Variation Information: e1091

Namee1091 View on WormBase
Species C. elegans
Genetic positionI:2.07 +/- 0.004 cM
Genomic positiongenomic coordinates unknown or not listed
Protein changeprotein change unknown or not listed

Strains carrying this variation

Strain Genotype Species Description
AC68 unc-29(e1072) aph-2(zu181)/unc-13(e1091) lin-11(n566) I. C. elegans Heterozygotes are WT and segregate WT, Unc Egls, and dead eggs.
BW1053 dpy-14(e188) unc-13(e1091) I. C. elegans Unc. Temperature-sensitive Dpy. Grows best at 15C.
BW538 unc-13(e1091) lin-10(e1438) I. C. elegans Unc and Vul.
CB1091 unc-13(e1091) I. C. elegans Unc-paralysed, kinky, small, irregular pharyngeal pumping. Suppressed by sup-5 and sup-7.
CB2167 dpy-5(e61) unc-13(e1091) I. C. elegans Dpy. Unc.
EU414 unc-13(e1091) mom-4(or39)/hT2 I; +/hT2 [bli-4(e937) let-?(h661)] III. C. elegans Heterozygotes are WT. Segregates Uncs which give only embryonic lethals which lack gut and make excess mesoderm (E adopts an MS-like fate). or39 is a recessive maternal-effect embryonic lethal.
EU443 unc-13(e1091) mom-4(or11)/hT2 I; +/hT2 [bli-4(e937) let-?(h661)] III. C. elegans Heterozygotes are WT. Segregates Uncs which give only embryonic lethals which lack gut and make excess mesoderm (E adopts an MS-like fate). or11 is a recessive maternal-effect embryonic lethal.
EU446 unc-13(e1091) mom-4(or39)/hT2 I; +/hT2 [bli-4(e937) let-?(h661)] III. C. elegans Heterozygotes are WT. Segregates Uncs which give only embryonic lethals which lack gut and make excess mesoderm (E adopts an MS-like fate). or39 is a recessive maternal-effect embryonic lethal.
EU447 unc-13(e1091) mom-4(or39)/hT2 I; +/hT2 [bli-4(e937) let-?(h661)] III; him-8(e1489) IV. C. elegans Heterozygotes are WT. Segregates Uncs which give only embryonic lethals which lack gut and make excess mesoderm (E adopts an MS-like fate). or39 is a recessive maternal-effect embryonic lethal. Throws males.
EU452 mom-5(zu193) unc-13(e1091)/hT2 I; +/hT2 [bli-4(e937) let-?(h661)] III. C. elegans Heterozgyotes are WT and segregate WT, Uncs which give only dead eggs, and dead eggs.
EU459 unc-13(e1091) mom-5(zu193)/hT2 I; +/hT2 [bli-4(e937) let-?(h661)] III; him-8(ec56) IV. C. elegans Heterozygotes are WT and segregate WT and Uncs. The Uncs have a non-conditional maternal-effect embryonic lethal phenotype: the E blastomere adopts MS fate in about 5% of mutant embryos. The Uncs are 100% penetrant for embyronic lethality and morphogenesis defects.
HR75 mei-1(b284) unc-29(e1072)/mei-1(ct46) unc-13(e1091) I. C. elegans Heterozygotes are WT. ct46 is a dominant, temperature sensitive maternal effect lethal. ct46 homozygotes are viable and fertile at 15C. b284 is a non-conditional, recessive maternal effect lethal. Heterozygotes give more viable progeny at 15C than 25C.
JK1403 fog-3(q470)/unc-13(e1091) lin-11(n566) I. C. elegans Heterozygotes are WT and segregate WT, Unc Egls and females. Do not distribute this strain; other labs should request it from the CGC. This strain cannot be distributed to commercial organizations. This strain cannot be used for any commercial purpose or for work on human subjects.
JK1545 ces-1(n703) qDf8/unc-13(e1091) lin-11(n566) I. C. elegans Heterozygotes are Ces and segregate VulUncs and dead eggs. ces-1(n703) is dominant. Do not distribute this strain; other labs should request it from the CGC. This strain cannot be distributed to commercial organizations. This strain cannot be used for any commercial purpose or for work on human subjects.
JK1547 ces-1(n703) qDf10/unc-13(e1091) lin-11(n566) I. C. elegans Heterozgotes are Ces and segregate VulUncs and dead eggs. ces-1(n703) is dominant. Do not distribute this strain; other labs should request it from the CGC. This strain cannot be distributed to commercial organizations. This strain cannot be used for any commercial purpose or for work on human subjects.
