Variation Information: e151

Namee151 View on WormBase
Species C. elegans
Genetic positionX:21.32 +/- 0.000 cM
Genomic positionX: 14781635..14781635
Protein changeY16B4A.1 Substitution

Strains carrying this variation

Strain Genotype Species Description
AF1 +/szT1 [lon-2(e678)] I; dpy-8(e1321) unc-3(e151)/szT1 X. C. elegans Heterozygotes are WT and segregate WT, DpyUnc, dead eggs and Lon males. Maintain by picking WT.
AV311 dpy-18(e364) unc-3(e151) meT7 (III;X;IV). C. elegans Dpy. Unc. meT7 is an end-to-end-to-end fusion of chromosomes III, X, and V. The right end of III is fused to the left end of X, and the right end of X is fused to the left end of IV. Constructed by crossing eT5 and mnT12. meT7 homozygotes produce 92% viable progeny. meT7 heterozygotes are Him and produce many dead eggs.
CB151 unc-3(e151) X. C. elegans Unc.
CGC28 +/szT1 [lon-2(e678) umnIs17] I; dpy-8(e1321) unc-3(e151)/szT1 X. C. elegans umnIs17 [myo-2p::GFP + NeoR, X: 6745526 (intergenic)] I. Heterozygotes are wild-type GFP+, and segregate wild-type GFP+, DpyUnc non-GFP, dead eggs and GFP+ Lon males. Maintain by picking wild-type GFP+. Derived by insertion of myo-2p::GFP transgene into szT1 balancer in parental strain AF1 using CRISPR/Cas9.
CGC35 +/szT1 [lon-2(e678) umnIs24] I; dpy-8(e1321) unc-3(e151)/szT1 X. C. elegans umnIs24 [myo-2p::GFP + NeoR, X: 15420938 (intergenic)] I. Heterozygotes are wild-type GFP+, and segregate wild-type GFP+, DpyUnc non-GFP, dead eggs and GFP+ Lon males. Maintain by picking wild-type GFP+. Derived by insertion of myo-2p::GFP transgene into szT1 balancer in parental strain AF1 using CRISPR/Cas9.
CGC36 mnDp1 [umnIs25] (X;V)/+ V; unc-3(e151) X. C. elegans umnIs25 [myo-2p::GFP + NeoR, X: 15420938 (intergenic)]. Pick wild-type GFP+ to maintain. Segregates lethals: homozygous Dp/Dp are lethal. Derived by insertion of myo-2p::GFP transgene into mnDp1 duplication in parental strain SP219 using CRISPR/Cas9.
CGC37 unc-3(e151) X; mnDp3 [umnIs26] (X;f). C. elegans umnIs26 [myo-2p::GFP + NeoR, X: 15420938 (intergenic)]. Pick wild-type GFP+ to maintain. Segregates wild-type GFP+ and Unc GFP-. Derived by insertion of myo-2p::GFP transgene into mnDp3 duplication in parental strain SP123 using CRISPR/Cas9.
CGC40 +/szT1 [lon-2(e678) umnIs29] I; dpy-8(e1321) unc-3(e151)/szT1 X. C. elegans umnIs29 [myo-2p::mKate2 + NeoR, X: 6745526 (intergenic)] I. Heterozygotes are wild-type mKate2+, and segregate wild-type mKate2+, DpyUnc non-GFP, dead eggs and mKate2+ Lon males. Maintain by picking wild-type mKate2+. Derived by insertion of myo-2p::mKate2 transgene into szT1 balancer in parental strain AF1 using CRISPR/Cas9.
