Variation Information: e450

Namee450 View on WormBase
Species C. elegans
Genetic positionI:2.07 +/- 0.000 cM
Genomic positionI: 7435173..7435173
Protein change Substitution

Strains carrying this variation

Strain Genotype Species Description
AG151 cdc-25.1(nr2036)/dpy-5(e61) unc-13(e450) I. C. elegans Heterozygotes are WT and segregate WT, DpyUncs and adult steriles. Original deletion from Axys Pharmaceuticals.
AG165 san-1(av31) unc-13(e450) I. C. elegans Unc. Reduced brood size. Larval lethal, larval arrest. Steriles. Bursts at vulva. Can be maintained as a homozygote.
CB450 unc-13(e450) che-3(ky1018) I. C. elegans Paralyzed Unc. This strain carries a tightly linked mutation, che-3(ky1018), that changes Q1107 of che-3 to a stop codon. Reference: Larsch, et al. (2015) Cell Reports.
DR478 unc-13(e450) I; sup-7(st5) X. C. elegans sup-7 suppresses unc-13. Movement not WT. Fertility is low. Grows between 22.5C and 24C.
DR497 unc-13(e450) I; daf-7(m62) III; sup-7(st5) X. C. elegans Both unc-13 and daf-7 are suppressed by sup-7. sup-7 should be grown between 22.5C and 24C.
DR508 unc-13(e450) I; daf-4(m72) III; sup-7(st5) X. C. elegans sup-7 suppress dauer formation. sup-7 should be grown between 22.5C and 24C.
KR1054 dpy-5(e61) unc-13(e450)/hT1 I; +/hT1 [unc-42(e270)] V. C. elegans Pick wild-type to maintain. Segregates wild-type, Dpy Unc, arrested hT1 homozygotes, and dead eggs. Reference: McKim KS, et al. Genetics. 1988 Dec;120(4):987-1001. This strain was generated by the Genetic Toolkit project, which should be acknowledged in any publications resulting from its use: The Genetic Toolkit is funded by the NIH National Center for Research Resources (NCRR) (USA) to Ann M. Rose, David L. Baillie, and Donald L. Riddle. Report all experimental results to Ann Rose.
KR1115 dpy-5(e61) unc-13(e450) hDf9/szT1 [lon-2(e678)] I; +/szT1 X. C. elegans Wild-type phenotype, Him. Segregates wild-type, Lon-2 males and two classes of arrested embryos (dpy-5 unc-13 hDf9 homozygotes and szT1 aneuploids). Lon males are fertile, carrying hDf9 and both szT1 half translocations (arising by meiotic nondisjunction of normal X chromosome). Maintain by picking wild-type and checking for correct segregation of progeny. This strain was generated by the Genetic Toolkit project, which should be acknowledged in any publications resulting from its use: The Genetic Toolkit is funded by the NIH National Center for Research Resources (NCRR) (USA) to Ann M. Rose, David L. Baillie, and Donald L. Riddle. Report all experimental results to Ann Rose.
KR1233 hDf8/dpy-5(e61) unc-13(e450) I. C. elegans Slow-growing wild-type, Him. Segregates WT, DpyUnc, WT males and dead eggs (hDf8 homozygotes). Heterozygotes also exhibit low-penetrance vulval blips; these may be more pronounced, present at higher frequency and accompanied at times by tail blips upon recovery from starvation. hDf8 dominantly suppresses recombination from around unc-13 at least to dpy-5, and possibly to the left end of chromosome I. Maintain by picking WT and checking for correct segregation of progeny. This strain was generated by the Genetic Toolkit project, which should be acknowledged in any publications resulting from its use: The Genetic Toolkit is funded by the NIH National Center for Research Resources (NCRR) (USA) to Ann M. Rose, David L. Baillie, and Donald L. Riddle. Report all experimental results to Ann Rose.
KR1315 let-626(h676) dpy-5(e61) unc-13(e450) I; sDp2 (I;f). C. elegans Animals with the duplication are Unc. Animals which have lost the duplication are DpyUnc and arrest in late larval development.