JK1548 ces-1(n703) qDf11/unc-13(e1091) lin-11(n566) I. C. elegans Heterozygotes are Ces and segregate Ces, UncVul and dead eggs. ces-1(n703) is dominant. Do not distribute this strain; other labs should request it from the CGC. This strain cannot be distributed to commercial organizations. This strain cannot be used for any commercial purpose or for work on human subjects.
JK1550 ces-1(n703) qDf12/unc-13(e1091) lin-11(n566) I. C. elegans Heterozygotes are Ces and segregate VulUnc and dead eggs. ces-1(n703) is dominant. Do not distribute this strain; other labs should request it from the CGC. This strain cannot be distributed to commercial organizations. This strain cannot be used for any commercial purpose or for work on human subjects.
JK1556 ces-1(n703) qDf14/unc-13(e1091) lin-11(n566) I. C. elegans Heterozygotes are Ces and segregate Ces, UncVul and dead eggs. ces-1(n703) is dominant. Do not distribute this strain; other labs should request it from the CGC. This strain cannot be distributed to commercial organizations. This strain cannot be used for any commercial purpose or for work on human subjects.
JK1557 ces-1(n703) qDf13/unc-13(e1091) lin-11(n566) I. C. elegans Heterozygotes are Ces and segregate VulUncs and dead eggs. ces-1(n703) is dominant. Do not distribute this strain; other labs should request it from the CGC. This strain cannot be distributed to commercial organizations. This strain cannot be used for any commercial purpose or for work on human subjects.
JM69 dpy-5(e61) unc-13(e1091)/szT1 [lon-2(e678)] I; elt-2(ca15)/szT1 X. C. elegans Heterozygotes are WT and segregate WT, Lon males and dead eggs.
MAS94 mei-1(ct46) unc-13(e1091) I; unc-119(ed3) III; abcIs3. C. elegans abcIs3 [pie-1p::ebp-2::GFP + unc-119(+)]. Embryonic-lethal at 25ÂșC due to dominant gain-of-function mutation mei-1(ct46), and Uncoordinated due to unc-13 mutation. Maternal expression of EBP-2::GFP microtubule end-binding protein. EBP-2 encodes an EB1-like protein (end-binding) that, in early embryos, locates to the growing tips of microtubules. A strong fluorescent signal localizes to the centrosomes of early embryos due to a high concentration of polymerizing microtubules. mei-1(ct46)-based ectopic microtubule severing causes mitotic spindle defects in the early embryo. References: Gusnowski EM, Srayko M. J Cell Biol. 2011 Aug 8;194(3):377-86. Tegha-Dunghu J, et al. Methods Mol Biol. 2014;1136:103-16.
MT1488 lin-17(n677) unc-13(e1091) I. C. elegans
MT2138 nDf29/unc-13(e1091) lin-11(n566) I. C. elegans
MT2139 nDf30/unc-13(e1091) lin-11(n566) I. C. elegans Heterozygotes are Vul and segregate Vul, UncVul and dead eggs. Maintain by picking Vul non-Unc.
MT2179 nDf25/unc-13(e1091) lin-11(n566) I. C. elegans Heterozygotes are WT and segregate WT, UncVul and dead eggs. The UncVuls are small, kinky, paralyzed and vulvaless. Maintain by picking WT.
MT2180 nDf23/unc-13(e1091) lin-11(n566) I. C. elegans Heterozygotes are WT and segregate WT, UncVul and dead eggs. UncVuls are small, kinky, paralyzed and vulvaless. Maintain by picking WT.
MT2181 nDf24/unc-13(e1091) lin-11(n566) I. C. elegans Hets are WT and segregate WT, dead eggs, and VulUnc. VulUncs are small, kinky, paralyzed and vulvaless. Maintain by picking WT.
MT3033 unc-13(e1091) lin-35(n745) I. C. elegans Unc.
MT3198 unc-13(e1091) unc-29(e1072) I. C. elegans
SP1540 mnDf111/unc-13(e1091) lin-11(n566) I. C. elegans Heterozygotes are WT and segregate WT, dead eggs and UncVul.
WH163 nDf29/unc-13(e1091) spd-2(oj29) I. C. elegans Heterozygotes are WT and segregate WT, dead eggs and Uncs. At 25C the Unc Spds are Sterile; at 16C the Unc Spds are fertile but produce mostly dead eggs. Unc Spd animals will exhibit a fully penetrant maternal-effect embryonic lethal phenotype if shifted to 25C at the L4 stage. unc-13 spd-2 homozygotes may be propagated at 16C but may become sick causing immense frustration! See also WBPaper00004200.
XA4804 ace-2(g72) unc-13(e1091) I; ace-1(p1000) X. C. elegans Previously called MA1104.
XA4828 unc-13(e1091) I; unc-17(e327) IV. C. elegans Previously called MA1128.
XA4832 unc-13(e1091) I; rab-3(y251) II. C. elegans Previously called MA1132.