CGC41 +/szT1 [lon-2(e678) umnIs30 umnIs24] I; dpy-8(e1321) unc-3(e151)/szT1 X. C. elegans umnIs30 [myo-2p::mKate2 + NeoR, X: 6745526 (intergenic)] I. umnIs24 [myo-2p::GFP + NeoR, X: 15420938 (intergenic)] I. Carries szT1 balancer with mKate2 tag on left arm and GFP tag on right arm. Heterozygotes are wild-type GFP+ & mKate2+, and segregate wild-type GFP+ & mKate2+, DpyUnc non-GFP & non-mKate2, dead eggs and GFP+ & mKate2+ Lon males. Maintain by picking wild-type with GFP+ & mKate2+. Derived by insertion of myo-2p::mKate transgene into szT1 balancer in parental strain CGC35 using CRISPR/Cas9.
CGC42 mnDp10 [umnIs31] (X;I); unc-3(e151) X. C. elegans umnIs31 [myo-2p::GFP + NeoR, X: 15420938 (intergenic)] I. Segregates mostly wild-type GFP+ and occasional Unc GFP-. Maintain by picking WT GFP+. Derived by insertion of myo-2p::GFP transgene into mnDp10 duplication in parental strain SP117 using CRISPR/Cas9.
CGC46 +/szT1 [lon-2(e678)] I; dpy-8(e1321) unc-3(e151)/szT1 [umnIs35] X. C. elegans umnIs35 [myo-2p::GFP + NeoR, I: 6284001 (intergenic)] X. Heterozygotes are wild-type GFP+, and segregate wild-type GFP+, DpyUnc non-GFP, dead eggs and GFP+ Lon males. Maintain by picking wild-type GFP+. Derived by insertion of myo-2p::GFP transgene into szT1 balancer in parental strain AF1 using CRISPR/Cas9.
CGC50 +/szT1 [lon-2(e678) umnIs39] I; dpy-8(e1321) unc-3(e151)/szT1 [umnIs40] X. C. elegans umnIs39 [myo-2p::mKate2 + NeoR, X: 6745526 (intergenic)] I. umnIs40 [myo-2p::GFP + NeoR, I: 6284001 (intergenic)] X. Heterozygotes are wild-type GFP+ & mKate2+, and segregate wild-type GFP+ & mKate2+, DpyUnc non-GFP & non-mKate2, dead eggs, and GFP+ & mKate2+ Lon males. Maintain by picking wild-type with GFP+ & mKate2+. Derived by simultaneous insertion of independent myo-2p::mKate2 and myo-2p::GFP transgenes into each portion of the szT1 balancer in parental strain AF1 using CRISPR/Cas9.
CGC79 +/szT1 [lon-2(e678) umnIs61] I; dpy-8(e1321) unc-3(e151)/szT1 X. C. elegans umnIs61 [myo-2p::mKate2 + NeoR, X: 15420938 (intergenic)] I. Heterozygotes are wild-type mKate2+, and segregate wild-type mKate2+, DpyUnc non-mKate2, dead eggs and mKate2+ Lon males. Maintain by picking wild-type mKate2+. Derived by insertion of myo-2p::mKate2 transgene into szT1 balancer in parental strain AF1 using CRISPR/Cas9.
CGC97 +/szT1 [lon-2(e678)] I; dpy-8(e1321) unc-3(e151)/szT1 [umnIs77] X. C. elegans umnIs77 [myo-2p::mKate2 + NeoR, I: 6284001 (intergenic)] X. Heterozygotes are wild-type mKate2+, and segregate wild-type mKate2+, DpyUnc non-mKate2, dead eggs and mKate2+ Lon males. Maintain by picking wild-type mKate2+. Derived by insertion of myo-2p::mKate2 transgene into szT1 balancer in parental strain AF1 using CRISPR/Cas9.
DR111 him-4(e1266) unc-3(e151) X. C. elegans Unc. Segregates males.
DR1290 dpy-6(e14) unc-3(e151) X. C. elegans Medium sized Dpy which curls its tail.
