Transgene Information
| Name | xnEx385 View on WormBase |
|---|---|
| Description | [hsp16p::HA::phplc1(delta)1::hmr-1(ICD-M) + rol-6(su1006)] |
Strains carrying this transgene
| Strain | Genotype | Species | Description |
|---|---|---|---|
| FT1569 | unc-119(ed3) III; xnIs371; xnEx385. | C. elegans | xnIs371 [pie-1p::GFP::pac-1(1-574) + unc-119(+)]. xnEx385 [hsp16p::HA::phplc1(delta)1::hmr-1(ICD-M) + rol-6(su1006)]. Rollers. Rollers express mutated HMR-1 intracellular domain (unable to bind catenins) pan-cortically in cells upon heat shock. Maintain at 15C or 20C to prevent leaky expression of heat shock transgene. Reference: Klompstra D, et al. Nat Cell Biol. 2015 Jun;17(6):726-35. |