Variation Information: e450

Namee450 View on WormBase
Species C. elegans
Genetic positionI:2.07 +/- 0.000 cM
Genomic positionI: 7435173..7435173
Protein change Substitution

Strains carrying this variation

Strain Genotype Species Description
KR1482 let-611(h826) dpy-5(e61) unc-13(e450) I; sDp2 (I;f). C. elegans Animals with the duplication are Unc. Animals which have lost the duplication are Dpy Unc and arrest in early-mid larval development.
KR1501 let-644(h839) dpy-5(e61) unc-13(e450) I; sDp2 (I;f). C. elegans Animals with the duplication are Unc. Animals which have lost the duplication are DpyUnc and arrest in late larval development.
KR1504 let-545(h842) dpy-5(e61) unc-13(e450) I; (rh??) X?; sDp2 (I;f). C. elegans Unc-13 phenotype. Segregates Uncs and lethal DpyUncs (h842 arrests as a sterile adult, and the unlinked mutation results in a tumorous gonad phenotype). Maintain by picking Unc-13 and checking for correct segregation of progeny.
KR1506 let-504(h844) dpy-5(e61) unc-13(e450) I; sDp2 (I;f). C. elegans Animals with the duplication are Unc. Animals which have lost the duplication are DpyUnc and arrest in early larval development.
KR1508 let-586(h846) dpy-5(e61) unc-13(e450) I; sDp2 (I;f). C. elegans Animals with the duplication are Unc. Animals which have lost the duplication are DpyUnc and arrest in mid larval development.
KR1511 let-587(h849) dpy-5(e61) unc-13(e450) I; sDp2 (I;f). C. elegans Animals with the duplication are Unc. Animals which have lost the duplication are DpyUnc and arrest in late larval development.
KR1524 let-525(h871) dpy-5(e61) unc-13(e450) I; sDp2 (I;f). C. elegans Animals with the Dup are Unc. Animals which have lost the Dup are DpyUncLet. Lethal early larval.
KR1537 dpy-5(e61) let-540(h884) unc-13(e450)/szT1 [lon-2(e678) unc-29(e403)] I; +/szT1 X. C. elegans Heterozygote is wild-type, segregating WT, late-larval arresting DpyUncs, szT1 homozygotes (lethal, probably embryonic), and aneuploids (dead eggs). Pick WT and check for correct segregation of progeny to maintain stock. Note that some lethals recovered by hT1 are expected to be outside the szT1 crossover suppression boundary and these strains may thus produce DpyUnc progeny. unc-29 marker may also cross away from szT1(I).
KR1577 dpy-5(e61) unc-13(e450) I; szDp1 (I;X;f). C. elegans Animals with the duplication are WT. Animals which have lost the duplication are DpyUnc. This strain was generated by the Genetic Toolkit project, which should be acknowledged in any publications resulting from its use: The Genetic Toolkit is funded by the NIH National Center for Research Resources (NCRR) (USA) to Ann M. Rose, David L. Baillie, and Donald L. Riddle. Report all experimental results to Ann Rose.
KR1588 dpy-5(e61) let-539(h938) unc-13(e450)/szT1 [lon-2(e678) unc-29(e403)] I; +/szT1 X. C. elegans Heterozygotes are WT and segregate WT, arrested DpyUncs, Lon males and large number of aneuploid progeny (arrested embyros or larvae). Note that unc-29 is outside the recombination-suppressed region of szT1 and may cross off resulting in Unc-29 progeny. Pick WT and check for correct segregation of progeny to maintain. This strain was generated by the Genetic Toolkit project, which should be acknowledged in any publications resulting from its use: The Genetic Toolkit is funded by the NIH National Center for Research Resources (NCRR) (USA) to Ann M. Rose, David L. Baillie, and Donald L. Riddle. Report all experimental results to Ann Rose.
