AG166 |
mdf-2(av16) unc-17(e245) IV. |
C. elegans |
Reduced brood size. Reduced hatching. Slow growth. Larval lethal. Larval arrest. Bursts at vulva. Suppresses the mat-3 one-cell arrest at 25C. |
CB2110 |
unc-17(e245) IV; sup-2(e997) X. |
C. elegans |
Suppressed Unc. Movement almost WT. |
CB3031 |
unc-17(e245) IV; snb-1(e1563) V. |
C. elegans |
Dominant suppressor of Unc. Movement almost WT. |
CB5265 |
sup-1(e995e2636) III; unc-17(e245) IV; xol-1(y9) X. |
C. elegans |
Severely uncoordinated coiler, slow growing. Useful strain for selecting non-Sup-1 suppressors of unc-17(e245). Reference: Mathews et al. (2012) PMID: 23051648. |
CB7427 |
unc-17(e245) IV; eEx849. |
C. elegans |
eEx849 [C28H8.4(sdmV186E)]. unc-17 missense mutant suppressed by missense C28H8.4 transgene. Pick non-Unc hermaphrodites to maintain. Animals that have lost the array are severely Unc (coilers). Reference: Stroud et al (in preparation). |
CB7430 |
unc-17(e245) IV; eEx855. |
C. elegans |
eEx855 [erd-2(sdmV186E) + sur-5p::GFP]. unc-17 missense mutant partly suppressed by missense erd-2 (a.k.a. sup-2) transgene. Pick GFP+ (weak Unc) hermaphrodites to maintain. Animals that have lost the array are severely Unc (coilers). Reference: Stroud et al (in preparation). |
CB933 |
unc-17(e245) IV. |
C. elegans |
M-MATING-NO SUCCESS. UNC-Severe coiler at all stages-small and thin. SCORED EASILY. Suppressed by sup-1, sup-2, and snb-1. Resistant to lannate. See also CGC 1770. |
DR105 |
unc-17(e245) dpy-20(e1282) IV. |
C. elegans |
DpyUnc. |
DR1786 |
dpy-13(e184) unc-24(e138) IV; mDp4[unc-17(e245)] (IV;?). |
C. elegans |
WT phenotype. Segregates WT and DpyUncs. mDp4 carries dpy-13(+) and unc-24(+). Duplication may recombine with normal homologues. Presence of unc-17(e245) on mDp4 confirmed: got Unc-17 segregants after heat shock of this stock to generate males. Pick WT and check for segregation of progeny to maintain. |
MT4150 |
unc-17(e245) dpy-4(e1166) IV; him-5(e1490) V. |
C. elegans |
DpyUnc. Segregates males. |
MT628 |
dpy-9(e12) unc-17(e245) IV. |
C. elegans |
Dpy. Unc. |
RM3643 |
sup-1(e995 e2636) III; unc-17(e245) IV. |
C. elegans |
Indistinguishable from unc-17(e245) single mutants (small, slow-growing, coily uncoordinated, jerky going backward, aldicarb-resistant). For additional information, see descriptions of the RM908 unc-17(e245) IV and RM3671 sup-1(e995 e2636)) III single mutant strains. PCR methods for scoring e245, e995, and e2636 mutations in individual worms are presented in the Supporting Information File of Mathews et al., 2012. Derived by crossing RM908 (6x outcrossed) and RM3571 (6x outcrossed). Reference: Mathews EA, et al. Genetics. 2012 Dec;192(4):1315-25. |
RM3645 |
unc-17(e245) IV; snb-1(e1563) V. |
C. elegans |
Almost full suppression of all unc-17 mutant phenotypes; animals are superficially wild type in appearance, development, and behavior, and males mate well. For additional information, see descriptions of the RM908 unc-17(e245) IV and the RM3659 snb-1(e1563) V single mutant strains. Reference: Sandoval GM, et al. Nat Neurosci. 2006 May;9(5):599-601. |
RM3660 |
sup-1(e995) III; unc-17(e245) IV. |
C. elegans |
Almost full suppression of all unc-17 mutant phenotypes; animals are superficially wild type in appearance, development, and behavior, and males mate well. For additional information, see descriptions of the RM908 unc-17(e245) IV and the RM3670 sup-1(e995) III single mutant strains. PCR methods for scoring e245 and e995 mutations in individual worms are presented in the Supporting Information File of Mathews et al., 2012. Reference: Mathews EA, et al. Genetics. 2012 Dec;192(4):1315-25. |
RM908 |
unc-17(e245) IV. |
C. elegans |
Small, slow-growing, coily uncoordinated, jerky going backward, aldicarb- and lannate-resistant. Molecular details: G347R (gga>>aga) in the 9th transmembrane domain of the UNC-17 protein. PCR method for scoring the e245 mutation in individual worms is presented in the Supporting Information File of Mathews et al., 2012. |