GR1452 veIs13 V; let-7(mn112) unc-3(e151) X; mgEx725. C. elegans veIs13 [col-19::GFP + rol-6(su1006)] V. mgEx725 [lin-4::let-7 + ttx-3::RFP]. Pick RFP+ to maintain. mgEx725 rescues lethality of let-7(mn112). Precocious expression of col-19::GFP at the L4 stage. Reference: Hayes GD, Riedel CG, Ruvkun G. 2011. Genes Dev. 2011 Oct 1;25(19):2079-92.
GS3754 sel-13(ok303) III; arIs51 IV; sel-7(n1253) unc-3(e151) X. C. elegans arIs51[cdh-3::GFP]. sel-13=T04A8.10. Reported strong daf-c; raise at 15 C (personal communication to the CGC). Do not distribute this strain; other labs should request it from the CGC. This strain cannot be distributed to commercial organizations. This strain cannot be used for any commercial purpose or for work on human subjects.
KR1876 +/hT3[dpy-5(e61)] I; dpy-7(e88) unc-3(e151)/hT3 X. C. elegans Heterozygotes are WT and segregate WT, DpyUncs and Dpys. Balancer is quite unstable and prone to breaking down. Grows better at 15C.
KR926 hDf6 dpy-5(e61) unc-13(e450)/szT1 [lon-2(e678)] I; unc-3(e151)/szT1 X. C. elegans This strain was generated by the Genetic Toolkit project, which should be acknowledged in any publications resulting from its use: The Genetic Toolkit is funded by the NIH National Center for Research Resources (NCRR) (USA) to Ann M. Rose, David L. Baillie, and Donald L. Riddle. Report all experimental results to Ann Rose.
MT2490 unc-3(e151) lin-15B&lin-15A(n765) X. C. elegans Unc. Temperature sensitive Muv.
MT2718 let-2(n1279) unc-3(e151) X; mnDp26 (X;f). C. elegans n1279 is lethal. Animals which are alive contain the duplication. n1279 pka sup-20.
NOA2 lin-12(n137n460) III; him-5(e1467) V; unc-3(e151) let-7(mn112) X. C. elegans
OH10819 unc-3(e151) X; vsIs48; otEx4441. C. elegans otEx4441 [hsp-16.2p::unc-3(cDNA) + ttx-3::mCherry]. vsIs48 [unc-17::GFP]. GFP expressed in all cholinergic neurons. Maintain by picking mCherry(+) animals. Reference: Kratsios P, et al. Nat Neurosci. 2011 Nov 27. doi: 10.1038/nn.2989.
OH10850 unc-3(e151) X; otEx4432. C. elegans otEx4432 [ace-2p(SL2 fosmid)::GFP + elt-2::DsRed2]. Fosmid-based reporter. Maintain by picking DsRed2(+) animals. Reference: Kratsios P, et al. Nat Neurosci. 2011 Nov 27. doi: 10.1038/nn.2989.
OH10851 juIs14 IV; unc-3(e151) X; otEx4812. C. elegans otEx4812 [unc-30p(2.6kb promoter)::unc-3(cDNA)::unc-54 3'UTR + myo-2::GFP]. juIs14 [acr-2p::GFP + lin-15(+)]. Maintain by picking myo-2::GFP(+) animals. Reference: Kratsios P, et al. Nat Neurosci. 2011 Nov 27. doi: 10.1038/nn.2989.
PQ425 apIs320 II; unc-119(ed3) III; unc-3(e151) let-7(mn112) X. C. elegans apIs320 [let-7::unc-119(+)] II. PQ425 was created by crossing PQ320 into unc-3(e151) let-7(mn112) animals, which do not express precursor or mature let-7. unc-119(ed3) might not be homozygous in this strain. Reference: Zisoulis DG, et al. Nature. 2012;486(7404):541-544.
PQ426 apIs404 II; unc-119(ed3) III; unc-3(e151) let-7(mn112) X. C. elegans apIs404 [let-7(delta alg-1-binding site)::unc-119(+)] II. PQ426 was created by crossing PQ404 into unc-3(e151) let-7(mn112) animals, which do not express precursor or mature let-7. unc-119(ed3) might not be homozygous in this strain. Reference: Zisoulis DG, et al. Nature. 2012;486(7404):541-544.
