allele that replaces the conserved Ala379 residue to a Val residue in the ATPase domain of the HSP-1 protein and fully suppresses the bent-head phenotype of unc-23(e25). Reference: Rahmani P, Rogalski T, Moerman DG. (2015) Worm. In press.
DR108 dpy-11(e224) unc-42(e270) V. C. elegans DpyUnc.
DR117 unc-15(e73) I; dpy-11(e224) V. C. elegans Dpy. Unc. Very slow movement.
DR118 unc-15(e73) I; dpy-11(e224) eDp22 V. C. elegans
DR119 unc-54(e1258) I; dpy-11(e224) wdDp1 V. C. elegans DPY.
DR181 unc-60(m35) dpy-11(e224) V. C. elegans Dpy. Unc-slow moving.
DR183 dpy-11(e224) daf-11(m47) V. C. elegans Temperature sensitive dauer constitutive. Dpy.
DR194 dpy-11(e224) daf-11(m47) unc-39(e257) V. C. elegans Temperature sensitive dauer constitutive. Leaky. Dpy. Unc.
DR238 dpy-11(e224) mec-9(e1494) V. C. elegans Dpy. Mechanosensory abnormal.
DR240 dpy-11(e224) unc-42(e270) daf-11(m84) V. C. elegans Temperature sensitive dauer constitutive. Dpy. Unc.
DR401 unc-15(e73) I; eDf1 eDp21/dpy-11(e224) V. C. elegans Heterozygotes are slow moving. Hets segregate DpyUncs. Hets segregate larval lethals (eDf1 eDp21 homozygotes).
EG1020 bli-6(sc16) IV; dpy-11(e224) V; lon-2(e678) X. C. elegans Dpy suppresses Bli and Lon. Strain appears to be only slightly Dpy. Useful for mapping, especially Unc mutations. Separately, dpy-11 causes dumpiness, bli-6 adult worms develop blisters on their bodies, and lon-2 worms are about 150% WT length.
FJ224 unc-31(e298) IV; dpy-11(e224) V. C. elegans
GE2001 xpf-1(e1487) II; unc-24(e138) IV/nT1(IV;V); dpy-11(e224) ccz-1(t2070) V/nT1 (IV;V). C. elegans Him. Wild-type heterozygotes segregate WT heterozygotes and Dpy Unc ccz-1 homozygotes (produce only arrested embryos). ccz-1 embryos have spindle orientation defects, accumulate vesicles, and problems engulfing apoptotic corpses. Reference: Nieto C, et al. J Cell Sci. 2010 Jun 15;123(Pt 12):2001-7.
GE2516 xpf-1(e1487) II; unc-24(e138) IV/nT1(IV;V); dpy-11(e224) ccz-1(t2071) V/nT1 (IV;V). C. elegans Him. Wild-type heterozygotes segregate WT heterozygotes and Dpy Unc ccz-1 homozygotes (produce only arrested embryos). ccz-1 embryos have spindle orientation defects, accumulate vesicles, and problems engulfing apoptotic corpses. Reference: Nieto C, et al. J Cell Sci. 2010 Jun 15;123(Pt 12):2001-7.
GS107 unc-32(e189) lin-12(n676n930) III; dpy-11(e224) sel-9(ar22) V. C. elegans DpyUnc. At 25C ar22 recessively suppresses the Egl defect of n676n930. At 15C ar22 dominantly suppresses the 2 AC-Egl phenotype of n676n930. Suppresses the vulval lineage defects and proximal mitosis defects of lin-12. Do not distribute this strain; other labs should request it from the CGC. This strain cannot be distributed to commercial organizations. This strain cannot be used for any commercial purpose or for work on human subjects.
GS370 evl-12(ar109)/dpy-11(e224) unc-42(e270) V. C. elegans Heterozygotes are WT and segregate WT, Steriles with an Everted Vul and DpyUncs. Received new stock 10/2003. Do not distribute this strain; other labs should request it from the CGC. This strain cannot be distributed to commercial organizations. This strain cannot be used for any commercial purpose or for work on human subjects.
GS384 fos-1(ar105)/dpy-11(e224) unc-42(e270) V. C. elegans Heterozygotes are WT and segregate WT, Steriles with an Everted Vul and DpyUncs. Do not distribute this strain; other labs should request it from the CGC. This strain cannot be distributed to commercial organizations. This strain cannot be used for any commercial purpose or for work on human subjects. ar105 previously called evl-5(ar105).
GS401 let-418(ar113)/unc-46(e177) dpy-11(e224) V. C. elegans Heterozygotes are WT and segregate WT, Steriles with an Everted Vul and DpyUncs. ar113 pka evl-11(ar113). Do not distribute this strain; other labs should request it from the CGC. This strain cannot be distributed to commercial organizations. This strain cannot be used for any commercial purpose or for work on human subjects.