KR1594 dpy-5(e61) let-542(h986) unc-13(e450)/szT1 [lon-2(e678) unc-29(e403)] I; +/szT1 X. C. elegans Heterozygotes are WT and segregate WT, arrested DpyUncs, Lon males and large number of aneuploid progeny (arrested embyros or larvae). Note that unc-29 is outside the recombination-suppressed region of szT1 and may cross off resulting in Unc-29 progeny. Pick WT and check for correct segregation of progeny to maintain. This strain was generated by the Genetic Toolkit project, which should be acknowledged in any publications resulting from its use: The Genetic Toolkit is funded by the NIH National Center for Research Resources (NCRR) (USA) to Ann M. Rose, David L. Baillie, and Donald L. Riddle. Report all experimental results to Ann Rose.
KR1598 dpy-5(e61) unc-13(e450) let-538(h990)/szT1 [lon-2(e678) unc-29(e403)] I; +/szT1 X. C. elegans Wild-type phenotype. Segregates WT, sterile adult DpyUncs, Lon-2 males (szT1 hemizygotes) and a large number of arrested aneuploid progeny (mostly dead eggs). Pick WT and check for correct segregation of progeny to maintain. Note that unc-29 on szT1(I) lies in the non-balanced region and may recombine onto the normal LG I.
KR1620 dpy-5(e61) unc-13(e450) I; hDp32 (I;f). C. elegans Unc-13 phenotype. Segregates Uncs and DpyUncs. The Unc-13 animals are slow growing and DpyUncs will take over; pick several Unc-13 animals to a plate to maintain. This strain was generated by the Genetic Toolkit project, which should be acknowledged in any publications resulting from its use: The Genetic Toolkit is funded by the NIH National Center for Research Resources (NCRR) (USA) to Ann M. Rose, David L. Baillie, and Donald L. Riddle. Report all experimental results to Ann Rose.
KR1621 dpy-5(e61) unc-13(e450) I; hDp33 (I;f). C. elegans Unc-13 phenotype. Segregates Uncs and DpyUncs. The Unc-13 animals are slow growing and DpyUncs will take over; pick several Unc-13 animals to a plate to maintain. This strain was generated by the Genetic Toolkit project, which should be acknowledged in any publications resulting from its use: The Genetic Toolkit is funded by the NIH National Center for Research Resources (NCRR) (USA) to Ann M. Rose, David L. Baillie, and Donald L. Riddle. Report all experimental results to Ann Rose.
KR1624 dpy-5(e61) unc-13(e450) I; hDp37 (I;f). C. elegans Unc-13 phenotype. Segregates Unc-13 and Dpy-5 Unc-13 progeny. The Unc-13 animals are slow-growing, and DpyUncs will take over population. Pick several Unc-13 animals and check for correct segregation of progeny to maintain. This strain was generated by the Genetic Toolkit project, which should be acknowledged in any publications resulting from its use: The Genetic Toolkit is funded by the NIH National Center for Research Resources (NCRR) (USA) to Ann M. Rose, David L. Baillie, and Donald L. Riddle. Report all experimental results to Ann Rose.
KR1628 dpy-5(e61) unc-13(e450) I; hDp41 (I;f). C. elegans Unc-13 phenotype. Segregates Uncs and DpyUncs. The Uncs are slow growing; the DpyUncs will take over the population. Pick several Unc-13 animals and check for correct segregation of progeny to maintain. This duplication was generated by the Genetic Toolkit project, which should be acknowledged in any publications resulting from its use: The Genetic Toolkit is funded by the NIH National Center for Research Resources (NCRR) (USA) to Ann M. Rose, David L. Baillie, and Donald L. Riddle. Report all experimental results to Ann Rose.
KR1630 dpy-5(e61) unc-13(e450) I; hDp39 (I;f). C. elegans Unc-13 phenotype. Segregates Unc-13 and Dpy-5 Unc-13 progeny. Duplication-bearing animals are slow-growing, and DpyUncs will take over population. Pick several Unc-13 animals and check for correct segregation of progeny to maintain. This strain was generated by the Genetic Toolkit project, which should be acknowledged in any publications resulting from its use: The Genetic Toolkit is funded by the NIH National Center for Research Resources (NCRR) (USA) to Ann M. Rose, David L. Baillie, and Donald L. Riddle. Report all experimental results to Ann Rose.
