Variation Information: e224

Namee224 View on WormBase
Species C. elegans
Genetic positionV:-0.01 +/- 0.000 cM
Genomic positionV: 6512793..6512793
Protein changeF46E10.9 F46E10.9 Substitution

Strains carrying this variation

Strain Genotype Species Description
RW3570 unc-112(st562)/dpy-11(e224) unc-23(e25) V. C. elegans Heterozygotes are WT and segregate WT, DpyUnc and Pats. Maintain by picking WT and checking for correction segregation of progeny.
SP119 xpf-1(e1487) II; dpy-11(e224) V. C. elegans Dpy. Throws males.
SP1377 dpy-11(e224) V; lin-2(e1309) unc-7(mn384) xol-1(mn467) X. C. elegans Animals are DpyUncVul. Can mate at low frequency. N2 males X SP1377 fail to give male progeny. Weak unc-7 allele when not in lin-2 background.
SP298 dpy-11(e224) V; unc-3(e151) X; mnDp26 (X,V;f). C. elegans Pick WT to maintain. WT segregates DpyUnc and WT.
SS268 dpy-11(e224) mes-4(bn23) unc-76(e911) V/nT1 [unc-?(n754) let-?] (IV;V). C. elegans Heterozygotes are Unc (n754 is a dominant Unc and recessive lethal). Throws DpyUncs which give sterile progeny. The maternal effect sterility is 99% expressed, 100% strict, and is associated with 2% maternal effect embryonic lethality.
SS609 pgl-3(bn104) dpy-11(e224) V. C. elegans Dpy. Fertile at all temperatures.
SS615 pgl-1(bn101) unc-24(e138) IV; pgl-3(bn104) dpy-11(e224) V. C. elegans Dpy Unc. Temperature sensitive. Maintain at 15C. Grows very slowly.
SS617 pgl-1(ct131) him-3(e1147) unc-24(e138) IV; pgl-3(bn104) dpy-11(e224) V. C. elegans Throws males. Dpy. Unc. Mostly sterile at all temperatures, but a small fraction are fertile at low temperatures. Maintain at 15C.
SS731 pgl-2(bn123) III; pgl-3(bn104) dpy-11(e224) V. C. elegans Dpy. Fertile at all temperatures.
SS733 pgl-2(bn123) III; pgl-1(bn101) unc-24(e138) IV; pgl-3(bn104) dpy-11(e224) V. C. elegans Dpy. Unc. Mostly sterile at all temperatures, but a small fraction are fertile at low temperatures. Maintain at 15C.
TH37 dpy-11(e224) unc-23(e25) V. C. elegans Dpy. Unc.
TY832 yDf4/dpy-11(e224) unc-76(e911) V. C. elegans Heterozygotes are WT and segregate WT, DpyUnc and dead eggs. Maintain by picking WT.
VC362 unc-5(e53) IV/nT1 [qIs51] (IV;V); dpy-11(e224) V/nT1 [qIs51] (IV;V). C. elegans Morphological markers unc-5 and dpy-11 balanced by GFP-marked translocation. Heterozygotes are WT with pharyngeal GFP signal, and segregate WT GFP+, arrested nT1 aneuploid progeny, and GFP- unc-5; dpy-11 homozygotes. nT1[qIs51] homozygotes inviable. Pick GFP+ WT and check for correct segregation of progeny to maintain. Attribution: This strain was provided by the C. elegans Reverse Genetics Core Facility at the University of British Columbia, which is part of the International C. elegans Gene Knockout Consortium, which should be acknowledged in any publications resulting from its use. Paper_evidence WBPaper00041807
XE1037 geIs3 I; dpy-11(e224) V; oxIs12 X. C. elegans geIs3 [sir-2.1(+) + rol-6(su1006)] I. oxIs12 [unc-47p::GFP] X. GFP expression in GABA neurons. Rollers. Dpy. Reference: Byrne AB, et al. Neuron. 2014; 81(3):561-73.