PS1478 unc-3(e151) lin-15B&lin-15A(e1763) X. C. elegans Unc. Muv. Do not distribute this strain; other labs should request it from the CGC. This strain cannot be distributed to commercial organizations. This strain cannot be used for any commercial purpose or for work on human subjects.
QP122 dpy-3(e27) lon-2(e678) unc-3(e151) X. C. elegans Dpy. Unc. dpy-3 is epistatic to lon-2.
RW1385 mnDp1 (X;V)/+ V; unc-3(e151) pat-9(st558) X. C. elegans Animals with the duplication are WT and segregate WT, sterile and Pats. Strain can be propagated by chunking.
SP115 mnDp8 (X;I); unc-3(e151) X. C. elegans WT strain.
SP116 mnDp9 (X;I); unc-3(e151) X. C. elegans WT strain.
SP117 mnDp10 (X;I); unc-3(e151) X. C. elegans WT strain. Occassionally Uncs appear.
SP122 unc-3(e151) X; mnDp2 (X;f). C. elegans Strain throws WT and Uncs. Maintain by picking WT.
SP123 unc-3(e151) X; mnDp3 (X;f). C. elegans Strain throws WT and Uncs. Maintain by picking WT.
SP124 unc-3(e151) X; mnDp4 (X;f). C. elegans Strain throws WT and Uncs. Maintain by picking WT.
SP125 unc-3(e151) X; mnDp5 (X;f). C. elegans FREE DUPLICATION. Strain throws WT and Uncs. Maintain by picking WT.
SP14 unc-3(e151) unc-7(e139) X. C. elegans
SP15 unc-9(e101) unc-3(e151) X. C. elegans
SP1882 dpy-1(e1) ncl-1(e1865) III; unc-3(e151) osm-1(p808) X; mnDp92 [dpy-1(+) ncl-1(+) unc-3(+) osm-1(+)] (III;X;f). C. elegans Animals with mnDp92 are WT. Animals which have lost mnDp92 are DpyUncOsm and Ncl. Males containing mnDp92 are fertile. mnDp92 was derived by fusing mnDp14 and mnDp90.
SP1911 dpy-1(e1) ncl-1(e1865) III; unc-3(e151) osm-1(p808) X; mnDp91 (III;X;f). C. elegans Animals with mnDp91 are WT. Animals which have lost mnDp91 are DpyUncOsm and Ncl. mnDp91 derived by fusing mnDp14 and mnDp90.
SP219 mnDp1 (X;V)/+ V; unc-3(e151) X. C. elegans Pick WT to maintain. Segregates lethals. Dp/Dp are homozygous lethal.
SP223 mnDp1 (X;V)/+ V; unc-3(e151) let-3(mn104) X. C. elegans LETHAL EARLY LARVAL Pick WT to maintain.
SP224 mnDp1 (X;V)/+ V; let-4(mn105) unc-3(e151) X. C. elegans Lethal early larval. Maintain by picking WT.
SP225 mnDp1 (X;V)/+ V; let-5(mn106) unc-3(e151) X. C. elegans LETHAL LATE LARVAL MATERNAL EFFECT Pick WT to maintain.
SP226 mnDp1 (X;V)/+ V; let-9(mn107) unc-3(e151) X. C. elegans Pick WT to maintain. Throws WT, Sterile Uncs, and dead eggs(homozygous Dp).
SP231 mnDp1(X;V)/+ V; unc-3(e151) let-7(mn112) X. C. elegans LETHAL LATE LARVAL SEX-INFLUENCED Maintain by picking WT.
SP232 mnDp1 (X;V)/+ V; unc-3(e151) let-10(mn113) X. C. elegans LETHAL EARLY LARVAL. Maintain by picking WT.
SP233 mnDp1(X;V)/+ V; unc-3(e151) let-2(mn114) X. C. elegans