KR1633 dpy-5(e61) unc-13(e450) I; hDp34 (I;f). C. elegans Unc-13 phenotype. Segregates Unc-13 and Dpy-5 Unc-13. Pick Unc-13 and check for correct segregation of progeny to maintain. This strain was generated by the Genetic Toolkit project, which should be acknowledged in any publications resulting from its use: The Genetic Toolkit is funded by the NIH National Center for Research Resources (NCRR) (USA) to Ann M. Rose, David L. Baillie, and Donald L. Riddle. Report all experimental results to Ann Rose.
KR1635 dpy-5(e61) unc-13(e450) I; hDp54 (I;f). C. elegans Unc-13 phenotype. Segregates Unc-13 and Dpy-5 Unc-13. Pick Unc-13 and check for correct segregation of progeny to maintain. This strain was generated by the Genetic Toolkit project, which should be acknowledged in any publications resulting from its use: The Genetic Toolkit is funded by the NIH National Center for Research Resources (NCRR) (USA) to Ann M. Rose, David L. Baillie, and Donald L. Riddle. Report all experimental results to Ann Rose.
KR1649 dpy-5(e61) unc-13(e450) I; hDp56 (I;X;f). C. elegans hDp56-bearing animals have Unc-13 phenotype, and segregate Unc-13 and Dpy-5 Unc-13 progeny. Pick Unc-13 and check for correct segregation of progeny to maintain. This strain was generated by the Genetic Toolkit project, which should be acknowledged in any publications resulting from its use: The Genetic Toolkit is funded by the NIH National Center for Research Resources (NCRR) (USA) to Ann M. Rose, David L. Baillie, and Donald L. Riddle. Report all experimental results to Ann Rose.
KR1650 dpy-5(e61) unc-13(e450) I; hDp55 (I;f). C. elegans Unc-13 phenotype. Segregates Uncs and DpyUncs. The Uncs are slow growing; the DpyUncs will take over the population. Pick several Unc-13 animals and check for correct segregation of progeny to maintain. This duplication was generated by the Genetic Toolkit project, which should be acknowledged in any publications resulting from its use: The Genetic Toolkit is funded by the NIH National Center for Research Resources (NCRR) (USA) to Ann M. Rose, David L. Baillie, and Donald L. Riddle. Report all experimental results to Ann Rose.
KR1651 dpy-5(e61) unc-13(e450) I; hDp57 (I;f). C. elegans Unc-13 phenotype. Segregates Uncs and DpyUncs. The Unc-13 animals are slow growing and DpyUncs will take over; pick several Unc-13 animals to a plate to maintain. This strain was generated by the Genetic Toolkit project, which should be acknowledged in any publications resulting from its use: The Genetic Toolkit is funded by the NIH National Center for Research Resources (NCRR) (USA) to Ann M. Rose, David L. Baillie, and Donald L. Riddle. Report all experimental results to Ann Rose.
KR1652 dpy-5(e61) unc-13(e450) I; hDp69 (I;f). C. elegans Animals with the duplication are Dpy. Animals which have lost the duplication are DpyUnc. This strain was generated by the Genetic Toolkit project, which should be acknowledged in any publications resulting from its use: The Genetic Toolkit is funded by the NIH National Center for Research Resources (NCRR) (USA) to Ann M. Rose, David L. Baillie, and Donald L. Riddle. Report all experimental results to Ann Rose.
KR1657 dpy-5(e61) unc-13(e450) I; hDp71 (I;f). C. elegans Dpy-5 phenotype. This strain was generated by the Genetic Toolkit project, which should be acknowledged in any publications resulting from its use: The Genetic Toolkit is funded by the NIH National Center for Research Resources (NCRR) (USA) to Ann M. Rose, David L. Baillie, and Donald L. Riddle. Report all experimental results to Ann Rose.