KR1319 dpy-5(e61) nars-1(h680) unc-13(e450) I; sDp2 (I;f). C. elegans Unc-13 phenotype. Segregates Uncs and lethal DpyUncs. h680 arrests as an early larva. Maintain by picking Unc-13 and checking for correct segregation of progeny.
KR1327 let-635(h688) dpy-5(e61) unc-13(e450) I; sDp2 (I;f). C. elegans Animals with the duplication are Unc. Animals which have lost the duplication are DpyUnc and arrest in early/late larval development.
KR1328 let-636(h689) dpy-5(e61) unc-13(e450) I; sDp2 (I;f). C. elegans Animals with the duplication are Unc. Animals which have lost the duplication are DpyUnc and arrest in early larval development.
KR1329 let-520(h690) dpy-5(e61) unc-13(e450) I; sDp2 (I;f). C. elegans Unc strain which throws DpyUncLet. Late larval arrest (L4). Maintain by picking Unc non-Dpy.
KR1331 let-544(h692) dpy-5(e61) unc-13(e450) I; sDp2 (I;f). C. elegans Unc strain which throws Unc and DpyUnc (animals which have lost the Dp). DpyUncs arrest as adults. Maintain by picking Unc.
KR1334 let-610(h695) dpy-5(e61) unc-13(e450) I; sDp2 (I;f). C. elegans Unc-13 phenotype. Segregates Uncs and lethal DpyUncs (h695 arrests as a sterile adult). Pick Unc-13 animals to maintain. This strain was generated by the Genetic Toolkit project, which should be acknowledged in any publications resulting from its use: The Genetic Toolkit is funded by the NIH National Center for Research Resources (NCRR) (USA) to Ann M. Rose, David L. Baillie, and Donald L. Riddle. Report all experimental results to Ann Rose.
KR1335 let-633(h696) dpy-5(e61) unc-13(e450) I; sDp2 (I;f). C. elegans Animals with the duplication are Unc. Animals which have lost the duplication are Dpy Unc and arrest in early larval development.
KR1338 let-501(h714) dpy-5(e61) unc-13(e450) I; sDp2 (I;f). C. elegans Animals with the duplication are Unc. Animals which have lost the duplication are DpyUnc and arrest in early larval development.
KR1339 dpy-5(e61) let-532(h715) unc-13(e450) I; sDp2 (I;f). C. elegans Animals with the duplication are Unc. Animals which have lost the duplication are lethal DpyUncs.
KR1341 let-637(h700) dpy-5(e61) unc-13(e450) I; sDp2 (I;f). C. elegans Animals with the duplication are Unc. Animals which have lost the duplication are DpyUnc and arrest in mid/late larval development.
KR1345 let-521(h704) dpy-5(e61) unc-13(e450) I; sDp2 (I;f). C. elegans Unc strain which throws Unc and DpyUncs which arrest late larval (L4). Maintain by picking Unc.
KR1346 let-579(h705) dpy-5(e61) unc-13(e450) I; sDp2 (I;f). C. elegans Animals with the duplication are Unc. Animals which have lost the duplication are DpyUnc and arrest in mid larval development.
KR1347 dpy-5(e61) ncbp-1(h706) unc-13(e450) I; sDp2 (I;f). C. elegans Unc strain which throws Unc and DpyUncs which arrest as early larvae (which live 2 weeks). Maintain by picking Unc.
KR1350 let-580(h709) dpy-5(e61) unc-13(e450) I; sDp2 (I;f). C. elegans Animals with the duplication are Unc. Animals which have lost the duplication are DpyUnc and arrest in egg/early larval development.
KR1355 let-114(h716) dpy-5(e61) unc-13(e450) I; sDp2 (I;f). C. elegans Animals with the duplication are Unc. Animals which have lost the duplication are DpyUnc and arrest in early/mid larval development.