GS402 let-418(ar114)/unc-46(e177) dpy-11(e224) V. C. elegans Heterozygotes are WT and segregate WT, DpyUncs and Steriles which have an everted vulva. ar114 pka evl-11(ar114). Do not distribute this strain; other labs should request it from the CGC. This strain cannot be distributed to commercial organizations. This strain cannot be used for any commercial purpose or for work on human subjects.
GZ491 dpy-11(e224) sas-5(t2033) V/nT1 [let-?(m435)] (IV;V). C. elegans
HH17 unc-60(m35) cdc-25.2(b262) dpy-11(e224) V. C. elegans Dpy. Unc. Temperature sensitive-maintain at 15C.
JCP152 dpy-11(e224) ccz-1(t2129) V; jcpEx2. C. elegans jcpEx2 [ced-1p::F58G11.6(genomic)::YFP::let-858 3'UTR + unc-119(+) + myo-2::GFP]. Maintain by picking GFP+. Individuals that lost the array produce only arrested embryos with spindle orientation defects, accumulate vesicles, and problems engulfing apoptotic corpses. Reference: Nieto C, et al. J Cell Sci. 2010 Jun 15;123(Pt 12):2001-7.
JCP169 dpy-11(e224) ccz-1(t2129) V; jcpEx3. C. elegans jcpEx3 [ccz-1p::ccz-1(genomic)::YFP::let-858 3'UTR + unc-119(+) + pha-1(+)]. Array rescues lethality. Individuals that lost the array produce only arrested embryos with spindle orientation defects, accumulate vesicles, and problems engulfing apoptotic corpses. Reference: Nieto C, et al. J Cell Sci. 2010 Jun 15;123(Pt 12):2001-7.
JCP53 dpy-11(e224) ccz-1(t2129) V/nT1 [qIs51] (IV;V). C. elegans Heterozygotes are WT with pharyngeal GFP signal, and segregate WT GFP, arrested nT1[qIs51] aneuploids, and non-GFP ccz-1 homozygotes (produce only arrested embryos with spindle orientation defects, accumulate vesicles, and problems engulfing apoptotic corpses). Homozygous nT1[qIs51] inviable. Pick WT GFP and check for correct segregation of progeny to maintain. Reference: Nieto C, et al. J Cell Sci. 2010 Jun 15;123(Pt 12):2001-7.
JJ746 +/nT1 IV; apx-1(zu183) dpy-11(e224)/nT1 V. C. elegans Heterozygotes are WT and segregate WT, Dpy, Vul and dead eggs. The Dpys give only dead eggs. apx-1 is a maternal effect lethal. zu183 is recessive.
JK2663 dpy-11(e224) mes-4(bn67) V/nT1 [unc-?(n754) let-? qIs50] (IV;V). C. elegans qIs50 is an insertion of ccEx9747 with markers: myo-2::GFP expressed brightly in the pharynx throughout development, pes-10::GFP expressed in embryos, and a gut promoter (F22B7.9) driving GFP in the intestine. Segregates non-glowing Dpys that are Mes (produce only sterile progeny) and glowing Unc heterozygotes. nT1[unc-?(n754) let-? qIs50] is also known as DnT1[qIs50]. qIs50 is apparently inserted on DnT1. qIs50 is somewhat dimmer than the similar qIs51. Do not distribute this strain; other labs should request it directly from the CGC. This strain cannot be distributed to commercial organizations. This strain cannot be used for any commercial purpose or for work on human subjects.
JK2958 nT1 [qIs51] (IV;V)/dpy-11(e224) unc-42(e270) V. C. elegans Segregates glowing heterozygotes and DpyUncs. nT1[qIs51] is probably homozygous lethal. qIs51 is an insertion of ccEx9747 with markers: myo-2::GFP expressed in the pharynx throughout development, pes-10::GFP expressed in the embryo, and a gut promoter F22B7.9::GFP expressed in the intestine. Crosses with this strain generate very few glowing hermaphrodite cross progeny and many glowing male cross progeny. Do not distribute this strain; other labs should request it directly from the CGC. This strain cannot be distributed to commercial organizations. This strain cannot be used for any commercial purpose or for work on human subjects.
JS71 dpy-11(e224) air-1(vw5) V/eT1 (III;V). C. elegans Heterozygotes are WT and segregate WT, Dpy Stu, Unc-36 (eT1 homozygotes) and dead eggs. Also weak Him.
KR1037 unc-13(e51)/hT1 I; dpy-11(e224)/hT1 [unc-42(e270)] V. C. elegans Pick wild-type to maintain. Segregates wild-type, Dpy Unc, arrested hT1 homozygotes, and dead eggs. Reference: McKim KS, et al. Genetics. 1988 Dec;120(4):987-1001.