KR1673 dpy-5(e61) unc-13(e450) I; hDp61 (I;f). C. elegans Unc-13 phenotype. Segregates Unc-13 and Dpy-5 Unc-13. Pick Unc-13 and check for correct segregation of progeny to maintain. This strain was generated by the Genetic Toolkit project, which should be acknowledged in any publications resulting from its use: The Genetic Toolkit is funded by the NIH National Center for Research Resources (NCRR) (USA) to Ann M. Rose, David L. Baillie, and Donald L. Riddle. Report all experimental results to Ann Rose.
KR1692 dpy-5(e61) unc-13(e450) let-535(h993)/szT1 [lon-2(e678) unc-29(e403)] I; +/szT1 X. C. elegans Wild-type phenotype. Segregates WT, mid-larval arrested DpyUncs, Lon-2 males (szT1 hemizygotes) and a large number of arrested aneuploid progeny (mostly dead eggs). Pick WT and check for correct segregation of progeny to maintain. Note that unc-29 on szT1(I) lies in the non-balanced region and may recombine onto the normal LG I.
KR1694 let-508(h995) dpy-5(e61) unc-13(e450)/szT1 [lon-2(e678) unc-29(e403)] I; +/szT1 X. C. elegans
KR1697 dpy-5(e61) unc-13(e450) I; hDp60 (I;f). C. elegans Unc-13 phenotype. Segregates Uncs and DpyUncs. The Unc-13 animals are slow growing and DpyUncs will take over; pick several Unc-13 animals to a plate to maintain. This strain was generated by the Genetic Toolkit project, which should be acknowledged in any publications resulting from its use: The Genetic Toolkit is funded by the NIH National Center for Research Resources (NCRR) (USA) to Ann M. Rose, David L. Baillie, and Donald L. Riddle. Report all experimental results to Ann Rose.
KR1732 dpy-14(e188) unc-13(e450) I; hDp48 (I;X;f). C. elegans WT phenotype. Segregates WT and DpyUncs. Pick WT and check for correct segregation of progeny to maintain. This strain was generated by the Genetic Toolkit project, which should be acknowledged in any publications resulting from its use: The Genetic Toolkit is funded by the NIH National Center for Research Resources (NCRR) (USA) to Ann M. Rose, David L. Baillie, and Donald L. Riddle. Report all experimental results to Ann Rose.
KR1737 hDf6 dpy-5(e61) unc-13(e450) I; hDp31 (I;f). C. elegans Unc strain that throws Uncs and dead eggs. This strain was generated by the Genetic Toolkit project, which should be acknowledged in any publications resulting from its use: The Genetic Toolkit is funded by the NIH National Center for Research Resources (NCRR) (USA) to Ann M. Rose, David L. Baillie, and Donald L. Riddle. Report all experimental results to Ann Rose.
KR278 hDf7 dpy-5(e61) unc-13(e450) I; sDp2 (I;f). C. elegans Unc-13 phenotype. Segregates Unc-13 and arrested hDf7 dpy-5 unc-13 homozygotes (probably embryos). Pick Unc-13 and check for correct segregation of progeny to maintain. This strain was generated by the Genetic Toolkit project, which should be acknowledged in any publications resulting from its use: The Genetic Toolkit is funded by the NIH National Center for Research Resources (NCRR) (USA) to Ann M. Rose, David L. Baillie, and Donald L. Riddle. Report all experimental results to Ann Rose.
KR281 dpy-5(e61) let-390(h44) unc-13(e450) I; sDp2 (I;f). C. elegans Unc-13 phenotype. Segregates Uncs and lethal DpyUncs (h44 arrests as a late larva or sterile adult). Maintain by picking Unc-13 and checking for correct segregation of progeny.
KR282 let-353(h46) dpy-5(e61) unc-13(e450) I; sDp2 (I;f). C. elegans Animals with the duplication are Unc. Animals which have lost the duplications are DpyUnc and arrest at mid-larval development. Maintain by picking Unc non-Dpy.
KR291 let-351(h43) dpy-5(e61) unc-13(e450) I; sDp2 (I;f). C. elegans Animals with the duplication are Unc. Animals which have lost the duplications are DpyUnc and arrest at mid-larval development. Maintain by picking Unc non-Dpy.