KR1366 unc-11(h725) dpy-5(e61) unc-13(e450) I; sDp2 (I;f). C. elegans Animals with the duplication are Unc. Animals which have lost the duplication are DpyUnc and arrest in mid larval development.
KR1367 let-582(h726) dpy-5(e61) unc-13(e450) I; sDp2 (I;f). C. elegans Animals with the duplication are Unc. Animals which have lost the duplication are DpyUnc and arrest in early larval development.
KR1371 let-515(h730) dpy-5(e61) unc-13(e450) I; sDp2 (I;f). C. elegans Animals with the duplication are Unc. Animals which have lost the duplication are DpyUnc and arrest in early larval development.
KR1374 dpy-5(e61) let-502(h733) unc-13(e450) I; sDp2 (I;f). C. elegans Unc-13 phenotype. Segregates Uncs and lethal DpyUncs. Pick Unc-13 animals to maintain. This strain was generated by the Genetic Toolkit project, which should be acknowledged in any publications resulting from its use: The Genetic Toolkit is funded by the NIH National Center for Research Resources (NCRR) (USA) to Ann M. Rose, David L. Baillie, and Donald L. Riddle. Report all experimental results to Ann Rose.
KR1376 dpy-5(e61) let-522(h735) unc-13(e450) I; sDp2 (I;f). C. elegans Unc-13 phenotype. Segregates Uncs and lethal DpyUncs (h735 arrests as an early larva). Pick Unc-13 animals to maintain. This strain was generated by the Genetic Toolkit project, which should be acknowledged in any publications resulting from its use: The Genetic Toolkit is funded by the NIH National Center for Research Resources (NCRR) (USA) to Ann M. Rose, David L. Baillie, and Donald L. Riddle. Report all experimental results to Ann Rose.
KR1379 let-583(h738) dpy-5(e61) unc-13(e450) I; sDp2 (I;f). C. elegans Animals with the duplication are Unc. Animals which have lost the duplication are DpyUnc and arrest in early/mid larval development.
KR1381 let-510(h740) dpy-5(e61) unc-13(e450) I; sDp2 (I;f). C. elegans Animals with the duplication are Unc. Animals which have lost the duplication are DpyUnc and arrest in early larval development.
KR1384 let-584(h743) dpy-5(e61) unc-13(e450) I; sDp2 (I;f). C. elegans Animals with the duplication are Unc. Animals which have lost the duplication are DpyUnc and arrest as Sterile adults.
KR1392 dpy-5(e61) let-523(h751) unc-13(e450) I; sDp2 (I;f). C. elegans Unc-13 phenotype. Segregates Uncs and lethal DpyUncs. h751 arrests as an early larva. Maintain by picking Unc-13 and checking for correct segregation of progeny.
KR1393 dpy-5(e61) let-513(h752) unc-13(e450) I; sDp2 (I;f). C. elegans Unc-13 phenotype. Segregates Uncs and lethal DpyUncs (h752 arrests as a sterile adult). Pick Unc-13 animals to maintain. This strain was generated by the Genetic Toolkit project, which should be acknowledged in any publications resulting from its use: The Genetic Toolkit is funded by the NIH National Center for Research Resources (NCRR) (USA) to Ann M. Rose, David L. Baillie, and Donald L. Riddle. Report all experimental results to Ann Rose.
KR1394 dpy-5(e61) let-514(h753) unc-13(e450) I; sDp2 (I;f). C. elegans Unc-13 phenotype. Segregates Uncs and lethal DpyUncs (h753 arrests as an early larva). Pick Unc-13 animals to maintain. This strain was generated by the Genetic Toolkit project, which should be acknowledged in any publications resulting from its use: The Genetic Toolkit is funded by the NIH National Center for Research Resources (NCRR) (USA) to Ann M. Rose, David L. Baillie, and Donald L. Riddle. Report all experimental results to Ann Rose.
KR1396 let-511(h755) dpy-5(e61) unc-13(e450) I; sDp2 (I;f). C. elegans Animals with the duplication are Unc. Animals which have lost the duplication are DpyUnc and arrest in early larval development.