LC105 unc-46(e177) dpy-11(e224) uIs69 V. C. elegans uIs69 [(pCFJ90) myo-2p::mCherry + unc-119p::sid-1]. Hypersensitive neuronal RNAi by feeding. Dpy, Unc. Maintain 15-20 degrees. [NOTE: uIs69 is closely linked and maps to the right of dpy-11. (C. Loer 08/2011)] Derived from (BC277 x N2 Male) x TU3401. Reference: Calixto et al. (2010) Nature Methods 7:554-9.
MT1000 unc-5(e53)/nT1 IV; dpy-11(e224)/nT1 V. C. elegans Heterozygotes are WT and segregate WT, DpyUnc, Vul and dead eggs. Maintain by picking WT.
MT1676 unc-70(n493) dpy-11(e224) V. C. elegans DpyUnc. Semidominant Unc.
MT20112 +/eT1 III; unc-46(e177) dpy-11(e224)/eT1 nIs267 V. C. elegans nIs267 [myo-2::GFP] integrated in or near eT1. Heterozygotes are wild-type and segregate WT, Dpy Unc, and Unc. Maintain by picking wild-type; check for presence of Unc progeny.
MT2583 dpy-11(e224) nDf32 V/eT1 (III;V). C. elegans Heterozygotes are WT (slightly Unc) and segregate WT, Unc-36 and dead eggs. Maintain by picking WT.
MT2590 +/eT1 III; dpy-11(e224) unc-70(n493n1171)/eT1 V. C. elegans Heterozygotes are WT and segregate WT, Unc-36 (eT1 homozygotes), arrested larvae (n493n1171 homozygotes) and dead eggs.
MT2591 +/eT1 III; dpy-11(e224) unc-70(n493n1172)/eT1 V. C. elegans Heterozygotes are WT and segregate WT, Unc-36 (eT1 homozygotes), arrested larvae (n493n1172 homozygotes) and dead eggs.
MT2592 +/eT1 III; dpy-11(e224) unc-70(n493n1173)/eT1 V. C. elegans Heterozygotes are WT and segregate WT, Unc-36 (eT1 homozygtes), arrested larvae (n493n1173 homozygotes) and dead eggs.
MT2867 unc-36(e251) III; unc-5(e53) IV; dpy-11(e224) V; lon-2(e678) lin-15B&lin-15A(n765) X. C. elegans
MT4446 unc-34(e566) unc-60(e677) dpy-11(e224) V. C. elegans Dpy. Unc.
MT464 unc-5(e53) IV; dpy-11(e224) V; lon-2(e678) X. C. elegans Mapping strain. DpyUnc.
NM1081 snb-1(js124)/dpy-11(e224) unc-68(r1158) V. C. elegans Heterozygotes are WT and segregate WT, DpyUncs and L1 lethals. js124 homozygotes arrest as L1 larvae that are very uncoordinated and tend to adopt a coiled position. js124 molecular lesion is an amber mutation at codon 50.
NW1619 dpy-11(e224) mig-6(ev700) V/eT1 (III;V). C. elegans Heterozygotes display abnormal distal tip cell migration detectable as clear patches in anterior and posterior. Heterozygotes segregate WT, Dpy, abnormal DTC migration, Unc, and dead eggs. Maintain by picking wild-type.
NW1623 dpy-11(e224) mig-6(ev788) V/eT1 (III;V). C. elegans Heterozygotes display partially penetrant (~10%) abnormal distal tip cell migration detectable as clear patches in anterior and posterior. Heterozygotes segregate WT, abnormal DTC migration, Unc, and dead eggs. Maintain by picking wild-type.
NW1625 dpy-11(e224) mig-6(e1931) V/eT1 (III;V). C. elegans Heterozygotes are wild-type and segregate WT, Dpy-Ste Unc, and dead eggs. Maintain by picking wild-type.
OH4329 lsy-6(ot71) dpy-11(e224) V; otEx2322. C. elegans otEx2322[gcy-14(prom1)::GFP + unc-122::GFP]. Faint ASE GFP expression (2 right). Expresses bright GFP in coelomocytes. Dpy.
OH4397 otIs151; lsy-6(ot71) dpy-11(e224) V; otEx2419. C. elegans otIs151 [ceh-36p::RFP + rol-6(su1006)]. Expresses RFP in AWCL/R and ASEL/R. otEx2419 [gcy-(prom1)::GFP + unc-122::GFP]. Bilateral expression of GFP in ASE. Expresses bright GFP in coelomocytes. Rollers. Dpy. Maintain by picking GFP+.
PD4589 dpy-11(e224) ceh-24(cc539) V. C. elegans Dpy. Deletion of entire ceh-24 gene except first five amino acids.
QP218 unc-34(e315) dpy-11(e224) rol-9(sc148) V. C. elegans Unc. Dpy. Rol(ts).
QP220 unc-60(m35) dpy-11(e224) rol-9(sc148) V. C. elegans Unc. Dpy. Rol(ts).