KR292 him-1(h55) dpy-5(e61) unc-13(e450) I; sDp2 (I;f). C. elegans sDp2 covers him-1 dpy-5. Pick Unc to maintain. Animals that lose the array are inviable.
KR305 let-352(h45) dpy-5(e61) unc-13(e450) I; sDp2 (I;f). C. elegans Unc-13 phenotype. Segregates Uncs and lethal DpyUncs (h45 arrests as a late larva or sterile adult). Maintain by picking Unc-13 and checking for correct segregation of progeny.
KR332 dhc-1(h79) dpy-5(e61) unc-13(e450) I; sDp2 (I;f). C. elegans Animals with the duplication are Unc. Animals which have lost the duplications are DpyUnc and arrest at mid-larval development. Maintain by picking Unc non-Dpy. Previously called let-354(h79).
KR346 let-360(h96) dpy-5(e61) unc-13(e450) I; sDp2 (I;f). C. elegans Animals with the Dup are Unc. Animals which have lost the Dup are DpyUnc and arrest in late larval development.
KR348 let-359(h94) dpy-5(e61) unc-13(e450) I; sDp2 (I;f). C. elegans Unc-13 phenotype. Segregates Uncs and lethal DpyUncs (h94 arrests as a sterile adult). Maintain by picking Unc-13 and checking for correct segregation of progeny.
KR349 mcm-4(h92) dpy-5(e61) unc-13(e450) I; sDp2 (I;f). C. elegans Animals with the duplication are Unc. Animals which have lost the duplication are DpyUnc and arrest in early larval development.
KR352 let-357(h89) dpy-5(e61) unc-13(e450) I; sDp2 (I;f). C. elegans Strain throws Unc and DpyUncLets. DpyUncLets are sterile adults. Maintain by picking Unc.
KR353 ddx-27(h86) dpy-5(e61) unc-13(e450) I; sDp2 (I;f). C. elegans Animals with the Dup are Unc. Animals which have lost the Dup are DpyUncLet (embryonic arrest).
KR354 teg-4(h85) dpy-5(e61) unc-13(e450) I; sDp2 (I;f). C. elegans Animals with the Dup are Unc. Animals which have lost the Unc are DpyUncLet. Lethal early larval. Maintain by picking Unc.
KR355 dpy-5(e61) ints-1(h84) unc-13(e450) I; sDp2 (I;f). C. elegans Unc-13 phenotype. Segregates Uncs and lethal DpyUncs (h84 arrests as a late larva or sterile adult). Maintain by picking Unc-13 and checking for correct segregation of progeny.
KR356 let-356(h83) dpy-5(e61) unc-13(e450) I; sDp2 (I;f). C. elegans Animals with the duplication are Unc. Animals which have lost the duplications are DpyUnc and arrest at mid-larval development. Maintain by picking Unc non-Dpy.
KR357 dpy-5(e61) nuo-2(h82) unc-13(e450) I; sDp2 (I;f). C. elegans Unc-13 phenotype. Segregates Uncs and lethal DpyUncs (h82 arrests as a mid-stage larva). Maintain by picking Unc-13 and checking for correct segregation of progeny.
KR359 dpy-5(e61) knl-2(h80) unc-13(e450) I; sDp2 (I;f). C. elegans Unc-13 phenotype. Segregates Uncs and lethal DpyUncs (h80 arrests as a late larva). Maintain by picking Unc-13 and checking for correct segregation of progeny.
KR387 unc-13(e450) rec-1(s180) I. C. elegans
KR423 sep-1(h108) dpy-5(e61) unc-13(e450) I; sDp2 (I;f). C. elegans Animals with the duplication are Unc. Animals which have lost the duplication are DpyUncLet.
KR424 dpy-5(e61) let-383(h115) unc-13(e450) I; sDp2 (I;f). C. elegans Animals with the Dup are Unc. Animals which have lost the Dup arrest as early-mid larvae.