KR1406 unc-37(h763) dpy-5(e61) unc-13(e450) I; sDp2 (I;f). C. elegans
KR1408 let-647(h765) dpy-5(e61) unc-13(e450) I; sDp2 (I;f). C. elegans Animals with the duplication are Unc. Animals which have lost the duplication are DpyUnc and arrest in early/mid larval development.
KR1411 let-627(h768) dpy-5(e61) unc-13(e450) I; sDp2 (I;f). C. elegans Animals with the duplication are Unc. Animals which have lost the duplication are Dpy Unc and arrest in early larval development.
KR1421 let-638(h778) dpy-5(e61) unc-13(e450) I; sDp2 (I;f). C. elegans Animals with the duplication are Unc. Animals which have lost the duplication are Dpy Unc and arrest in early-late larval development.
KR1422 let-639(h779) dpy-5(e61) unc-13(e450) I; sDp2 (I;f). C. elegans Animals with the duplication are Unc. Animals which have lost the duplication are DpyUnc and arrest in mid larval development.
KR1424 let-648(h781) dpy-5(e61) unc-13(e450) I; sDp2 (I;f). C. elegans Animals with the duplication are Unc. Animals which have lost the duplication are DpyUnc and arrest in early larval development.
KR1427 inx-13(h784) dpy-5(e61) unc-13(e450) I; sDp2 (I;f). C. elegans Unc-13 phenotype. Segregates Uncs and lethal DpyUncs (h784 arrests in early larval development). This strain was generated by the Genetic Toolkit project, which should be acknowledged in any publications resulting from its use: The Genetic Toolkit is funded by the NIH National Center for Research Resources (NCRR) (USA) to Ann M. Rose, David L. Baillie, and Donald L. Riddle. Report all experimental results to Ann Rose.
KR1433 let-640(h790) dpy-5(e61) unc-13(e450) I; sDp2 (I;f). C. elegans Animals with the duplication are Unc. Animals which have lost the duplication are DpyUnc and arrest in early larval development.
KR1435 let-543(h792) dpy-5(e61) unc-13(e450) I; sDp2 (I;f). C. elegans Unc strain which throws Unc and DpyUncs which arrest late larval (L4). Maintain by picking Unc.
KR1440 dpy-5(e61) vps-34(h797) unc-13(e450) I; sDp2 (I;f). C. elegans Unc-13 phenotype. Segregates Uncs and lethal DpyUncs (h797 arrests as a mid-stage larva). Pick Unc-13 animals to maintain. This strain was generated by the Genetic Toolkit project, which should be acknowledged in any publications resulting from its use: The Genetic Toolkit is funded by the NIH National Center for Research Resources (NCRR) (USA) to Ann M. Rose, David L. Baillie, and Donald L. Riddle. Report all experimental results to Ann Rose. See also WBPaper00005216. h797 pka let-512(h797).
KR1441 dpy-5(e61) let-530(h798) unc-13(e450) I; sDp2 (I;f). C. elegans Unc-13 phenotype. Segregates Uncs and lethal DpyUncs. Pick Unc-13 animals to maintain. This strain was generated by the Genetic Toolkit project, which should be acknowledged in any publications resulting from its use: The Genetic Toolkit is funded by the NIH National Center for Research Resources (NCRR) (USA) to Ann M. Rose, David L. Baillie, and Donald L. Riddle. Report all experimental results to Ann Rose.
KR1459 dpy-5(e61) unc-13(e450)/hT1 [unc-29(e403)] I; +/hT1 [unc-42(e270)] V. C. elegans Pick wild-type to maintain. Segregates wild-type, Dpy Unc, arrested hT1 homozygotes, and dead eggs. Reference: McKim KS, et al. Genetics. 1988 Dec;120(4):987-1001.
KR1478 cogc-1(h816) dpy-5(e61) unc-13(e450) I; sDp2 (I;f). C. elegans Animals with the duplication are Unc. Animals which have lost the duplication are DpyUnc and arrest in early larval development.